Freely sharing resources to advance science and cures
The Childhood Solid Tumor Network (CSTN) offers the world's largest and most comprehensive collection of scientific resources for researchers studying pediatric solid tumors and related biology.
By freely sharing unique tools with no obligation to collaborate, we aim to promote global discovery and new treatments for pediatric patients with poorly understood and difficult-to-treat solid tumors.
Resources are available for a wide variety of tumor types, and include:
View lists of our orthopedic patient-derived xenografts, as well as information about data, GEMMs and other available resources.
FAQs about the process for requesting and receiving solid tumor research resources from the Childhood Solid Tumor Network.
Childhood solid tumors are often difficult to study and treat because they are rare and originate in the complex biological context of developing organs. CSTN was established to disseminate resources and data that have been developed at St. Jude Children’s Research Hospital, with the aim of stimulating basic research and speeding translation to the clinic.
The effort was launched in 2013 by Howard Hughes Medical Institute investigator Michael Dyer, PhD, of St. Jude Developmental Neurobiology, and Alberto Pappo, MD, of St. Jude Oncology.
For more information, contact us: CSTN@stjude.org
Last updated April 2022
Total Requests
644
Total Vials Sent Out
>1,800
Principal Investigators
261
Institutions
123
Countries
17
Read about our new method to produce orthotopic patient-derived xenografts. All O-PDX models and associated data are available. Please cite this reference in publications resulting from use of CSTN resources:
Stewart E, Federico S, Chen X, et al. Orthotopic patient-derived xenografts of paediatric solid tumours. Nature 549(7670):96-100, 2017.
Other research articles
David M. Langenau, Ph.D.
Associate Professor, Pathology, Harvard Medical School
Assistant Molecular Pathologist, Molecular Pathology, Massachusetts General Hospital