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Cell and Tissue Imaging Center: Light Microscopy

Accelerating the use of advanced optical imaging technologies across St Jude

OVERVIEW

Cell and Tissue Imaging Center Light Microscopy (CTIC-LM) is open to all St. Jude researchers and offers a wide range of cutting-edge imaging technologies. A team of PhD-level imaging scientists provides expert-level support on sample preparation, imaging, and image data processing techniques.

Two people looking at an image on a computer screen

IMPACT

Minimal recharge requirements allow core staff to perform extensive methods validation and make an intellectual contribution to many projects. The core also presents technology lectures throughout the year and provides educational resources. During 2024 alone, CTIC-LM engaged over 150 users from more than 60 labs in 10+ departments. CTIC-LM staff were also co-authors on several St. Jude publications.

In the news

Research

Shared Resource Spotlight: Cell and Tissue Imaging Center

Akshita Bhatt, PhD

The Cell and Tissue Imaging Center helps fuel breakthroughs using light and electron microscopy.

EQUIPMENT / SERVICES

Instruments:

Scanning and spinning disk confocals
Gaussian and Lattice light sheet
Large field-of-view TIRF
Epifluorescence and brightfield

Supported Methods:

Expansion microscopy with deconvolution
Tissue clearing and large volume rendering
SMLM sample prep and analysis
CLEM workflows in partnership with CTIC-EM
Image data analysis

View Details

Aaron Taylor, PhD

Director, Light Microscopy, Cell and Tissue Imaging Center

Email
aaron.taylor@stjude.org

Dr. Aaron Taylor received a PhD in Neuroscience from Brown University and did post-doctoral research in Developmental Neurobiology at the University of Wisconsin, Madison. Since 2010, he has managed imaging cores at Purdue University, the Janelia Research Campus, and Michigan Medicine, before joining St. Jude in 2021. Aaron was selected as a CZI Imaging Scientist in 2019.