St. Jude Reference #SJ-21-0045
Researchers at St. Jude created small molecules that target protein degradation of GSPT1/IKZF1 for the treatment of cancer (hematological malignancies, solid tumors). These compounds indicate greater potency for degradation over existing small molecules.
small molecule, drug, PROTAC. targeted protein degradation, CK1alpha, hematological cancer, solid tumor.
Granted Patents or Published Applications
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