St. Jude Family of Websites
Explore our cutting edge research, world-class patient care, career opportunities and more.
St. Jude Children's Research Hospital Home
- Fundraising
St. Jude Family of Websites
Explore our cutting edge research, world-class patient care, career opportunities and more.
St. Jude Children's Research Hospital Home
- Fundraising
-
Learn about the PG4KDs Clinical Trial
View treatment information for PG4KDS, a nontherapeutic pediatric pharmacogenetics clinical trial at St. Jude Children’s Research Hospital.
-
Implementation Resources for Professionals
Healthcare Professional Resources for the Implementation of Pharmacogenetics
-
Pharmacogenomics (Pharmacogenetics)
Pharmacogenomics, also called pharmacogenetics, is the study of how genes affect the medicines you take. Learn how pharmacogenetic testing can help doctors choose the best medicine and dose.
-
PG4KDS Patient Education Materials
Find links to material explaining pharmacogenics.
Implemented Genes
The list below includes genes that are currently being used to make drug therapy decisions for patients on the St. Jude PG4KDS study.
- Calcium Voltage-Gated Channel subunit alpha 1S (CACNA1S)
- Cytochrome P450 2B6 (CYP2B6)
- Cytochrome P450 2C19 (CYP2C19)
- Cytochrome P450 2C9 (CYP2C9)
- Cytochrome P450 2D6 (CYP2D6)
- Cytochrome P450 3A5 (CYP3A5)
- Dihydropyrimidine Dehydrogenase (DPYD)
- Glucose-6-Phosphate Dehydrogenase (G6PD)
- Mitochondrially Encoded 12S RNA (mt-RNR1)
- Ryanodine Receptor Isoform 1 (RYR1)
- SLCO1B1
- Thiopurine Methyltransferase (TPMT)
- Uridine Diphosphate Glucuronosyltransferase 1A1 (UGT1A1)
Other Important Pharmacogenes
The list below includes genes that are currently implemented at St. Jude outside of the context of the PG4KDS study.