Xiang Chen, PhD, of Computational Biology, helped develop a machine learning approach to improve epigenetic research.
St. Jude scientists have added deep learning to their cancer research toolkit. Deep learning is part of a family of machine learning methods that use artificial neural networks. It boosts the computational side of science.
MethylationToActivity (M2A) is a machine learning approach for epigenetic research. Created at St. Jude, M2A allows researchers to infer more from a single type of test.
“M2A is a method for integrating DNA methylation information to make it easier to interpret,” said Xiang Chen, PhD, of Computational Biology. “Using M2A, we can learn about promoter activity changes and gene expression changes by DNA methylation in different types of tumors.”
Scientists around the world can use M2A through St. Jude Cloud. The analysis is fast, cheap and reliable.
Genome Biology published this work.
More Information
-
St. Jude Newsroom
Visit the St. Jude newsroom to read our latest news, find media relations contacts and explore resources for journalists and bloggers.
-
Research at St. Jude
At St. Jude, science matters. From molecular breakthroughs to innovative therapies, our research discovers the cures of tomorrow, and saves children's lives today.
-
Research News & Publications
Browse the latest peer-reviewed articles from St. Jude investigators and clinicians, as well as breaking news, in-depth features and our Scientific Report.
-
About St. Jude
St. Jude Children’s Research Hospital is leading the way the world understands, treats and defeats childhood cancer and other life-threatening diseases.
-
Clinical & Research Innovation
At St. Jude, we dream big, and build our research programs to match. Explore just a few of the pioneering initiatives that make St. Jude different.
-
Careers
St. Jude is a world-class research hospital seeking a diverse staff of faculty, researchers, clinicians, fundraisers and more. Find a job and help save lives.
-
Education and Training
St. Jude offers world-class scientific and clinical training experiences for fellows, students and other trainees. We also share knowledge through international outreach.