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Why are some people better at processing sounds?
09/23/2022
St. Jude scientists identified the mechanism that gives Williams-Beuren Syndrome patients enhanced ability to discriminate between sounds as interneuron hyperexcitability in the auditory cortex.
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Where does medulloblastoma come from?
09/21/2022
St. Jude scientists found that group 3 and 4 medulloblastoma arise from the rhombic lip, which may help improve research models and therapeutic development.
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What doesn’t kill cancer can make it stronger
09/01/2022
St. Jude researchers discovered how some cancer cells survive treatment and cause cancer to recur, along with a way to stop the process.
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An ounce of DNA is worth pounds of prevention in cancer survivors
07/25/2022
St. Jude scientists found that childhood cancer survivors are at risk of obesity. They wanted a tool to identify survivors likely to become severely or “morbidly” obese as adults.
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Improving memory problems in CAR T cells
06/22/2022
St. Jude scientists identified proteins that help decide T cell fate and used the finding to improve CAR-T cell therapy in a solid tumor model.
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Heterochromatin silencing is like a piano that doesn’t make a sound
05/31/2022
St. Jude scientists have a new understanding of the pathways that contribute to this gene silencing.
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What causes inactivation of an ion channel?
05/20/2022
This the first time researchers have identified the mechanism for closed-state inactivation, and the approaches used here could be applied to other ion channels.
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Understanding EZH2 inhibitor resistance
05/09/2022
St. Jude scientists looked for resistance mechanisms in rhabdoid tumor cells and found the cells require the protein NSD1.
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Scientists reveal new cause of cancer
05/05/2022
The team looked at a poorly understood form of chronic leukemia, CLPD-NK. The results led the researchers to create a new model of cancer development.
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Study shows how a potential new class of antibiotics works
05/02/2022
Scientists at St. Jude are studying antimicrobial compounds called argyrins. Argyrins have shown some success against a bacterium called Pseudomonas aeruginosa.
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EGFR inhibitors show promise against rhabdomyosarcoma in the lab
04/27/2022
Rhabdomyosarcoma is the most common soft tissue tumor in children. When it recurs after therapy, the survival rate is only 30%.
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A tale of two tails
04/27/2022
St. Jude scientists reveal how GPCR signaling is regulated, with implications for drug development.
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“Junk” DNA can cause cancer
04/22/2022
Scientists from St. Jude found a novel cause of high-grade glioma, an aggressive pediatric brain cancer.
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Vaccination vs. infection: understanding SARS-CoV-2
04/05/2022
St. Jude scientists have studied how vaccination before and after COVID-19 infections affect the immune response.
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Study has implications for developing universal flu vaccine
03/16/2022
St. Jude scientists have found a clue as to why our immune systems do not target virus components that all flu strains share.
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Removing barriers to pediatric early warning systems
03/09/2022
PEWS are not widely used in hospitals with limited resources. To understand why, scientists at St. Jude conducted a study.
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Unique CAR T cell shows promise against AML in the lab
01/31/2022
St. Jude scientists have created a targeted strategy for destroying a type of pediatric leukemia using CAR T cells.
