Cancer is uncontrolled cell growth that arises from DNA changes, or mutations. St. Jude Cloud is the world’s largest repository of pediatric genomics data and is available to researchers worldwide.
Learn more about the Pediatric Cancer Genome Project and cancer predisposition in children at St. Jude.
The following genetics experts are available to speak to journalists on a range of topics, offer credible information, hands-on expertise and clinical insight on genetic origins of cancers, genetic risk for cancers and genetically tailored treatments in pediatric cancer.
To schedule interviews or speak with one of our experts, email email@example.com or contact one of our media relations staff.
Genetics and Genomics of Childhood Cancer Experts
James Downing, MD, is president and chief executive officer at St. Jude Children's Research Hospital, as well as the hospital’s chair of Childhood Cancer Treatment. He also directs the molecular pathology laboratory, where his research focuses on human leukemia. This laboratory investigates the role of chromosomal translocations in the development of pediatric cancers and determines how the identification of these genetic errors can be used to aid in the diagnosis and management of pediatric patients. Downing was instrumental in launching the Pediatric Cancer Genome Project, and was a finalist of TIME magazine's 100 most influential people in the world.
Gerard Grosveld, PhD, chairs the Genetics department at St. Jude Children's Research Hospital. The Grosveld laboratory studies the role of chromosomal translocations, or gene errors, in two types of childhood cancer. These chromosomal mutations create fusion genes that can transform normal cells into tumor cells. Grosveld’s research into the molecular pathways these chemical errors take will aid the development of new targeted therapies.
Jinghui Zhang, PhD, is chair of the Computational Biology department and the endowed chair of Bioinformatics at St. Jude Children's Research Hospital. As group lead for the analysis of the next-generation sequencing data provided by the Pediatric Cancer Genome Project, Zhang can be contacted about the use of big data to probe the genetic origins and fundamental driving mechanisms of pediatric cancers, including St. Jude Cloud.