The Division of Molecular Oncology is a laboratory-based research group within the Department of Oncology. Our scientists lead dynamic, high impact research labs that are highly interactive with numerous collaborations among other St. Jude laboratories and shared resources.
Basic science investigations focus on the molecular and genetic determinants of pediatric cancers and the mechanisms that drive cancer development. Current areas of interest include investigations of oncogenes and tumor suppressor genes in tumor development, such as the SWI/SNF family of chromatin remodeling proteins, origins and pathology of pediatric solid tumors and leukemias, and the role of RNA splicing factor mutations in myeloid malignancies and bone marrow failure syndromes. By identifying the mechanisms underlying these diseases, Division laboratories have been able to translate novel targeted therapies to the clinic.
Division of Molecular Oncology
MS 354, Room D5048
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
Phone: (901) 595-0248
Fax: (901) 595-0817
Preferred contact method: email
Cellular and genetic origins of childhood cancers
Molecular pathology of infantile leukemia and megakaryoblastic leukemia
Cellular and molecular origins of rhabdomyosarcoma
Myeloid malignancies and bone marrow failure syndromes
SWI/SNF (BAF) chromatin remodeling/tumor suppressor