Research

Learn about published research as well as leading-edge basic and translational research initiatives from St. Jude laboratories.

Importance of citations in scientific research: More than just bragging rights

Rebecca Tweedell, PhD

Being highly cited means your research gets published in high-impact journals and reaches more people.

Smithsonian honors St. Jude visionaries for ‘bubble boy’ cure

Mary Powers

Read how St. Jude researchers and clinicians used gene therapy to cure the diabolical bubble boy disease.

Proteins: Playing with molecular rubber duckies

Marcus Fischer, PhD

Are you a match? Read how this molecule’s affinity to proteins can change according to water.

New analytical technique reveals the subtle genetic differences among cancer cells

Xiang Chen, PhD

Sequencing data gives insights into what’s going on in a cell. It’s a lot of information. Read how scientists are finding ways to cut through the information and find causes for disease.

Genetic sequencing: How do we put out the fires of genetically driven cancers?

Jill Bouchard, PhD

Too much of a good thing? Read how genetic sequencing offers insights into the causes of some cancers, but the avalance of data creates a new set of issues.

Survivorship studies dig in on data

Kirsten Ness, PT, PhD, FAPTA

Read how cancer survivorship research reveals more about the late effects of treatment on children – and how the data can paint a more complete picture.

Research homes in on drug to dampen inflammation fueling life-threatening immune disorder

Mary Powers

Researchers have promising information that ruxolitinib may help treat a devastating auto-immune disorder.

Separating fact from fiction using pharmacogenetics

Mary Relling, PharmD

Improving understanding of drugs and how the body reacts to them - - Read how science is improving understanding of genes and medication.

Chaperones: probing the structural secrets of the cell’s front-line protein protectors

Charalampos Kalodimos, PhD

Read how this protein, called a chaperone, does more than simply monitor the intracellular dance of protein folding – it protects them from going awry.

Rare childhood disorders widen window on diseases of aging

Mary Powers

Read how extremely rare genetic childhood diseases offer clues about understanding neurodegenerative disorders common with aging.