Progress Pulse

Short summaries of scientific findings from across the St. Jude research enterprise.

Analysis provides a deep dive into PAX5 leukemia

Learn how combining techniques gave a much better look into a complex cancer.

Immune history shapes protection against bird flu

Learn how immune history influences the body’s defense against bird flu.

Global gaps in access to pediatric cancer clinical trials

Learn how researchers uncovered global gaps in access to pediatric cancer clinical trials.

Strategies for communicating with honesty and hope in uncertain prognostic situations

Discover how patient- and caregiver-derived insights from the RIGHTime study are being used to characterize best practices in patient-centered prognostic conversations.

Study links changes in the SMARCAL1 gene to increased risk for bone cancer

Researchers at St. Jude studying DNA damage repair genes have discovered a predisposition gene for osteosarcoma

Machine learning reveals sources of accelerated brain aging in childhood cancer survivors

Learn how identifying correlates of accelerated aging may help prevent neurocognitive decline.

Accelerating molecular glue discovery with a direct-to-biology approach

See how mass spectrometry can reduce lead discovery from months to hours.

Norepinephrine ‘reset switch’ affects decision-making

See how norepinephrine aids with brain remapping

Understanding adaptation and implementation challenges in pediatric ALL

Learn about the challenges of adapting and implementing pediatric acute lymphoblastic leukemia treatments in low- and middle-income countries.

Sequencing large-scale changes in DNA to detect cancer earlier

Discover how St. Jude scientists improved detection of large structural changes in DNA to identify cancer cells.