Zhaoming Wang, Ph.D., associate member of the St. Jude Departments of Epidemiology and Cancer Control and Computational Biology, talks with Leslie Robison, Ph.D., chair of the St. Jude Department of Epidemiology and Cancer Control and Kim Nichols, M.D., director of the St. Jude Cancer Predisposition Division.
A St. Jude study linked inherited mutations in the BRCA2 gene with a higher risk of non-Hodgkin lymphoma.
The work focused on childhood cancer survivors. The team looked at 1,380 survivors of pediatric lymphoma.
“BRCA genes have been linked to adult cancer for many years,” said Zhaoming Wang, PhD, of Epidemiology and Cancer Control and Computational Biology. “Our study shows a relationship between BRCA2 and non-Hodgkin lymphoma in childhood cancer survivors.”
Genetic counseling and BRCA2 testing could be useful for survivors of childhood non-Hodgkin lymphoma. Survivors with a family history of BRCA2-associated cancers may also be tested.
A report on this work was published in JAMA Oncology.
More Information
-
St. Jude Newsroom
Visit the St. Jude newsroom to read our latest news, find media relations contacts and explore resources for journalists and bloggers.
-
Research at St. Jude
At St. Jude, science matters. From molecular breakthroughs to innovative therapies, our research discovers the cures of tomorrow, and saves children's lives today.
-
Research News & Publications
Browse the latest peer-reviewed articles from St. Jude investigators and clinicians, as well as breaking news, in-depth features and our Scientific Report.
-
About St. Jude
St. Jude Children’s Research Hospital is leading the way the world understands, treats and defeats childhood cancer and other life-threatening diseases.
-
Clinical & Research Innovation
At St. Jude, we dream big, and build our research programs to match. Explore just a few of the pioneering initiatives that make St. Jude different.
-
Careers
St. Jude is a world-class research hospital seeking a diverse staff of faculty, researchers, clinicians, fundraisers and more. Find a job and help save lives.
-
Education and Training
St. Jude offers world-class scientific and clinical training experiences for fellows, students and other trainees. We also share knowledge through international outreach.