About the Department

The Department of Pharmacy and Pharmaceutical Sciences is equally committed to understanding inter-individual differences in response to medications, translating research findings to improve treatment outcomes, and providing the best and most comprehensive clinical care for our patients. The translational space created by the combination of fundamental research efforts and clinical application is transformative for patients and families. The Department comprises The Division of Pharmaceutical Sciences (with a primary mission of research), and The Division of Pharmaceutical Services (with a primary mission of clinical care). The department is also home to the licensed Clinical Pharmacokinetics and Therapeutic Drug Monitoring Laboratory, which facilitates measurement of drug levels in every patient at St. Jude, providing an invaluable resource for optimizing drug therapy. Additionally, the Department houses the Cancer Center’s Pharmacokinetics Shared Resource - centralizing high-quality pharmacokinetic/pharmacodynamic clinical research.

Our vision is to be a premier academic department in pharmacy and pharmaceutical sciences, encompassing clinical pharmaceutical care and research, with special expertise in therapeutics relevant for children with catastrophic diseases. Survival rates for children with cancer, hematologic disorders, HIV infection, or other serious diseases continue to increase, largely through the improved use of medications. Failure of current therapies and unacceptable adverse effects are in part due to suboptimal use of medications. Our goal is to elucidate the biological basis of interindividual differences in pharmacologic response, to translate our findings into more rational therapeutics, and to improve patient care by ensuring safe, effective, and rational use of medications. We continue to look for the next technological advancement and new, sophisticated, questions to drive our work forward and improve patient care.

Divisions

Annual Report

Strategic Plan FY25-28

Leadership

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    P. David Rogers, PharmD, PhD, FCCP

    Member, St. Jude Faculty

    Chair, Department of Pharmacy and Pharmaceutical Sciences

    St. Jude Endowed Chair in Pharmaceutical Sciences

    P. David Rogers, PharmD, PhD, FCCP

    Member, St. Jude Faculty

    Chair, Department of Pharmacy and Pharmaceutical Sciences

    St. Jude Endowed Chair in Pharmaceutical Sciences

    Research Interests

    • Improvement of antifungal pharmacotherapy
    • Understanding the molecular and genetic basis of antifungal drug resistance

    Contact Information

    P. David Rogers, PharmD, PhD, FCCP

    Pharmacy and Pharmaceutical Sciences

    MS 313, Room I5112

    St. Jude Children's Research Hospital

    262 Danny Thomas Place

    Memphis, TN 38105-3678

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    Jun J. Yang, PhD

    Member, St. Jude Faculty

    Division Director, Pharmacy Sciences

    Vice-Chair, Department of Pharmacy and Pharmaceutical Sciences

    Endowed Chair in Pharmacogenomics

    Jun J. Yang, PhD

    Member, St. Jude Faculty

    Division Director, Pharmacy Sciences

    Vice-Chair, Department of Pharmacy and Pharmaceutical Sciences

    Endowed Chair in Pharmacogenomics

    Research Interests

    • Understanding the genetic basis of inter-patient variability in anticancer drug response 
    • Pharmacogenomics of anti-leukemia drug toxicities
    • Genomics of anti-leukemia drug sensitivity and resistance (especially molecularly targeted therapeutics)

    Contact Information

    Jun J. Yang, PhD

    Pharmacy and Pharmaceutical Sciences

    MS 313, Room I5104

    St. Jude Children's Research Hospital

    262 Danny Thomas Place

    Memphis, TN 38105-3678

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    M. Brooke Beavers Bernhardt, PharmD, MS, FCCP, BCOP, BCPPS

    Associate Member, St. Jude Faculty

    Chief Pharmacy Officer

    Division Director, Pharmacy Services

    Associate Professor, St. Jude Graduate School of Biomedical Sciences

    M. Brooke Beavers Bernhardt, PharmD, MS, FCCP, BCOP, BCPPS

    Associate Member, St. Jude Faculty

    Chief Pharmacy Officer

    Division Director, Pharmacy Services

    Associate Professor, St. Jude Graduate School of Biomedical Sciences

    Research Interests

    • Pharmacogenomics of treatment-related toxicity and outcomes in pediatric cancer
    • Novel drug development and therapeutic repurposing in pediatric oncology and hematology
    • Epidemiology and population sciences in pediatric oncology and hematology
    • Pharmacoeconomics and outcomes research

    Contact Information

    M. Brooke Beavers Bernhardt, PharmD, MS, FCCP, BCOP, BCPPS

    Pharmacy & Pharmaceutical Sciences

    MS 150, Room C1300

    St. Jude Children's Research Hospital

    262 Danny Thomas Place

    Memphis, TN 38105-3678

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    Steve Pate, DPh

    Director, Outpatient Pharmaceutical Services

    Pharmaceutical Compliance Officer

    Steve Pate, DPh

    Director, Outpatient Pharmaceutical Services

    Pharmaceutical Compliance Officer

    Clinical Interests

    • Outpatient Pharmaceutical Services
    • Compliance
    • Revenue Cycle
    • 340B Program

    Contact Information

    Steve Pate, DPh

    Pharmacy and Pharmaceutical Sciences

    St. Jude Children's Research Hospital

    262 Danny Thomas Place

    Memphis, TN 38105-3678

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    Markos Leggas, PhD

    Member, St. Jude Faculty

    Director, Center for Translational Pharmacology

    Markos Leggas, PhD

    Member, St. Jude Faculty

    Director, Center for Translational Pharmacology

    Research Interests

    • Pharmacometabolomic methods to improve therapeutic outcomes and minimize toxicity in the context of pediatric clinical trials
    • Pharmacometric and systems pharmacology approaches to enable drug development and guide therapy
    • Development of transcription factor pharmacologic inhibitors
    • Biomarkers and treatment of neonatal opioid withdrawal syndrome

    Contact Information

    Markos Leggas, PhD

    Pharmacy and Pharmaceutical Sciences

    MS 313, Room I5104

    St. Jude Children's Research Hospital

    262 Danny Thomas Place

    Memphis, TN 381053678

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    Alejandro R. Molinelli, PhD

    Director, Clinical Pharmacokinetics Laboratory

    Alejandro R. Molinelli, PhD

    Director, Clinical Pharmacokinetics Laboratory


Join us

St. Jude investigators have the freedom to focus on making big discoveries, backed by extraordinary resources and support teams. We are always looking for highly motivated scientists and engineers with passion and talent to join us!

Explore career opportunities in Pharmacy and Pharmaceutical Sciences

We are currently recruiting!

Contact Us

Department of Pharmacy and Pharmaceutical Sciences
MS 313, Room I5112
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN  38105-3678 USA

Email: dave.rogers@stjude.org
Phone: (901) 595-7516
Fax: (901) 595-3125