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Explore our cutting edge research, world-class patient care, career opportunities and more.
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Providing cutting-edge microbial computational genomics and bioinformatics services by exploiting large-scale genomic and omics datasets
The Microbial Computational Genomics Collaborative Center provides and maintains a wide range of analytical services to support researchers. Our team is staffed with computational scientists with analysis expertise in cutting-edge microbial omics and bioinformatics research.
Areas of expertise
The Microbial Computational Genomics Collaborative Center offers cutting-edge microbial genomics and bioinformatics support to help researchers address relevant biological questions. The center fosters collaborations between computational, clinical and experimental sciences to understand host-microbe interactions and how these interactions contribute to disease. Our work spans all stages of microbial research including study design, data management, quality control, routine data processing, customized analysis, interpretation and dissemination of findings.
Routine and customized processing, analysis and interpretation of next-gen sequencing and omics datasets
Assist in coordinating bioinformatics projects involving multiple stakeholders
Assistance with planning and design of bioinformatics projects
Individual and group-based bioinformatics training sessions
Dr. Chrispin Chaguza obtained a BS in Computer Science and Statistics from the University of Malawi in Malawi and an MS in Bioinformatics and Systems Biology from the University of Manchester. He obtained a PhD in Microbial Genomics and Bioinformatics from the University of Liverpool, working with Drs. Stephen Bentley, Dean Everett, and William Hanage. Dr. Chaguza continued his work in bacterial population genomics as a postdoctoral fellow under the mentorship of Dr. Stephen Bentley at the Wellcome Sanger Institute and Darwin College, University of Cambridge. Following his tenure in Cambridge, UK, he completed a second postdoctoral fellowship and a research faculty position at the Yale School of Public Health, under the mentorship of Dr. Nathan Grubaugh and, subsequently, Dr. Daniel Weinberger. At Yale, he focused on viral and bacterial genomics, evolution, and epidemiology. Dr. Chaguza has held several honorary senior research fellowships at the University College London and the University of Liverpool and was an affiliate faculty member at the Yale Institute of Global Health.
As Director of the Microbial Computational Genomics Collaborative Center, he assists investigators in applying microbial genomics and bioinformatics to understand how microbes evolve, spread, and interact with human and animal hosts to cause disease.
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Qidong Jia, PhD
Senior Bioinformatics Research Scientist
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Niru Shanbhag
Bioinformatics Analyst
Chrispin Chaguza, PhD
Department of Host Microbe Interactions
MS 221, Room D1034H
St. Jude Children’s Research Hospital