About the department

Infectious diseases are the leading cause of death in children worldwide. To better understand the process of infection, advance cures and improve prevention strategies, St. Jude established the Department of Host-Microbe Interactions (HMI) in 2023. The HMI’s mission is to drive the creation of knowledge that solves evolving challenges in infection biology through scientific partnerships, education and discovery.

Led by Victor J. Torres, PhD, HMI leverages multidisciplinary research with close institutional collaborations with the Department of Infectious Diseases and other basic science departments to be at the forefront of discovery in infection biology. 



Host-Microbe Interactions Faculty

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    Salvador Almagro-Moreno, PhD

    Associate Member, St. Jude Faculty

    Salvador Almagro-Moreno, PhD

    Associate Member, St. Jude Faculty

    Research Interests

    • Emergence and evolution of bacterial pathogens
    • Cholera and other enteric diseases
    • Virulence regulation and host colonization dynamics
    • Septicemia-causing emerging pathogens
    • Environmental drivers of disease transmission 

    Contact Information

    Salvador Almagro-Moreno, PhD

    Department of Host-Microbe Interactions

    MS 221, Room DT2038C

    St. Jude Children's Research Hospital

    262 Danny Thomas Place

    Memphis, TN 38105-3678

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    Jeremy Chase Crawford, PhD

    Assistant Member, St. Jude Faculty

    Jeremy Chase Crawford, PhD

    Assistant Member, St. Jude Faculty

    Research Interests

    • Integrative Biology
    • Translational immunology, immunotherapy, and immunoinformatics
    • Development of next-generation and multi-omic molecular methods
    • Childhood immune development
    • Immune perturbations from disease and treatment
    • Host-pathogen interactions

    Contact Information

    Jeremy Chase Crawford, PhD

    Department of Host-Microbe Interactions

    MS 221

    St. Jude Children's Research Hospital

    262 Danny Thomas Place

    Memphis, TN 38105-3678

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    Bradley Muller, MD

    Instructor, St. Jude Faculty

    Bradley Muller, MD

    Instructor, St. Jude Faculty

    Contact Information

    Bradley Muller, MD

    St. Jude Children's Research Hospital

    262 Danny Thomas Place

    Memphis, TN 38105-3678

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    Jason W. Rosch, PhD

    Member, St. Jude Faculty

    Jason W. Rosch, PhD

    Member, St. Jude Faculty

    Research Interests

    • Understanding host-pathogen interactions in Streptococcus pneumoniae
    • Modeling complex respiratory infections and their role in disease and transmission
    • Development of novel vaccine strategies for respiratory infections
    • Modeling antibiotic resistance mechanisms in Streptococcus pneumoniae
    • Understanding the role of high-risk hosts in infection susceptibility and antibiotic resistance development

    Contact Information

    Jason W. Rosch, PhD

    Host-Microbe Interactions

    MS 320, Room E8055

    St. Jude Children's Research Hospital

    262 Danny Thomas Place

    Memphis, TN 38105-3678

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    Stacey L. Schultz-Cherry, PhD

    Member, St. Jude Faculty

    Deputy Director, World Health Organization Collaborating Centre for Studies on the Ecology of Influenza in Animals and Birds

    Senior Associate Dean, Student and Faculty Affairs

    Stacey L. Schultz-Cherry, PhD

    Member, St. Jude Faculty

    Deputy Director, World Health Organization Collaborating Centre for Studies on the Ecology of Influenza in Animals and Birds

    Senior Associate Dean, Student and Faculty Affairs

    Research Interests

    • Influenza virus pathogenesis
    • Astrovirus pathogenesis
    • Novel vaccines and therapeutics
    • Microbial co-infections

    Short Biography

    Stacey Schultz-Cherry, PhD is a Full Member (Professor) in the Department of Host-Microbe Interactions at St Jude Children’s Research Hospital in Memphis, TN where she serves as the Co-Director for the NIAID-funded Center for Excellence in Influenza Research and Response (CEIRR) and Co-Director for the NIAID-funded Collaborative Influenza Vaccine Innovation Center (CIVIC). She received her PhD in Molecular and Cellular Pathology from the University of Alabama at Birmingham and did postdoctoral training in influenza virology at the University of Wisconsin. Before joining the faculty at St Jude Children’s Research Hospital in 2009, she was a tenured Associate Professor in the Department of Medical Microbiology and Immunology at the University of Wisconsin-Madison. Dr. Schultz-Cherry is recognized internationally for her studies on the pathogenesis influenza and enteric viruses in high risk populations and influenza at the animal-human interface. Dr. Schultz-Cherry is the author and co-author of over 200 research articles, reviews and book chapters, is the past President of the American Society for Virology, and the current chair of the Public and Scientific Affairs Committee for the American Society for Microbiology (ASM). 

    Contact Information

    Stacey L. Schultz-Cherry, PhD

    Host-Microbe Interactions

    MS 320, Room E8053

    St. Jude Children's Research Hospital

    262 Danny Thomas Place

    Memphis, TN 38105-3678

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    Victor J. Torres, PhD

    Member, St. Jude Faculty

    Chair, Host-Microbe Interactions

    Victor J. Torres, PhD

    Member, St. Jude Faculty

    Chair, Host-Microbe Interactions

    Research Interests

    • Host-pathogen interactions
    • Staphylococcus aureus biology
    • Toxin biology
    • Development of novel therapeutics against multidrug resistant pathogens

    Short Biography

    Dr. Victor J. Torres joined St. Jude in 2023 as the founding Chair of the Department of Host-Microbe Interactions. Previously, he founded and directed the Antimicrobial-Resistant Pathogens Program at NYU Grossman School of Medicine while also serving as the C.V. Starr Professor of Microbiology. Over the last 15 years, Torres has worked closely with industrial partners to translate his discoveries on Staphylococcus aureus virulence mechanisms into candidate vaccines and biologics. In 2023, Torres founded CIDR as a vehicle to accelerate research in catastrophic pediatric infectious diseases at St. Jude.

    Contact Information

    Victor J. Torres, PhD

    Host-Microbe Interactions

    MS 221, Room D2038D

    St. Jude Children's Research Hospital

    262 Danny Thomas Place

    Memphis, TN 38105-3678

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    Elaine I. Tuomanen, MD

    Member, St. Jude Faculty

    Elaine I. Tuomanen, MD

    Member, St. Jude Faculty

    Research Interests

    • Molecular pathogenesis of Streptococcus pneumoniae invasion and inflammation
    • Gram-positive molecular biology and genomics
    • Gram-positive interactions with human cells and models of disease
    • Novel antibiotic development strategies and pneumococcal vaccine design
    • Antibiotic resistance 

    Contact Information

    Elaine I. Tuomanen, MD

    Host-Microbe Interactions

    MS 221, Room DT2058F

    St. Jude Children's Research Hospital

    262 Danny Thomas Place

    Memphis, TN 38105-3678

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    Richard Webby, PhD

    Member, St. Jude Faculty

    Director, World Health Organization Collaborating Centre for Studies on the Ecology of Influenza in Animals and Birds

    Richard Webby, PhD

    Member, St. Jude Faculty

    Director, World Health Organization Collaborating Centre for Studies on the Ecology of Influenza in Animals and Birds

    Research Interests

    • Influenza virus ecology
    • Influenza vaccination
    • Influenza virus pathogenicity
    • Determinants of host susceptibility to influenza

    Contact Information

    Richard Webby, PhD

    Host-Microbe Interactions

    MS 330, Room I6301

    St. Jude Children's Research Hospital

    262 Danny Thomas Place

    Memphis, TN 38105-3678

Department at a glance

Collaborative Centers

HMI utilizes a myriad of scientific approaches to study the complex interactions between microbes and their host. These include techniques from microbiology, virology, immunology, biochemistry, chemical biology, structural biology and computational biology. HMI hosts several state-of-the-art collaborative centers.. Together with shared resources and core facilities, we are realizing our mission to tackle catastrophic infectious diseases.


Department team

Victor J. Torres, PhD
Chair, Department of Host-Microbe Interactions 
Director, Center for Infectious Diseases Research
Albert and Rosemary Joseph Endowed Chair in Host-Microbe Interactions

Richard J. Webby, PhD
Director, WHO Collaborating Center for Studies on the Ecology of Influenza in Animals and Birds
Co-Director, St. Jude Center of Excellence for Influenza Research and Response

Stacey L. Schultz-Cherry, PhD
Deputy Director, WHO Collaborating Center for Studies on the Ecology of Influenza in Animals and Birds
Co-Director, St. Jude Center of Excellence for Influenza Research and Response
Co-Director, St. Jude Center of Excellence for Influenza Research and Response

Paul G. Thomas, PhD
Leader of the TIRTL Bluesky Initiative

Shelly Burrow
Administrative Director

Joel Otero, PhD
Director, Research Operations

Tracy White
Sr Administrative Coordinator

Charles Ferryman
Grants and Contracts Administrator 

Ashley L. DuMont, PhD
Scientific Writer

Julian D. Earl
Program Manager

James Knowles
Clinical Research Associate 

Trupti Patel
Sr Administrative Specialist

Shandy Lewis
Sr Administrative Specialist

L'Keyla Holley
Sr Administrative Specialist

Training and Development

HMI faculty are invested in and committed to mentoring and training the next generation of scientists who will push the boundaries of research to solve important questions in the field of infection biology. Weekly work-in-progress meetings and departmental seminars raise the visibility of ongoing work across the member labs and provide opportunities for interaction, feedback, and collaboration with subject matter experts.

Interested in pursuing doctoral training in HMI? St. Jude Children’s Research Hospital offers a degree-granting program from the Graduate School of Biomedical Sciences. Learn how a degree from St. Jude can support your scientific development and make a difference.

St. Jude Children’s Research Hospital also provides an unparalleled opportunity to advance the scientific career of postdoctoral fellows. Interested candidates should apply here or contact individual faculty members. 

Current makeup and future growth

HMI is a new department and is undergoing substantial growth. HMI currently consists of eight individual laboratories and expects to grow to 17 laboratories over the next five years. St. Jude investigators have the freedom to focus on making transformative discoveries backed by extraordinary resources and support teams. We are always seeking highly motivated scientists with passion and talent to join us!

Salvador Almagro-Moreno and Victor Torres

Contact us

Victor J. Torres, PhD, Chair 
Department of Host-Microbe Interactions
Room D2038
St. Jude Children's Research Hospital

262 Danny Thomas Place
Memphis, TN, 38105-3678 USA
victor.torres@stjude.org

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