2021 Archive

Investigator Insights

5 Questions for Cat Willis, PhD

Erin Podolak, MA and Cat Willis, PhD

In the Children’s GMP, LLC, Cat Willis, PhD, is the quality control “gatekeeper” making sure cell products are of the highest quality.

dali-like illustration of clocks in a wasteland
dali-like illustration of clocks in a wasteland
Research

The ticking ‘epigenetic’ clock measures true biological age

Alex Generous, PhD

Dive into research on the ‘epigenetic clock’ and learn how understanding it can help childhood cancer survivors.

Artistic rendering of a palliative care specialist interacting with a patient to improve their quality of life
Artistic rendering of a palliative care specialist interacting with a patient to improve their quality of life
Outreach

Global effort improves patients’ quality of life through palliative care

Alex Generous, PhD

St. Jude is collaborating to expand access to palliative care worldwide. 

Charles Mullighan
Charles Mullighan
Clinical

Blinatumomab added to chemotherapy improves survival for adults with acute lymphoblastic leukemia

Alex Generous, PhD

St. Jude scientists contributed to a phase 3 clinical trial showing that blinatumomab added to chemotherapy is effective against leukemia in adults.

Two people in white coats examining a slide.
Two people in white coats examining a slide.
Research

Influenza and gene therapy researchers team up to create more effective flu vaccine

Ashley DuMont, PhD

Graduate students team up to design more effective flu vaccine.

Robby Teis
Robby Teis
Investigator Insights

Researching brain tumors to honor his brother’s legacy with Robby Teis

Robby Teis

Watch the video interview with Robby Teis, a student in the St. Jude Graduate School of Biomedical Sciences to learn how his brother’s cancer inspired his current research.

St. Jude On

Universal pneumonia vaccination is the result of decades of research

Alex Generous, PhD

Through decades of research Elaine Tuomanen, MD, made crucial contributions to the creation of the first universal vaccine for pneumonia – now in clinical trials.

Outreach

Advancing careers beyond the bench: the St. Jude CAP Fellowship

Emilia Asante, PhD

See how the CAP Fellowship is emerging as a competitive full-time career training experience for St. Jude postdocs.

St. Jude On

Addressing fungal infections will take a medical mycology moonshot

Brian O'Flynn, PhD

See how St. Jude is working to counteract the rise of antifungal resistance

Research

Like kisMET: targeted therapy and radiation synergize in pediatric high-grade glioma

Erin Podolak, MA

Translational research from Suzanne Baker, PhD, and colleagues shows that targeted MET inhibitor capmatinib effectively crosses the blood-brain-barrier, synergizing with radiation to treat pediatric high-grade glioma.

Lisa Jacola
Lisa Jacola
Research

Pain may be a risk factor for learning problems in childhood cancer survivors

Mary Powers

Researchers are focusing on treatment-related pain as another way to reduce the risk of learning and memory problems in survivors of childhood leukemia.

Lecture series logo
Lecture series logo
Investigator Insights

Rising Stars of Cancer Research lectures to bring fresh insights

Mary Powers

The Rising Stars of Cancer Research program is a new to the Science of Childhood Cancer lecture series. The program highlights the work of emerging leaders in the cancer research community.

global
global
Outreach

St. Jude Global Alliance holds third annual convening

Lance Wiedower

Empower Everyone was the theme of the St. Jude Global Alliance Convening, a virtual meeting that attracted participants from around the world.

CoNGA
CoNGA
Research

CoNGA: Deciphering the dance of T-cell differentiation

Stefan Schattgen, PhD

St. Jude scientists have created an algorithm to help group T-cells by their function by evaluating two different types of data, T-cell receptor sequences and gene expression.

Walter Hughes sits at a desk early in his career
Walter Hughes sits at a desk early in his career
Investigator Insights

St. Jude mourns the death of infectious diseases pioneer Walter Hughes, MD

Mike O’Kelly

Walter Hughes, MD, who established the St. Jude Department of Infectious Diseases and initiated pediatric AIDS research at the hospital, has died.

Haitao Pan, PhD
Haitao Pan, PhD
Research

St. Jude biostatisticians create a novel clinical trial design software

St. Jude Progress

St. Jude biostatisticians have developed a new method for designing phase 2 clinical trials with a small sample size. The approach uses a mathematical model called Bayesian probability . The researchers created free software to implement the process.

Meeting graphic
Meeting graphic
Research

Bringing Chemistry to Medicine: Transcription therapy symposium is set for July 22 and 23

Mike O’Kelly

St. Jude will host the virtual Bringing Chemistry to Medicine Symposium July 22–23. The inaugural event in 2020 prompted a researcher in India to become a visiting scientist at St. Jude. Register for the event.

image of matches with one burnt in the middle
image of matches with one burnt in the middle
Clinical

When work takes a toll: St. Jude research adds to our understanding of physician burnout.

Jonathan Burlison and Lindsay Blazin

St. Jude researchers looked at burnout and perceived work demands among St. Jude physicians and found that emotional exhaustion and time demands are key factors in a problem that affects both provider and patient.

Stronger Together
Stronger Together
Investigator Insights

Connections with colleagues: A St. Jude pediatric psychologist has renewed appreciation for an overlooked benefit of interdisciplinary collaboration.

Elyse Heidelberg, PsyD

A pediatric psychologist expresses gratitude for interdisciplinary collaboration, which elevates patient care and provider well-being.

Martine Roussel, PhD, stands for a portrait with her lab blurred out in the background.
Martine Roussel, PhD, stands for a portrait with her lab blurred out in the background.
Investigator Insights

Roussel’s early discovery shaped a career of cancer research

St. Jude Communications Department

Martine Roussel, PhD, faculty member and endowed chair in molecular oncogenesis, shares how early work on oncogenes led to her lab’s discovery of new oncogenes.