2021 Archive

Abstract image of a brain in a cave
Abstract image of a brain in a cave
Clinical

Uncovering the source of a “silent” syndrome

Brian O'Flynn, PhD

Discover the neuronal interactions at the center of posterior fossa syndrome

Paul Taylor standing in front of a wood-paneled wall
Paul Taylor standing in front of a wood-paneled wall
Investigator Insights

5 Questions for J. Paul Taylor, MD, PhD

Brian O'Flynn, PhD

Learn how J. Paul Taylor, MD, PhD, leveraged the unique infrastructure at St. Jude to launch the Pediatric Translational Neuroscience Initiative

Four women talk in front of screen
Four women talk in front of screen
Research

Distinct molecular profiles lead to a better understanding of acute leukemia

Emilia Asante, PhD

Distinct molecular profiles in acute myeloid leukemia (AML) and T-cell acute lymphoblastic leukemia/lymphoma (T-ALL/LLy) with PICALM::MLLT10 (PM) fusions shed light on potential targeted therapies for improved outcomes.

Planet Earth in front of a galaxy background with circles surrounding the planet
Planet Earth in front of a galaxy background with circles surrounding the planet
Outreach

Global peer community sets standards to save vulnerable children from infectious diseases

Alex Generous, PhD

St. Jude is helping train and make guidelines to prevent and treat infections during pediatric cancer treatment worldwide.

Doctor talking to patient in hospital room
Doctor talking to patient in hospital room
Clinical

Boot camp trains sickle cell disease ‘pain crises champions’ to improve patient care

Alex Generous, PhD

St. Jude and UTHSC are training nurses worldwide how to better care for people with sickle cell disease.

Research

A glimpse beyond life and death: Exploring the biology of the MICOS complex

Brian O'Flynn, PhD

See how new model offers glimpse into vital mitochondrial complex

image of Sarah Currie
image of Sarah Currie
Investigator Insights

Core values underlie nursing excellence

Sarah Currie, RNC, MSN, NEA-BC

Learn about the values that shape nursing research and care at St. Jude.

St. Jude On

Addressing the needs of childhood cancer survivors

Brian O'Flynn, PhD

See how many factors from environment to genetics affect the post-treatment experience of childhood cancer survivors

Clinical

Long-acting injectable HIV drugs safe for treating adolescents

Alex Generous, PhD

Learn how long-lasting drugs offer hope for adolescent with HIV.

Image of two people talking
Image of two people talking
St. Jude On

Evaluating care for ‘the forgotten population’: Factors affecting sickle cell care

Kathryn J. McCullough, MA

St. Jude researchers examine factors that affect access to care for patients with sickle cell disease.

Lisa Jacola
Lisa Jacola
Research

Pain may be a risk factor for learning problems in childhood cancer survivors

Mary Powers

Researchers are focusing on treatment-related pain as another way to reduce the risk of learning and memory problems in survivors of childhood leukemia.

Lecture series logo
Lecture series logo
Investigator Insights

Rising Stars of Cancer Research lectures to bring fresh insights

Mary Powers

The Rising Stars of Cancer Research program is a new to the Science of Childhood Cancer lecture series. The program highlights the work of emerging leaders in the cancer research community.

global
global
Outreach

St. Jude Global Alliance holds third annual convening

Lance Wiedower

Empower Everyone was the theme of the St. Jude Global Alliance Convening, a virtual meeting that attracted participants from around the world.

CoNGA
CoNGA
Research

CoNGA: Deciphering the dance of T-cell differentiation

Stefan Schattgen, PhD

St. Jude scientists have created an algorithm to help group T-cells by their function by evaluating two different types of data, T-cell receptor sequences and gene expression.

Walter Hughes sits at a desk early in his career
Walter Hughes sits at a desk early in his career
Investigator Insights

St. Jude mourns the death of infectious diseases pioneer Walter Hughes, MD

Mike O’Kelly

Walter Hughes, MD, who established the St. Jude Department of Infectious Diseases and initiated pediatric AIDS research at the hospital, has died.

Haitao Pan, PhD
Haitao Pan, PhD
Research

St. Jude biostatisticians create a novel clinical trial design software

St. Jude Progress

St. Jude biostatisticians have developed a new method for designing phase 2 clinical trials with a small sample size. The approach uses a mathematical model called Bayesian probability . The researchers created free software to implement the process.

Meeting graphic
Meeting graphic
Research

Bringing Chemistry to Medicine: Transcription therapy symposium is set for July 22 and 23

Mike O’Kelly

St. Jude will host the virtual Bringing Chemistry to Medicine Symposium July 22–23. The inaugural event in 2020 prompted a researcher in India to become a visiting scientist at St. Jude. Register for the event.

image of matches with one burnt in the middle
image of matches with one burnt in the middle
Clinical

When work takes a toll: St. Jude research adds to our understanding of physician burnout.

Jonathan Burlison and Lindsay Blazin

St. Jude researchers looked at burnout and perceived work demands among St. Jude physicians and found that emotional exhaustion and time demands are key factors in a problem that affects both provider and patient.

Stronger Together
Stronger Together
Investigator Insights

Connections with colleagues: A St. Jude pediatric psychologist has renewed appreciation for an overlooked benefit of interdisciplinary collaboration.

Elyse Heidelberg, PsyD

A pediatric psychologist expresses gratitude for interdisciplinary collaboration, which elevates patient care and provider well-being.

Martine Roussel, PhD, stands for a portrait with her lab blurred out in the background.
Martine Roussel, PhD, stands for a portrait with her lab blurred out in the background.
Investigator Insights

Roussel’s early discovery shaped a career of cancer research

St. Jude Communications Department

Martine Roussel, PhD, faculty member and endowed chair in molecular oncogenesis, shares how early work on oncogenes led to her lab’s discovery of new oncogenes.