2021 Archive

Research

Laying the foundation for neuronal development

Brian O'Flynn, PhD

See how blocking one kinase resulted in premature neuron growth

Investigator Insights

5 Questions for Renato Umeton, PhD

Renato Umeton, PhD and Alex Generous, PhD

Meet St. Jude Chief of AI Renato Umeton, PhD, Office of Data Science.

Outreach

Working globally to save critically ill children with cancer

LaToyia P. Downs, PhD

The Global Critical Care Program is advancing critical care for children with cancer worldwide through innovation, collaboration and education.

Investigator Insights

5 Questions for Anand Kulkarni, PhD

Erin Podolak, MA and Anand Kulkarni, PhD

Learn what associate scientist Anand Kulkarni, PhD, thinks makes doing research at St. Jude different from anywhere else.

Clinical

Research findings set the stage for GLOBOTRK, a clinical trial with targeted therapy for NTRK and ROS1 fusions

Alex Generous, PhD

St. Jude is leading a global clinical trial for brain tumors.

Investigator Insights

5 Questions for Janeala Morsby, PhD

Erin Podolak, MA and Janeala Morsby, PhD

Meet postdoctoral researcher Janeala Morsby, PhD, Department of Oncology and learn about her research.

Clinical

Patient voices shape the future of gene therapy

Alex Generous, PhD

Learn what patients, families and health care workers think about gene therapy.

Investigator Insights

5 Questions for Priyanka Dogra, PhD

Priyanka Dogra, PhD and Erin Podolak, MA

Meet postdoctoral researcher Priyanka Dogra, PhD, Department of Structural Biology, and learn about her research.  

Clinical

Hydroxyurea may help kids with sickle cell disease breathe better at night

Alex Generous, PhD

Find how sickle cell treatment may help kids get better sleep.

Investigator Insights

5 Questions for Maowei Hu, PhD

Maowei Hu and Erin Podolak, MA

Meet postdoctoral researcher Maowei Hu, PhD, Department of Chemical Biology & Therapeutics and learn about her research.  

Research

Pain may be a risk factor for learning problems in childhood cancer survivors

Mary Powers

Researchers are focusing on treatment-related pain as another way to reduce the risk of learning and memory problems in survivors of childhood leukemia.

Investigator Insights

Rising Stars of Cancer Research lectures to bring fresh insights

Mary Powers

The Rising Stars of Cancer Research program is a new to the Science of Childhood Cancer lecture series. The program highlights the work of emerging leaders in the cancer research community.

Outreach

St. Jude Global Alliance holds third annual convening

Lance Wiedower

Empower Everyone was the theme of the St. Jude Global Alliance Convening, a virtual meeting that attracted participants from around the world.

Research

CoNGA: Deciphering the dance of T-cell differentiation

Stefan Schattgen, PhD

St. Jude scientists have created an algorithm to help group T-cells by their function by evaluating two different types of data, T-cell receptor sequences and gene expression.

Investigator Insights

St. Jude mourns the death of infectious diseases pioneer Walter Hughes, MD

Mike O’Kelly

Walter Hughes, MD, who established the St. Jude Department of Infectious Diseases and initiated pediatric AIDS research at the hospital, has died.

Research

St. Jude biostatisticians create a novel clinical trial design software

St. Jude Progress

St. Jude biostatisticians have developed a new method for designing phase 2 clinical trials with a small sample size. The approach uses a mathematical model called Bayesian probability . The researchers created free software to implement the process.

Research

Bringing Chemistry to Medicine: Transcription therapy symposium is set for July 22 and 23

Mike O’Kelly

St. Jude will host the virtual Bringing Chemistry to Medicine Symposium July 22–23. The inaugural event in 2020 prompted a researcher in India to become a visiting scientist at St. Jude. Register for the event.

Clinical

When work takes a toll: St. Jude research adds to our understanding of physician burnout.

Jonathan Burlison and Lindsay Blazin

St. Jude researchers looked at burnout and perceived work demands among St. Jude physicians and found that emotional exhaustion and time demands are key factors in a problem that affects both provider and patient.

Investigator Insights

Connections with colleagues: A St. Jude pediatric psychologist has renewed appreciation for an overlooked benefit of interdisciplinary collaboration.

Elyse Heidelberg, PsyD

A pediatric psychologist expresses gratitude for interdisciplinary collaboration, which elevates patient care and provider well-being.

Investigator Insights

Roussel’s early discovery shaped a career of cancer research

St. Jude Communications Department

Martine Roussel, PhD, faculty member and endowed chair in molecular oncogenesis, shares how early work on oncogenes led to her lab’s discovery of new oncogenes.