2021 Archive

Immunotherapy

Innovation propels an immunotherapy ‘growth spurt’

Kathryn J. McCullough, MA

Discover how CAR T–cell therapy led to a growth spurt for both Alfonso and the immunotherapy program at St. Jude.

St. Jude On

Prioritizing psychosocial care in the treatment of pediatric catastrophic disease

Kathryn J. McCullough, MA

Learn how St. Jude is prioritizing psychosocial care in the treatment of pediatric catastrophic disease.

Research

Parallel analysis method cracks scalable single-molecule imaging

Alex Generous, PhD

Clever engineering widens researchers’ view of the single-molecule scale.

St. Jude On

Why biology demands a different playbook for kids with cancer

Kasey Belanger-Mayer, PhD

Hear from Charles W.M. Roberts, MD, PhD, on why pediatric cancers are distinct from their adult counterparts – needing their own research and treatments.

Global Health

Helping childhood cancer go from invisible to a public health priority in Ecuador

Matt Gaschk

The Global Platform for Access to Childhood Cancer Medicines is raising the profile of childhood cancer and how best to treat it in Ecuador.

Profiles

5 Questions for Julia Hanebrink, PhD

Taylor Wewel and Julia Hanebrink

Discover how a background in anthropology influences how clinical research scientist Julia Hanebrink, PhD, approaches qualitative research.

Clinical

Collaboration eases the way for immunotherapies to move from lab to clinic

Alex Generous, PhD

A unique St. Jude initiative is accelerating clinical CAR–T cell research in a lab-to-clinic-to-lab loop.

Research

Biostatisticians make clinical trial data more dynamic to gain deeper insights

Alex Generous, PhD

Find how a new statistical package is getting more out of trial analysis.

Outreach

Piecing together sustainable care for children with brain tumors worldwide

LaToyia P. Downs, PhD

Learn how global partnerships are improving diagnosis, treatment and care for children with central nervous system tumors in resource-limited countries.

Investigator Insights

St. Jude dentists protect patients’ smiles during and after treatment

Martha Wells, DMD, MS

Meet Martha Wells, DMD, MS, Chief of Dentistry at St. Jude, and learn the importance of dental health in cancer treatment

Research

Pain may be a risk factor for learning problems in childhood cancer survivors

Mary Powers

Researchers are focusing on treatment-related pain as another way to reduce the risk of learning and memory problems in survivors of childhood leukemia.

Profiles

Rising Stars of Cancer Research lectures to bring fresh insights

Mary Powers

The Rising Stars of Cancer Research program is a new to the Science of Childhood Cancer lecture series. The program highlights the work of emerging leaders in the cancer research community.

Global Health

St. Jude Global Alliance holds third annual convening

Lance Wiedower

Empower Everyone was the theme of the St. Jude Global Alliance Convening, a virtual meeting that attracted participants from around the world.

Developmental Biology

CoNGA: Deciphering the dance of T-cell differentiation

Stefan Schattgen, PhD

St. Jude scientists have created an algorithm to help group T-cells by their function by evaluating two different types of data, T-cell receptor sequences and gene expression.

Profiles

St. Jude mourns the death of infectious diseases pioneer Walter Hughes, MD

Mike O’Kelly

Walter Hughes, MD, who established the St. Jude Department of Infectious Diseases and initiated pediatric AIDS research at the hospital, has died.

Research

St. Jude biostatisticians create a novel clinical trial design software

St. Jude Progress

St. Jude biostatisticians have developed a new method for designing phase 2 clinical trials with a small sample size. The approach uses a mathematical model called Bayesian probability . The researchers created free software to implement the process.

Research

Bringing Chemistry to Medicine: Transcription therapy symposium is set for July 22 and 23

Mike O’Kelly

St. Jude will host the virtual Bringing Chemistry to Medicine Symposium July 22–23. The inaugural event in 2020 prompted a researcher in India to become a visiting scientist at St. Jude. Register for the event.

Clinical Research

When work takes a toll: St. Jude research adds to our understanding of physician burnout.

Jonathan Burlison and Lindsay Blazin

St. Jude researchers looked at burnout and perceived work demands among St. Jude physicians and found that emotional exhaustion and time demands are key factors in a problem that affects both provider and patient.

Profiles

Connections with colleagues: A St. Jude pediatric psychologist has renewed appreciation for an overlooked benefit of interdisciplinary collaboration.

Elyse Heidelberg, PsyD

A pediatric psychologist expresses gratitude for interdisciplinary collaboration, which elevates patient care and provider well-being.

Profiles

Roussel’s early discovery shaped a career of cancer research

St. Jude Communications Department

Martine Roussel, PhD, faculty member and endowed chair in molecular oncogenesis, shares how early work on oncogenes led to her lab’s discovery of new oncogenes.