2024 Archive

Outreach

Building blocks: St. Jude Global guides reestablishment of health care capacity during crisis

Erin Podolak, MA

St. Jude Global helps provide a framework for rebuilding health care capacity after a crisis.

Research

Finding the big-TIME players holding back CAR T–cell therapy for high-grade gliomas

Alex Generous, PhD

Explore how tumor-associated macrophages shape CAR T-cell therapy efficacy in high-grade gliomas.

Investigator Insights

5 Questions for Alaa Refaat

Erin Podolak, MA and Alaa Refaat, PhD

Meet St. Jude senior scientist Alaa Refaat, PhD, and learn about his work to develop treatments for childhood brain tumors using chemical biology approaches.

(L to R) First author Prahalathan Pichavaram, PhD, corresponding author Andrew Murphy, MD, St. Jude Department of Surgery and co-author Carolyn Jablonowski, PhD.

Research

Ribosome production presents a new therapeutic opportunity against Wilms tumor

Alex Generous, PhD

Discover how disruption ribosomes creation provides promise for “undruggable” cancers.

Outreach

St. Jude Mentorship Roundtable

Alex Generous, PhD

Watch scientific mentors discuss the value of mentorship.

Research

Just like the real thing: Synthetic gene expression regulators demonstrate success

Brian O'Flynn, PhD

See how Aseem Ansari's SynGRs target BET proteins, offering potential for treating diseases like Friedreich’s ataxia and advancing BET domain understanding