St. Jude Research

Progress Pulse

Short summaries of scientific findings from across the St. Jude research enterprise.

Strategies for communicating with honesty and hope in uncertain prognostic situations

Discover how patient- and caregiver-derived insights from the RIGHTime study are being used to characterize best practices in patient-centered prognostic conversations.

Sequencing large-scale changes in DNA to detect cancer earlier

Discover how St. Jude scientists improved detection of large structural changes in DNA to identify cancer cells.

Expedited and accurate detection of targeted gene fusions with St. Jude Fuzzion2

Learn about Fuzzion2, the fuzzy pattern-matching program developed to detect targeted gene fusions with speed and accuracy.

Therapy to reduce the risk of relapse after transplantation does not increase the risk of graft-versus-host disease

A retrospective study finds donor lymphocyte infusions after transplant can lower relapse risk without increasing the risk of graft-versus-host disease.

Reducing the risk of cerebellar mutism syndrome through surgical guidelines

Read how surgeons aim to reduce posterior fossa syndrome risk

Global collaboration reduces preventable infections during pediatric cancer treatment

Learn how St. Jude Global Infectious Disease Program partnered with hospitals in Ecuador and Guatemala to reduce preventable infections in pediatric cancer units through local training.

Developmental window explains origin of non-muscle cell pediatric rhabdomyosarcoma

Discover how endothelial progenitors contribute to rhabdomyosarcoma and restrict the disease to childhood.

Model facilitates research on the second most common form of sickle cell disease

Explore new models of HbSC, which recapitulate the disease’s human symptoms and other pathologies, created by St. Jude research to find better treatments.

Study Provides Insights on Asparaginase-Associated Pancreatitis in Pediatric ALL

Explore the risk factors for asparaginase-associated pancreatitis and outcomes of asparaginase rechallenge.

Binding partners and cooperating mutations define NUP98 leukemia subtypes

See how one rearranged gene can lead to multiple leukemia subtypes