Progress Pulse

Curative therapy promotes sustained improvement in sickle cell cardiomyopathy

Explore the results of a post-hematopoietic stem cell transplantation, 36-month cardiac follow up study in children and young adults with sickle cell disease.

IMPAACT 2017/MOCHA end-of-study results publish

Learn about the end-of-trial, week 96 data from the IMPAACT 2017/MOCHA study.

CRISPR-like editing protein flexes DNA cargo to lock on to the right match

See how the transposase TnsB recognizes and prepares transposons for genome cut-and-paste.

Dual-targeting immunotherapy shows 99.2% remission in relapsed childhood leukemia

Explore the largest clinical trial to date for this transformative therapy.

CD19-CAR T cells persist in the cerebrospinal fluid for months after treatment

Discover what the immunotherapy’s persistence promises for improving treatments.

Understanding the impact of loneliness in adolescent childhood cancer survivors

Learn how loneliness impacts adolescent childhood cancer survivors during the transition to survivorship

Cryo-EM reveals mechanism behind transport of a key vascular regulator

Learn how sphingosine-1-phosphate is transported from blood cells to plasma

Mass spectrometry method fixes short-lived protein interactions in place

Learn about PhIX-MS, a new mass spectrometry technique to investigate dynamic protein assemblies.

A newly discovered ATPase regulates magnesium ion levels in the endoplasmic reticulum

Learn how the magnesium ion transporter ERMA maintains free magnesium levels in cells.

Micro-costing analysis reveals pediatric Hodgkin lymphoma treatment costs across resource settings

Learn how pediatric Hodgkin lymphoma treatment costs vary across resource settings.