St. Jude Research

Progress Pulse

Short summaries of scientific findings from across the St. Jude research enterprise.

Study Provides Insights on Asparaginase-Associated Pancreatitis in Pediatric ALL

Explore the risk factors for asparaginase-associated pancreatitis and outcomes of asparaginase rechallenge.

Binding partners and cooperating mutations define NUP98 leukemia subtypes

See how one rearranged gene can lead to multiple leukemia subtypes

Early nutrient availability is a key driver of T-cell exhaustion

See how early nutrient availability influences T-cell exhaustion even in the early stages of T-cell activation.

Staphylococcus aureus natural infection model uncovers how toxins contribute to disease

Learn how using the right scientific model can reveal new areas to investigate for potential therapeutics.

CAR T–cell therapy shows promise for ependymoma though barriers remain

Learn about the early evidence for ependymoma immunotherapy.

Epigenetic age acceleration contributes to long-term metabolic risk in survivors of pediatric cancer

Find why anti-aging treatments may help survivors stay healthy longer.

New models better predict cardiovascular risks in survivors of childhood cancer

Improving risk predictions to help survivors get better care.

RNA plays a minimal role in CTCF transcription factor function

See how transcriptional control is not affected by RNA–CTCF interactions

St. Jude scMINER improves on single-cell data analysis

A new computational tool reveals hidden signals.

Medical tourism study highlights gap between resourced and resource-limited countries

See how medical tourism impacts St. Jude.