Progress Pulse

Reducing the risk of cerebellar mutism syndrome through surgical guidelines

Read how surgeons aim to reduce posterior fossa syndrome risk

Developmental window explains origin of non-muscle cell pediatric rhabdomyosarcoma

Discover how endothelial progenitors contribute to rhabdomyosarcoma and restrict the disease to childhood.

Model facilitates research on the second most common form of sickle cell disease

Explore new models of HbSC, which recapitulate the disease’s human symptoms and other pathologies, created by St. Jude research to find better treatments.

Study Provides Insights on Asparaginase-Associated Pancreatitis in Pediatric ALL

Explore the risk factors for asparaginase-associated pancreatitis and outcomes of asparaginase rechallenge.

Binding partners and cooperating mutations define NUP98 leukemia subtypes

See how one rearranged gene can lead to multiple leukemia subtypes

Early nutrient availability is a key driver of T-cell exhaustion

See how early nutrient availability influences T-cell exhaustion even in the early stages of T-cell activation.

NUTD5 forms the fulcrum of thiopurine toxicity and resistance

Understanding the protein’s role may unlock individual cancer and autoimmune therapies. Progress category: Pulse

Staphylococcus aureus natural infection model uncovers how toxins contribute to disease

Learn how using the right scientific model can reveal new areas to investigate for potential therapeutics.

CAR T–cell therapy shows promise for ependymoma though barriers remain

Learn about the early evidence for ependymoma immunotherapy.

Epigenetic age acceleration contributes to long-term metabolic risk in survivors of pediatric cancer

Find why anti-aging treatments may help survivors stay healthy longer.