Progress Pulse

Short summaries of scientific findings from across the St. Jude research enterprise.

Binding partners and cooperating mutations define NUP98 leukemia subtypes

See how one rearranged gene can lead to multiple leukemia subtypes

Staphylococcus aureus natural infection model uncovers how toxins contribute to disease

Learn how using the right scientific model can reveal new areas to investigate for potential therapeutics.

CAR T–cell therapy shows promise for ependymoma though barriers remain

Learn about the early evidence for ependymoma immunotherapy.

Epigenetic age acceleration contributes to long-term metabolic risk in survivors of pediatric cancer

Find why anti-aging treatments may help survivors stay healthy longer.

New models better predict cardiovascular risks in survivors of childhood cancer

Improving risk predictions to help survivors get better care.

RNA plays a minimal role in CTCF transcription factor function

See how transcriptional control is not affected by RNA–CTCF interactions

St. Jude scMINER improves on single-cell data analysis

A new computational tool reveals hidden signals.

Medical tourism study highlights gap between resourced and resource-limited countries

See how medical tourism impacts St. Jude.

Study sheds light on discussing prognosis in pediatric oncology

See how patients, parents and oncologists prefer to discuss prognosis in advanced pediatric cancer and ways to improve the delivery of prognostic information.

Experimental models reveal possible treatment for alveolar rhabdomyosarcoma

See how leucine metabolism offers hope for high-risk rhabdomyosarcoma