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Research reveals unexpected roles of TEAD proteins in neurodevelopment
05/20/2025
Read new research showing TEAD proteins’ context can drive neural progenitor proliferation or differentiation, revealing risks for targeting these proteins.
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St. Jude scientist Charles Mullighan elected to the Royal Society of London
05/20/2025
Prolific leukemia researcher named a Fellow of the elite 364-year-old British scientific organization selected for his genomic research into childhood ALL.
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Infant immune systems respond differently to severe COVID-19
05/16/2025
Infants show unique immune responses to COVID-19, differing from adults and children. New study may guide better treatments for severe infant infections.
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Study reveals targetable mechanism behind high-risk predisposition gene in pediatric medulloblastoma
05/15/2025
Uncover how ELP1 gene defects drive pediatric brain cancer—and learn how that revealed MDM2 inhibition as a targeted therapy to restore tumor suppressor p53.
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St. Jude neurologist Richard Finkel named to TIME100 Health
05/08/2025
Dr. Richard Finkel, St. Jude Center for Experimental Neurotherapeutics director, recognized by TIME Magazine for influencing global health.
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Researchers crack the code of cell movement
04/23/2025
New research found chemokines & G protein-coupled receptors encode cell migration information in small, disordered regions, and how to alter these proteins.
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Roberts, Zhang receive prestigious appointments at AACR annual meeting
04/22/2025
St. Jude researchers and clinicians to be recognized for achievements in cancer research
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Discovery of FOXR2 activation in various brain tumors refines diagnosis to improve care
04/15/2025
Read research showing activation of oncogene FOXR2 occurs in multiple pediatric central nervous system tumor types, with implications for clinical diagnosis.
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Study provides scaffold to selectively target drug breakdown process
04/10/2025
See how a panel of CYP3A4 inhibitors lay groundwork for selective cytochrome P450 inhibition by avoiding CYP3A5.
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Chromatin remodeling captured in comprehensive structural study
04/02/2025
See how St. Jude scientists used cryo-EM to uncover the structural mechanisms of chromatin remodeling enzyme SNF2H, advancing gene regulation research.
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