St. Jude Family of Websites
Explore our cutting edge research, world-class patient care, career opportunities and more.
St. Jude Children's Research Hospital Home
- Fundraising
St. Jude Family of Websites
Explore our cutting edge research, world-class patient care, career opportunities and more.
St. Jude Children's Research Hospital Home
- Fundraising
Over the past year, we have made substantial progress in achieving our mission. This Scientific Report highlights some of the more notable advancements St. Jude faculty and staff made in 2023. The work described in this report underscores the unique scientific culture at St. Jude and illustrates how it drives our faculty and staff to tackle the most challenging problems and answer the most complex questions.
St. Jude Researchers, backed by extraordinary resources and support teams, are focused on making big discoveries.
Scientific Highlights
- Genomic architecture promotes lentiviral gene therapy success
- Fusion oncoprotein forces cell fates toward rhabdomyosarcoma
- Computational tool targets oncofusions’ weakness
- A new drug target for inflammation
- Pediatric Early Warning Systems save lives in Latin American hospitals
- Gain-of-function mutation reveals new target in pediatric acute myeloid leukemia
- Preventing neurodevelopmental disorders through genetic compensation
- SWI/SNF complexes ‘bookmark’ cell identity during division
- Pharmacotyping provides a precision medicine blueprint for acute lymphoblastic leukemia treatment
- Proton therapy improves neurocognitive outcomes of childhood craniopharyngioma
- Anchoring domain in chimeric antigen receptors improves immunotherapies
- Unraveling predisposition to bilateral Wilms tumor
- A healthy lifestyle may reduce mortality risk in adult survivors
Supporting Content
- Next-generation gene editing for sickle cell disease
- Pediatric Cancer Dependencies Accelerator
- Two new department chairs bring a bold vision to pathogen research
- From conformation to chemistry
- Shared Resources help Elizabeth Kellogg, PhD, take fundamental research to the next level
- Neuro-oncology leaders continue a legacy of excellence
The Full Report
View the 2024 St. Jude Scientific Report as a digital flipbook.