2021 Archive

Pharmaceutical Sciences

Finding the balance between efficacy and toxicity in pediatric cancer treatment

Alex Generous, PhD

Discover how researchers find ways to improve treatments with genetic information.

Outreach

St. Jude affirms commitment to global childhood health at United Nations General Assembly

Lance Wiedower

The work of St. Jude Global was on display at the 80th session of the United Nations General Assembly.

Pharmaceutical Sciences

The circuitous path from chemical compound to clinical trial

Heather Johnson

St. Jude scientists are making progress in the treatment of pediatric cancer by translating new drug findings from the lab to the clinic.

Profiles

5 Questions for Andrew Kleist, MD, PhD

Andrew Kleist, MD, PhD and Alex Generous, PhD

Meet Andew Kleist, MD, PhD, a 2025 STAT Wunderkind early career scientist.

Research

Genomic Medicine Initiative (GEMINI) targets unmet needs in rare disease treatment

Jake Hopkins, MBA and Brian O'Flynn, PhD

Learn how GEMINI addresses the challenges of rare genetic diseases

Profiles

Navigating a non-traditional path to becoming a scientist

Matthew Fisher

Meet graduate student Matthew Fisher to learn about his atypical scientific career progression.

Survivorship

St. Jude calculators crunch the numbers to empower survivors of childhood cancer

Alex Generous, PhD

Find about these free resources, which scientists keep current with the most current survivorship research.

Profiles

Finding my path from baseball to biomedical science

Jordan Bondrowski

A chance encounter at a baseball game as a child set Jordan Bondrowski on the path toward becoming a student in the St. Jude Graduate School of Biomedical Sciences.

Research

Demystifying a methylation mystery at the fetal hemoglobin gene promoter

Alex Generous, PhD

Learn how St. Jude scientists answered a decades-old mystery with implications for sickle cell anemia and beta thalassemia treatment.

Imaging

Harnessing the power of PET to diagnose infectious disease

Kathryn J. McCullough, MA

In a first-in-human trial, investigators at St. Jude are using the power of PET paired with novel radiotracer, [18F]fluoromannitol, to diagnose bacterial infections in patients.

Sickle Cell

The global burden of sickle cell disease: The quality of treatment shouldn’t depend upon where you live

Ayobami Olanrewaju, MD

Survival and quality of life for many with sickle cell disease depends upon where they live. Here’s what a doctor wants to do to fix that.

Clinical

How do fathers grieve the loss of a child?

Michael J. McNeil, MD

Fathers express grief through keeping busy or focusing on work – different than a mother’s grief. But fathers may not be getting the support they need after the loss of a child.

Profiles

A career of service to those in need

Katy Hobgood

Nehali Patel, MD, grew up helping those in need. Read how working with HIV-infected children has shaped her medical career.

Vaccinations

The path to cancer prevention includes HPV vaccination

Heather Brandt, PhD

There’s a global push to increase HPV vaccination rates, and if successful, there are these future benefits everyone can enjoy.

Profiles

A blend of art and math inspires Hankins’ science

Elizabeth Whittington

St. Jude highlights Jane Hankins, who offers insights into how the artistic side of medicine shaped her education to become a hematologist.

Research

Blocking the progression of pre-leukemic disorders

Erin Podolak, MA

Genetic changes in the biology of blood cells can lead them down a path to cancer. This researcher is figuring out how that happens.

Profiles

Experiences as a volunteer shaped Crabtree’s professional career

St. Jude Progress

St. Jude highlights Valerie Crabtree who offers insights and tips for those interested in pursuing a psychology career.

Outreach

COVID-19 vaccine FAQ: Infectious disease and virus experts weigh in

Diego R. Hijano, MD, MSc

Just how effective are COVID vaccines? Should you get one? A virologist and an infectious diseases physician have answers to those questions and more.

Global Health

Launching CureAll: the road for countries to improve global pediatric cancer care, save a million lives and reduce suffering for all

Catherine G. Lam, MD, MPH

Read how St. Jude and the World Health Organization are partnering to save a million lives and reduce suffering for all.

Profiles

Miller’s approach to science shaped by practical creativity and a curious spirit

Chris Pennington

Shondra Miller, PhD, director of the Center for Advanced Genome Engineering, credits her parents for instilling a love of science.