Research

Learn about published research as well as leading-edge basic and translational research initiatives from St. Jude laboratories.

illustration of a brain tumor
illustration of a brain tumor

Understanding the clinical outcomes of a rare but distinct low-grade glioma

Brian O'Flynn, PhD

Putting patients first offers holistic view of disease

graphic representation of math in medicine
graphic representation of math in medicine

Math behind the medicine

Brian O'Flynn, PhD and Jessie Newman

Explore how mathematics influences all that we do at St. Jude

A woman and man looking at a computer screen that shows an image of cells
A woman and man looking at a computer screen that shows an image of cells

The long and the short of the cell antenna

Brian O'Flynn, PhD

Explore the pathway linking Sonic Hedgehog signaling with cilium length

two men talking one is holding a report
two men talking one is holding a report

Exploring biomolecular condensate networks’ internal structure

Brian O'Flynn, PhD

See how molecular dynamics revealed the inhomogeneous nature of biomolecular condensates

Four women talk in front of screen
Four women talk in front of screen

Distinct molecular profiles lead to a better understanding of acute leukemia

Emilia Asante, PhD

Distinct molecular profiles in acute myeloid leukemia (AML) and T-cell acute lymphoblastic leukemia/lymphoma (T-ALL/LLy) with PICALM::MLLT10 (PM) fusions shed light on potential targeted therapies for improved outcomes.

A glimpse beyond life and death: Exploring the biology of the MICOS complex

Brian O'Flynn, PhD

See how new model offers glimpse into vital mitochondrial complex

Influenza virus provides first evidence of bats’ potential as an intermediate host

Alex Generous, PhD

Explore research showing bats may be an intermediate influenza host.

Blazing a TRAIL in acute myeloid leukemia treatment

Brian O'Flynn, PhD

See how studies into AML drug reveals new potential target

Study reveals the neurochemical gatekeeper to learning and the key to unlocking it

Brian O'Flynn, PhD

St. Jude research uncovers neural secrets behind our capacity to learn

Drug which blocks stress granule formation offers insight into biomolecular condensates

Brian O'Flynn, PhD

See how G3BP inhibitors represent turning point in RNP granule research