Research News & Publications

Control of rhabdomyosarcoma cell identity provides clues to possible treatments

09/17/2021

Findings from St. Jude Children’s Research Hospital show how control of transcription factors by a common tumor suppressor gene may provide a therapeutic opportunity in a type of childhood cancer.
Research reveals new treatment strategy for propionic acidemia

09/15/2021

Findings from St. Jude Children’s Research Hospital shed light on what drives this metabolic disease and provides clues to targeted treatment with pantazines.
Research provides evidence for how a key transcription factor manages access to DNA

09/07/2021

St. Jude scientists have revealed a previously unknown role for CTCF, a pivotal transcription regulator linked to cancer.
The PANoptosome: a new frontier in innate immune responses

09/01/2021

St. Jude scientists detail how inflammasomes act as integral components of mega-cell death complexes called PANoptosomes for host defense in live viral and bacterial infections.
Meet the PANoptosome

09/01/2021

St. Jude scientists found that inflammasomes can work with other cell death pathway molecules, resulting in a mega-cell death complex called a PANoptosome.
St. Jude and leading cancer centers urge vaccination to protect against HPV and other diseases

08/30/2021

NCI-designated cancer centers, AACI members and other cancer centers and medical groups endorse HPV vaccination and cancer screening to eliminate cancers caused by the virus.
Research tool builds neighborhoods of data

08/23/2021

St. Jude scientists created a tool to compare T-cell receptor sequence and gene-expression data.
Bringing protein structures in from the cold

08/18/2021

Findings from St. Jude show that protein structures obtained from cryogenic (frozen) techniques can lead to incorrect or missing information and throw off computational models.
Retinoblastoma resource: Researchers create more accurate research model

08/05/2021

St. Jude Children’s Research Hospital scientists have created a model of the rare pediatric eye cancer that more closely mimics the biology of patient tumors.
New insight into red blood cell machinery offers clues to treating sickle cell disease

08/02/2021

Scientists at St. Jude have uncovered how the body generates protective fetal hemoglobin against sickle cell disease and beta thalassemia.