Method for improving seasonal flu vaccines also aids pandemic prediction
Influenza (flu) vaccines and pandemic predictions can be improved; learn how St. Jude scientists found impactful hemagglutinin mutations contributing to both.
Integrated structural biology provides new clues for cystic fibrosis treatment
Learn about how the cystic fibrosis transmembrane conductance regulator works and how findings from St. Jude will help therapeutic development.
Kevin Krull, Ph.D., promoted to chair of the Department of Psychology and Biobehavioral Sciences
The renamed department will investigate the biological mechanisms underlying the effects of catastrophic disease on the brain.
St. Jude approach prevents drug resistance and toxicity
Explore how St. Jude scientists overcame drug resistance and drug toxicity, using X-ray crystallography to avoid the detoxification pregnane X receptor (PXR).
Octavio Ramilo, M.D., named chair of the Department of Infectious Diseases at St. Jude Children’s Research Hospital
Internationally renowned expert will focus on growing St. Jude into a global leader in infectious diseases research.
A molecular ticket to ride: St. Jude scientists capture the cellular train that enables transport in cilia
Find out how Scientists at St. Jude solved the 3D structure of a cellular train in cilia, IFT-A, at nearly ten times the resolution of previous efforts.
Access matters: lack of resources is associated with increased mortality in childhood cancer survivors
Find how increased mortality in childhood cancer survivors is independently associated with local resource deprivation and certain chronic health conditions.
Detect minor clones in blood cells: St. Jude looks deep to find source of accelerated aging in childhood cancer survivors
Explore how deep sequencing childhood cancer survivors found the mutational fingerprint of a toxic chemotherapy associated with a marker of accelerated aging.
Protein ‘anchor’ gives immunotherapy a boost
Relapsed cancer is challenging to treat. St. Jude scientists are studying how to use a chimeric antigen receptor (CAR) to target cancer cells, an approach that attracts immune cells that can destroy cancer.
St. Jude scientists create more efficient CAR immunotherapies using a molecular anchor
Discover how chimeric antigen receptors (CARs) with a new anchor domain increased anti-cancer activity of cellular immunotherapies in cancer models.
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