Relapsed cancer is challenging to treat. St. Jude scientists are studying how to use a chimeric antigen receptor (CAR) to target cancer cells, an approach that attracts immune cells that can destroy cancer.
Discover how chimeric antigen receptors (CARs) with a new anchor domain increased anti-cancer activity of cellular immunotherapies in cancer models.
Immunologist recognized for her achievements in innate immunity, developing new concepts in inflammasome biology, inflammatory cell death.
Julie R. Park, M.D., to succeed longtime chair Ching-Hon Pui, M.D.
Scientists at St. Jude used an innovative degradation system on CTCF, learning more about this protein’s role in transcription. Read about the findings.
St. Jude scientists have captured the 3D structure of the SPOP protein, revealing how it contributes to cancer. Read about the implications for therapeutics.
St. Jude scientists performed the largest study yet examining drug sensitivity in childhood acute lymphoblastic leukemia across genomic subtypes and its association with treatment response.
Named as Memphis Business Journal’s 2022 Class of 40 Under 40, Spicer Robertson’s motto is ‘Live in your vision, not your circumstances.’ Read how this native Memphian and founder of the DEI Collective has made her way back to the Mid-South as the chief diversity, equity and inclusion officer of St. Jude Children’s Research Hospital.
Dr. Plummer leads new program at St. Jude, exploring novel ways of measuring gene expression while preserving cellular organization.
By simulating molecular dynamics, St. Jude scientists revealed how the selectivity or promiscuity of GPCR coupling relies on the location and duration of intermolecular interactions.
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