Findings from St. Jude Children’s Research Hospital show how control of transcription factors by a common tumor suppressor gene may provide a therapeutic opportunity in a type of childhood cancer.
Findings from St. Jude Children’s Research Hospital shed light on what drives this metabolic disease and provides clues to targeted treatment with pantazines.
St. Jude scientists have revealed a previously unknown role for CTCF, a pivotal transcription regulator linked to cancer.
St. Jude scientists detail how inflammasomes act as integral components of mega-cell death complexes called PANoptosomes for host defense in live viral and bacterial infections.
St. Jude scientists found that inflammasomes can work with other cell death pathway molecules, resulting in a mega-cell death complex called a PANoptosome.
NCI-designated cancer centers, AACI members and other cancer centers and medical groups endorse HPV vaccination and cancer screening to eliminate cancers caused by the virus.
St. Jude scientists created a tool to compare T-cell receptor sequence and gene-expression data.
Findings from St. Jude show that protein structures obtained from cryogenic (frozen) techniques can lead to incorrect or missing information and throw off computational models.
St. Jude Children’s Research Hospital scientists have created a model of the rare pediatric eye cancer that more closely mimics the biology of patient tumors.
Scientists at St. Jude have uncovered how the body generates protective fetal hemoglobin against sickle cell disease and beta thalassemia.
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