Research News & Publications

Protein ‘anchor’ gives immunotherapy a boost

02/02/2023

Relapsed cancer is challenging to treat. St. Jude scientists are studying how to use a chimeric antigen receptor (CAR) to target cancer cells, an approach that attracts immune cells that can destroy cancer.
St. Jude scientists create more efficient CAR immunotherapies using a molecular anchor

02/02/2023

Discover how chimeric antigen receptors (CARs) with a new anchor domain increased anti-cancer activity of cellular immunotherapies in cancer models.
Thirumala-Devi Kanneganti, Ph.D. named 2022 AAAS Fellow

01/31/2023

Immunologist recognized for her achievements in innate immunity, developing new concepts in inflammasome biology, inflammatory cell death.
St. Jude names leading researcher as new chair of oncology department

01/26/2023

Julie R. Park, M.D., to succeed longtime chair Ching-Hon Pui, M.D.
Pioneering approach advances study of CTCF protein in transcription biology

01/25/2023

Scientists at St. Jude used an innovative degradation system on CTCF, learning more about this protein’s role in transcription. Read about the findings.
Structural insights reveal how SPOP protein contributes to cancer

01/23/2023

St. Jude scientists have captured the 3D structure of the SPOP protein, revealing how it contributes to cancer. Read about the implications for therapeutics.
Pharmacotyping of childhood leukemia provides a blueprint for ‘true precision medicine’

01/05/2023

St. Jude scientists performed the largest study yet examining drug sensitivity in childhood acute lymphoblastic leukemia across genomic subtypes and its association with treatment response.
St. Jude names Lori Spicer Robertson chief diversity, equity and inclusion officer

12/13/2022

Named as Memphis Business Journal’s 2022 Class of 40 Under 40, Spicer Robertson’s motto is ‘Live in your vision, not your circumstances.’ Read how this native Memphian and founder of the DEI Collective has made her way back to the Mid-South as the chief diversity, equity and inclusion officer of St. Jude Children’s Research Hospital.
St. Jude names Jasmine Plummer, Ph.D., as director of Center for Spatial Omics

12/06/2022

Dr. Plummer leads new program at St. Jude, exploring novel ways of measuring gene expression while preserving cellular organization.
Space and time influence G-protein coupled receptor interactions

12/05/2022

By simulating molecular dynamics, St. Jude scientists revealed how the selectivity or promiscuity of GPCR coupling relies on the location and duration of intermolecular interactions.