St. Jude Research
Chair: Stephen Gottschalk, MD

Department of Bone Marrow Transplantation & Cellular Therapy  

  

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Mission and vision

The mission of the Department of Bone Marrow Transplantation and Cellular Therapy at St. Jude is to advance cures for pediatric catastrophic diseases through research and treatment focused on cell, gene and immune therapies.

Our vision is to cure pediatric catastrophic diseases with minimal treatment-related harm.

About the department

The St. Jude Department of Bone Marrow Transplantation & Cellular Therapy Program treats newborns, infants, children, adolescents and young adults who have a malignant or nonmalignant life-threatening disorder that is treatable with i) autologous or allogeneic a hematopoietic cell transplantation (HCT), ii) gene-editing and gene therapy, stem cell/bone marrow transplant with autologous cells or allogeneic cells, or iii) adoptive cell therapy.

Children with life-threatening illnesses who are undergoing hematopoietic stem cell/bone marrow transplant require highly specialized resources and experienced faculty and staff, such as those available at St. Jude, to meet their medical, physical, psychological, social and developmental needs. Our transplant and cellular therapy program is accredited by the Foundation for Accreditation of Cellular Therapy (FACT), and the Center for International Blood and Marrow Transplant Research (CIBMTR).

Our laboratory and clinical research interests are focused on haplo-identical HCT, graft engineering, approaches to enhance immune reconstitution post HCT, cell therapy with genetically modified immune cells — including chimeric antigen receptor (CAR) T cells — and gene-editing and gene therapy for non-malignant diseases.

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Many of our laboratory and clinical research studies are conducted in close collaboration with the Departments of Oncology, Hematology, Immunology, Surgery, and Infectious Diseases, the Center of Excellence for Pediatric Immuno-Oncology, the Human Applications Laboratory and St. Jude GMP facility. We also participate in studies from the Children's Oncology Group (COG), the National Marrow Donor Program (NMDP), and the Pediatric Transplantation & Cellular Therapy Consortium (PTCTC).

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St. Jude investigators have the freedom to focus on making big discoveries, backed by extraordinary resources and support teams. We are always looking for highly motivated scientists and engineers with passion and talent to join us!

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We are currently recruiting!

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Contact us

Department of Bone Marrow Transplantation & Cellular Therapy
Amy Prior, Administrative Director
MS 321, Room I4112
St. Jude Children's Research Hospital

262 Danny Thomas Place
Memphis, TN, 38105-3678 USA
901-595-2554 amy.prior@stjude.org
262 Danny Thomas Place
Memphis, TN, 38105-3678 USA
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