Discovery of a metabolic pathways that inhibit memory T cell production has potential for enhancing the immune system’s ability to fight infections and cancers.
St. Jude has discovered a mechanism that tumors use to switch on protective regulatory T cells, raising the potential for drug treatments that render tumors more vulnerable to cancer immunotherapy.
The project will expand and enhance data collection in low- and middle-income countries to support the global push to advance childhood cancer survival.
Research from scientists at St. Jude Children’s Research Hospital found mutations up to two years before cancer developed, showing an opportunity for early interventions.
St. Jude scientists are studying mutations that lead to a certain kind of treatment-related blood cancer.
New Zealand’s experience during the first wave of COVID-19 suggests nonpharmaceutical interventions should be considered to control severe viral respiratory outbreaks in the future.
St. Jude Children’s Research Hospital scientists have created a CAR-T cell receptor designed to improve the effectiveness of immunotherapy for treatment of solid tumors.
St. Jude scientists are studying the molecular mechanisms responsible for medulloblastoma treatment failure and recurrence.
St. Jude scientists created a free mathematical tool to find instrument-caused errors.
Multidisciplinary research identifies novel targeted therapy for children with acute lymphoblastic leukemia
Scientists at St. Jude have revealed a potential treatment for T Cell ALL using a method that has implications for how cancer therapies are identified in the future.
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