2021 Archive

Research

Integrated sequencing approach delivers the most reliable pediatric AML diagnosis

Brian O'Flynn, PhD

See how combining sequencing approaches provides a ‘one-stop shop’ for diagnosing AML.

Pharmaceutical Sciences

Finding the balance between efficacy and toxicity in pediatric cancer treatment

Alex Generous, PhD

Discover how researchers find ways to improve treatments with genetic information.

Outreach

St. Jude affirms commitment to global childhood health at United Nations General Assembly

Lance Wiedower

The work of St. Jude Global was on display at the 80th session of the United Nations General Assembly.

Pharmaceutical Sciences

The circuitous path from chemical compound to clinical trial

Heather Johnson

St. Jude scientists are making progress in the treatment of pediatric cancer by translating new drug findings from the lab to the clinic.

Profiles

5 Questions for Andrew Kleist, MD, PhD

Andrew Kleist, MD, PhD and Alex Generous, PhD

Meet Andew Kleist, MD, PhD, a 2025 STAT Wunderkind early career scientist.

Research

Genomic Medicine Initiative (GEMINI) targets unmet needs in rare disease treatment

Jake Hopkins, MBA and Brian O'Flynn, PhD

Learn how GEMINI addresses the challenges of rare genetic diseases

Profiles

Navigating a non-traditional path to becoming a scientist

Matthew Fisher

Meet graduate student Matthew Fisher to learn about his atypical scientific career progression.

Survivorship

St. Jude calculators crunch the numbers to empower survivors of childhood cancer

Alex Generous, PhD

Find about these free resources, which scientists keep current with the most current survivorship research.

Profiles

Finding my path from baseball to biomedical science

Jordan Bondrowski

A chance encounter at a baseball game as a child set Jordan Bondrowski on the path toward becoming a student in the St. Jude Graduate School of Biomedical Sciences.

Research

Demystifying a methylation mystery at the fetal hemoglobin gene promoter

Alex Generous, PhD

Learn how St. Jude scientists answered a decades-old mystery with implications for sickle cell anemia and beta thalassemia treatment.

Research

For the growing number of childhood cancer survivors, five-year survival is just the beginning

AnnaLynn Williams, PhD

As cancer survivorship changes, new benchmarks must be set to redefine survivorship research and treatment success.

Outreach

Advocating globally for a COVID-19 vaccine

Miguela Caniza, MD, MPH

It’s essential to provide an accurate, science-based website for vaccine information. The St. Jude Global COVID-19 Working Group plans to provide accurate COVID-19 information, including answering questions and providing vaccine news as it emerges.

Outreach

We can – we will – accelerate progress globally

James R. Downing, MD

St. Jude Children’s Research Hospital is launching the largest strategic investment in its nearly 60-year history, committing $11.5 billion during the next six years to accelerate research and treatment globally for children with catastrophic diseases.

Research

The heart of the matter – cancer survivors and heart disease

Matthew J. Ehrhardt, MD

Cancer treatments can result in damage to the heart both during treatment and years following completion of therapy. As many cancer survivors are now living longer into adulthood, we’re gaining a better understanding of some of the late effects of cancer treatments that we weren’t able to observe before.

Research

Immune markers offer clues to antibody production in response to flu

Mary Powers

Scientists are learning more about antibody production in response to flu, including how they develop from helper T cells and monocytes.

Clinical

Cancer care during a pandemic: What we learned prepares us for the next emergency

Dylan Graetz, MD, MPH

The pandemic exposed shortcomings in health care. But this study revealed more than expected in this type of children’s treatment.

Outreach

Learning the value of mentors, champions and building a strong network

St. Jude Progress

Tangie Thomas, MPH, is vice president of Clinical Trials Operations at St. Jude Children’s Research Hospital.

Investigator Insights

Jasmine Turner: Overcoming obstacles, rising to meet challenges

Mike O’Kelly

For Jasmine Turner, resilience and tenacity were required to enter a field with very few Black women. There weren’t many women or teachers of color in her scientific courses—no one with similar experiences to help guide her or focus her talents. She turned to her mother for encouragement and inspiration.

Clinical

What we’ve found out about hearing loss and cognitive function in children

Johnnie Bass, AuD, PhD

This study, to our knowledge, is the first to objectively measure hearing and neurocognitive function in a large cohort of long-term survivors of childhood cancer stratified by treatment exposures.

Investigator Insights

Making purposeful connections to help others grow and develop

Chris Pennington

Andrea Stubbs shares her experiences that shaped her career in community outreach to raise awareness for both HIV and HPV.