Research Highlights - Promise Spring 2017 Discoveries and Achievements Second cancer risk declines in survivors of childhood cancer Changes in childhood cancer treatment, including the reduced use of radiation therapy, has reduced the risk for second cancer in survivors. Les Robison, PhD, receives national award The hospital's Epidemiology and Cancer Control Chair, Les Robinson, PhD, is awarded the ACS Medal of Honor. Biostatisticians build a better analytic tool Researchers craft a new approach for mining genomic data for rare genetic variations that may play a role in disease risk. Loss of ARID1A protein drives colon cancer Research reveals principal tumor suppressor function of ARID1A and suggests that loss of the protein contributes to colon cancer Why do some leukemia patients relapse? Research suggests ancestry plays a role in why some cancer returns. Mystery molecule is a key to thwarting colon cancer Mystery sensor protein NLRC3 revealed as a central player in preventing colon cells from becoming cancerous Research provides insights into adolescents’ care-planning needs Adolescents as young as 14 want to be part of the conversation about end-of-life care, and families indicate they want to hear from their children. Discovery linked to two neurological diseases New findings help increase understanding of molecular mechanisms for common forms of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). From Promise, Spring 2017 Donate Now Subscribe to Promise Name: Email: Message: Submit Feedback Thank you for your feedback! More articles from this issue Childhood Leukemia: High Risk, High Rewards In St. Jude labs and clinics, scientists work day and night to find cures for children with high-risk leukemias. Blood and Platelets: A Different Kind of Donation St. Jude performs about 800 blood product transfusions each month. You can help a child by donating blood or platelets in Memphis. Bringing Science into the Classroom Through St. Jude cancer education activities, research comes alive for students and their teachers. Saving Eyes and Lives Worldwide St. Jude harnesses technology to aid in the early detection and diagnosis of the eye cancer retinoblastoma. Saving Kids in Your Community The St. Jude Give thanks. Give hope. campaign helps support St. Jude, whose treatment plans can save lives in hometowns like yours. The Early Childhood Clinic: A Second Chance at a First Start The St. Jude Early Childhood Clinic helps babies and toddlers achieve developmental milestones during treatment. Scientific Sleuths Solve Medical Mystery St. Jude scientists investigate a genetic mutation that rendered a bacteria antibiotic-tolerant. In finding the cure, they may save more lives. Helping the Children A couple uses a donor-advised fund to help St. Jude kids. Survivor Tim Wigginton Is On Top of the World This cancer survivor acquired tenacity and drive through his journey with non-Hodgkin lymphoma. Out of this World St. Jude patients join BestBuy employees in creating crafts, playing with mini robots and mixing tunes.