News and Highlights - Summer 2019 Roussel elected to National Academy of Sciences Roussel’s appointment marks a historic moment in National Academy of Sciences history with a record number of women elected to the academy. Researchers reveal key process that regulates cell division Read how fluctuations in the intrinsically disordered protein p27 play a key role in regulating cell division. Schedule changes improve ALL treatment Scheduling delivery of the drug asparaginase with a discontinuous schedule of dexamethasone helps reduce bone damage when the two drugs were given together. How do we get more out of vaccine protection? Cell Host & Microbe study reveals the nearly 70 proteins the bacteria need to spread and set up shop (colonize) on someone new. First St. Jude director and CEO honored as Giant of Cancer Care The Giants of Cancer Care recognition program honors those who advance the field of oncology through research or clinical care. Different immune cell implicated in lupus-related kidney disease This work shows for the first time that a type of immune cell called a patrolling monocyte plays a critical role in glomerulonephritis, inflammation of the kidneys St. Jude physician-scientist receives AACR award The 2019 Gertrude B. Elion Cancer Research Award supports researchers to advance research focused on the cause, diagnosis, treatment or prevention of cancer. Biological machinery of cell’s “executioner” yields secrets of its control Discovery of control signals for cell-killing necroptosis promises new treatment pathway for cancers and a broad array of other disorders. Mechanism revealed that dooms patients with Lou Gehrig disease Read about how the most common genetic cause of ALS disrupts cell function and how that might lead to new ways to diagnose and treat the disease Tracking the source of bone cancer mutations Read about efforts to improve cure rates for the bone cancer osteosarcoma by tracking how the chemo drug cisplatin may contribute to mutations. Genetic secrets yield treatment clues Genomic analysis reveals age-related subsets of acute erythroid leukemia. Flu and strep team up to cause respiratory woes Researchers report for the first time that flu sticks to the surface of common respiratory bacteria. Summer 2019 Table of Contents Subscribe to Promise Full Name Email* Submit Share through Facebook Twitter LinkedIn E-Mail Share Close From Promise, Summer 2019 Donate Now Subscribe to Promise Name: Email: Message: Submit Feedback Thank you for your feedback! More articles from this issue Reading Skills: Windows to the World By pinpointing cognitive skills necessary for reading, scientists work to improve quality of life for hearing-impaired brain tumor survivors. One Million Dollars: Mission Possible In an effort to give back to the hospital that saved his life, a St. Jude patient raises an army of fundraisers working toward a single goal. When It Comes to Quality, Safety Matters St. Jude sets the standard for quality, patient care and clinical improvement science for children with life-threatening diseases. Integrative Medicine: Body, Mind and Spirit An integrative medicine program offers a new level of holistic care to St. Jude patients. New HIV Cases: Operation Zero St. Jude sets a goal of having zero new HIV cases in Memphis by 2030. DIPG: Focused Steps St. Jude clinical trial tests chemotherapy that crosses the blood-brain barrier to reach a deadly brain tumor. Generosity Makes an Impact After researching St. Jude, one businessman supports the hospital’s work to find cures, save children and share knowledge worldwide. Radiation and Ependymoma: The Sweet Taste of Success With more than a decade of follow-up, results from a newly published clinical trial show that radiation after surgery triples survival for kids with ependymoma. Melanoma Mutation: Hide and Seek St. Jude researchers find a new melanoma mutation in kids and adults. Life after St. Jude: A Positive Outlook How St. Jude helped me take control of my health and set a course for helping others. Glamour and Glitz St. Jude Child Life hosts Teen Formal and other events to provide patients with a sense of normalcy during treatment.