Research reveals structural details of chaperones, critical molecules of the cell St. Jude scientists have uncovered a new discovery that reveals how chaperones manage protein folding – which could lead to finding ways to fight disease. St. Jude will help lead national push to create more effective flu vaccines Flu is particularly dangerous for some people, including young cancer patients. Here’s the latest on how St. Jude scientists are working to protect them. Do vitamins A and D help the flu vaccine work better? It depends. Vitamins A and D can impact how well some children respond to the flu vaccine. Exercise may give the brain a boost A St. Jude study reveals more about the link between cancer survivors’ physical fitness and their thinking and learning skills. Clinical trial lowers ALL relapse rate Results are in from a ten-year long clinical trial aimed at preventing relapse in pediatric patients with acute lymphoblastic leukemia. Step aside Marie Kondo, the genome is the real organizational expert St. Jude researchers have uncovered the secrets of genome packaging revealed in the 3D genome. Reimagining β-thalassemia and its treatment Read the latest on a possible role for rapamycin treatment for b-thalassemia. Taking a wider view reveals potential targets for rhabdoid tumors New study finds new rhabdoid tumor targets by identifying which targets these tumors need to survive. Molecule offers focus for taming inflammation Chronic inflammation can be deadly. St. Jude researchers have identified a molecule that might lead to new ways to shut it down. From Promise, Winter 2020 Donate Now Subscribe to Promise First name: Last name: Email: Message: Submit Feedback Thank you for your feedback! More articles from this issue Paws at Play: A Message from Puggle Therapy dogs in the St. Jude Paws at Play program make the day a little easier for patients—whether helping them relax during procedures, demonstrating how to take medicine or climbing on a mock scanner to show them MRIs aren’t scary. An Added Boost for Medulloblastoma: SJELIOT SJELIOT, a St. Jude-led clinical trial for medulloblastoma, tests prexasertib, a drug that enhances the power of other chemotherapies. Scientists Collaborate to Create a Lattice Light-Sheet Microscope To build a next-generation lattice light-sheet microscope, St. Jude neurobiologists work with a Nobel laureate and a select team of scientists. Cancer Survivors Build Bridge to a Healthy Future St. Jude helps childhood cancer survivors take control of their health by building lifelong relationships with their primary care providers. Minds Over Matter: St. Jude Research Collaboratives The St. Jude Research Collaboratives unite global experts from many different institutions to answer outstanding scientific questions. Soft Landings with the Transition Oncology Program The new Transition Oncology Program (TOP) provides support and education to families whose children are returning home after cancer therapy. LANDO Discovery Has Implications for Cancer Immunotherapy and Alzheimer’s Disease Activating LANDO, or LC3-associated endocytosis, appears to offer protection against neurodegenerative disease and guard against toxic neuroinflammation and neurodegeneration, including memory problems. Sharing Data Worldwide St. Jude is helping drive a new age of information-sharing, providing a roadmap for investigators complete with data, tools and resources. By using sophisticated technology, St. Jude shares this data with the global community. Life after St. Jude: We are the Champions Everyone wins when childhood cancer survivors volunteer to help tomorrow’s patients through St. Jude LIFE, the hospital’s long-term follow-up study. R is for Robot: Automating Drug Screening Scientists in the High-Throughput Bioscience Center use robots to automate the screening of hundreds of thousands of compounds to discover potential new drugs.