Research

Learn about published research as well as leading-edge basic and translational research initiatives from St. Jude laboratories.

Ramilo brings RSV expertise to St. Jude

Alex Generous, PhD

Discover Ramilo's plans for St. Jude RSV research.

Metastatic cancer cells thrive in harsh microenvironments

Erin Podolak, MA

Like a journey through space, metastatic cells have to adapt to spread throughout the body.

Data-driven science helps researchers design new protein interactions

Erin Podolak, MA

With a comprehensive approach to thinking about data, St. Jude scientists are fueling progress.

Biostatisticians are key to getting therapies to patients faster

Xiaomeng Yuan, PhD and Haitao Pan, PhD

Platform Design, a software package, enables clinicians to add study arms to a clinical trial.

Global palliative care requires on-the-ground understanding

Michael J. McNeil, MD

The ADAPT study revealed barriers that stand in the way of palliative care in Latin America.

Liver toxicity and ALL: Genomics drive variability between patients

Erin Podolak, MA

Research reveals how inherited genetic variants can contribute to liver toxicity after chemotherapy.

Math test points metastatic breast cancer treatment in the right direction

Alex Generous, PhD

St. Jude computational biologists created a computational score predicting cancer drug sensitivity to HDAC6 inhibitors in a promising phase Ib clinical trial.

On the road to resistance: How bacteria can win the game of life ‘with a little help from their friends’

Erin Podolak, MA

St. Jude scientists have learned that bacteria are more successful at developing antibiotic resistance when they swap genes through recombination.

New model mimics progression of pediatric bone marrow failure

Alex Generous, PhD

St. Jude scientists have created the first model that faithfully recapitulates details of pediatric bone marrow failure.

CDK6: A well-known kinase commits a new ‘crime’ connecting outer radial glia to microcephaly

Erin Podolak, MA

Microcephaly is a rare neurodevelopmental condition in which a baby’s head is much smaller than expected because the brain did not develop properly or stopped developing during pregnancy. St. Jude researchers identified cells in the outer radial glia in the developing brain that play an important role in microcephaly.