St. Jude Research

Research

Learn about published research as well as leading-edge basic and translational research initiatives from St. Jude laboratories.

Staff scientists in core research facilities accelerate and broaden biomedical discovery
Staff scientists in core research facilities accelerate and broaden biomedical discovery

Staff scientists in core research facilities accelerate and broaden biomedical discovery

 Gary Bridgman

These labs are highly specialized and deliver researchers access to advanced and speedy scientific results.

CHANGE-seq: a novel, simple and scalable method to understand genome editors
CHANGE-seq: a novel, simple and scalable method to understand genome editors

CHANGE-seq: a novel, simple and scalable method to understand genome editors

 Shengdar Tsai, PhD

Making DNA into a circle, called molecular circularization, has revealed a whole new way to look at genome editing.

Searching for the next pandemic flu virus? There’s another factor to keep in mind.
Searching for the next pandemic flu virus? There’s another factor to keep in mind.

Searching for the next pandemic flu virus? There’s another factor to keep in mind.

 Mary Powers

Researchers find the stability of this protein is key to the pandemic potential of swine flu.

Searching for answers to rare cancers in the TP53 gene
Searching for answers to rare cancers in the TP53 gene

TP53: One important gene in rare cancers - an update

 Emilia Modolo Pinto, PhD

St. Jude clinicians and researchers seek answers to some of the rarest pediatric tumors and diseases, including adrenocortical tumors. Read more about their work uncovering the TP53 gene.

Cloud redesign offers enhanced user experience
Cloud redesign offers enhanced user experience

Cloud redesign offers enhanced user experience

 Clay McLeod

Read how this redesign offers computational scientists an edge when it comes to genomics and other omics.

Collaborating on SARS-CoV-2 and pediatric cancer
Collaborating on SARS-CoV-2 and pediatric cancer

Collaborating on SARS-CoV-2 and pediatric cancer

 Miguela Caniza, MD, MPH

This collaboration on infection prevention pivoted early in the SARS-CoV-2 pandemic and did this global pediatric cancer community.

A vaccine to prevent ear infections? Here’s the latest
A vaccine to prevent ear infections? Here’s the latest

A vaccine to prevent ear infections? Here’s the latest.

 Mary Powers

Almost everyone gets ear infections. This vaccine may change that.

A global resource to learn more about pediatric cancer patients and COVID-19
A global resource to learn more about pediatric cancer patients and COVID-19

A global resource to learn more about pediatric cancer patients and COVID-19

 Nickhill Bhakta, MD, MPH

Little is known about childhood cancer patients who are diagnosed with COVID-19, but a new registry is the first step to finding out.

Researchers take the fight to drug resistance up an octave
Researchers take the fight to drug resistance up an octave

Researchers take the fight to drug resistance up an octave

 Robert J. Autry and William E. Evans, PharmD

Drug resistance is a major reason for treatment failure in children with leukemia, but recent research may have an answer.

Learning more about T cells through studying behavior in Type 1 diabetes
Learning more about T cells through studying behavior in Type 1 diabetes

Learning more about T cells through studying behavior in Type 1 diabetes

 Ben Youngblood, PhD

Learning more about how the body attacks itself in Type 1 diabetes offers insights into how to harness the power of T cells to treat cancer.