Research

Learn about published research as well as leading-edge basic and translational research initiatives from St. Jude laboratories.

(L to R) First author Prahalathan Pichavaram, PhD, corresponding author Andrew Murphy, MD, St. Jude Department of Surgery and co-author Carolyn Jablonowski, PhD.

(L to R) First author Prahalathan Pichavaram, PhD, corresponding author Andrew Murphy, MD, St. Jude Department of Surgery and co-author Carolyn Jablonowski, PhD.

Ribosome production presents a new therapeutic opportunity against Wilms tumor

Alex Generous, PhD

Discover how disruption ribosomes creation provides promise for “undruggable” cancers.

Ashraf Mohommed and Aseem Ansari

Ashraf Mohommed and Aseem Ansari

Just like the real thing: Synthetic gene expression regulators demonstrate success

Brian O'Flynn, PhD

See how Aseem Ansari's SynGRs target BET proteins, offering potential for treating diseases like Friedreich’s ataxia and advancing BET domain understanding

Clifford Brangwynne, PhD, Princeton University

Clifford Brangwynne, PhD, Princeton University

St. Jude Research Collaboratives program reaches across institutional boundaries to multiply impact

Jessica Gullett-Rubino, PhD

Learn more about how the St. Jude Research Collaboratives Program is driving scientific breakthroughs.

Leukemia and Down Syndrome illustration

Leukemia and Down Syndrome illustration

Consortium on leukemia in children with Down syndrome offers energy and optimism

Brian O'Flynn, PhD

Leukemia in children with Down syndrome addressed at St. Jude as international consortium meets

Emily Zheng and Jesse Smith

Emily Zheng and Jesse Smith

Shared Resources Spotlight: Biostatistics Shared Resource

Elizabeth Casolo

Meet the investigators in the Biostatistics Shared Resource to learn how this under-recognized field is a critical component of successful research.

Paul Taylor, et al

Paul Taylor, et al

Preventing neurodevelopmental disorders through genetic compensation

Brian O'Flynn, PhD

See how a gene family is implicated in the cause and rescue of neurodegenerative disease

Nuclear receptor DNA

Nuclear receptor DNA

Electrical engineering sparks discovery in how human nuclear receptors bind to DNA

Brian O'Flynn, PhD

See how nuclear receptors selectively bind to DNA.

Shondra Pruett-Miller, PhD, and Jamaica Siwak at work

Shondra Pruett-Miller, PhD, and Jamaica Siwak at work

Shared Resources Spotlight: Center for Advanced Genome Engineering

Elizabeth Casolo

Research from the Center for Applied Genome Engineering plays a pivotal role in discovery.

Yurika Matsui, PhD, Jamy Peng, PhD, Beisi Xu, PhD,

Yurika Matsui, PhD, Jamy Peng, PhD, Beisi Xu, PhD,

The life and death of cells in early brain development

Brian O'Flynn, PhD

Explore St. Jude research on neural cell life or death during brain development.

Thalassemia illustration

Thalassemia illustration

Missed connection no more: Science and serendipity solve a microRNA mystery

Alex Generous, PhD

Find how a St. Jude discovery holds new promise for beta-thalassemia.

1
2
3
4
5
6
7
8
9
10
11