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The Science of Childhood Cancer

A 15-week virtual lecture series

 
 

The Science of Childhood Cancer lecture series is designed to engage the scientific community on key questions in pediatric cancer research. Invited speakers include leading experts across the spectrum of basic, translational, clinical and population science. Hosted by the St. Jude Comprehensive Cancer Center, the initial 15-week series, which ran from August to November 2020, focused on four themes: Immunotherapy, Chromatin and Transcription in Pediatric Cancer, Novel Approaches to Targeted Molecular Therapies in Pediatric Cancer, and Pediatric Cancer Survivorship.

View lecture recordings below, and sign up for our email list to be notified of future events.

 

Hosts

  • Charles W. M. Roberts, MD, PhD

    Charles W. M. Roberts, MD, PhD

    Roberts

    Member, St. Jude Faculty

    • Executive Vice President
    • Director, Comprehensive Cancer Center
    • Director, Molecular Oncology Division
  • Charles G. Mullighan, MBBS (Hons), MSc, MD

    Charles G. Mullighan, MBBS (Hons), MSc, MD

    Mullighan

    Member, St. Jude Faculty

    • Deputy Director, Comprehensive Cancer Center
    • Co-Leader, Hematological Malignancies Program
    • Medical Director, St. Jude Biorepository
 

Archived Lectures

 
 
 

August 13

 

CAR T Cells: On the Road to Synthetic Immunity

Michel Sadelain, MD, PhD

Director, Center for Cell Engineering
Stephen and Barbara Friedman Chair
Member, Immunology Program
Member, Departments of Medicine and Pediatrics
Memorial Sloan-Kettering Cancer Center

Watch presentation

 
Immunotherapy label
 
 

August 20

 

Chromatin Remodeler Mutations in Cancer: Mechanisms and Therapeutic Vulnerabilities

Charles W.M. Roberts, MD, PhD

Member, St. Jude Faculty
Executive Vice President
Director, Comprehensive Cancer Center
Director, Division of Molecular Oncology
Department of Oncology
St. Jude Children's Research Hospital

Watch presentation

 
Chromatin and Transcription label
 
 

August 27

 

The Future of CAR T Cells for Hematologic Malignancies: Beyond Antigen Targeting

Terry J. Fry, MD

Professor of Pediatrics, Hematology and Immunology
Co-Director, Human Immunology and Immunotherapy Initiative and Director of Cancer Immunotherapy
University of Colorado School of Medicine
Robert and Kathleen Clark Endowed Chair in Pediatric Cancer Therapeutics
Children’s Hospital Colorado, Center for Cancer and Blood Disorders

Watch presentation

 
Immunotherapy label
 
 

September 3

 

Phase Separation in Gene Transcription: From the Nucleolus to Aberrant Transcription in Leukemia

Richard W. Kriwacki, PhD

Co-Leader, Cancer Biology Program
Department of Structural Biology
St. Jude Children's Research Hospital

Watch presentation

 
Chromatin and Transcription label
 
 

September 10

 

Late Effects Among Survivors of Blood or Marrow Transplantation

Smita Bhatia, MD, MPH

Director, Institute for Cancer Outcomes and Survivorship
Gay and Bew White Endowed Chair in Pediatric Oncology
Professor and Vice Chair, Dept. of Pediatrics
School of Medicine, University of Alabama at Birmingham

Watch presentation

 
Survivorship label
 
 

September 17

 

Advancing CAR T Cells for the Treatment of Glioblastoma: Progress and Challenges

Christine Brown, PhD

Heritage Provider Network Professor of Immunotherapy
Deputy Director, T Cell Therapeutics Research Laboratory
City of Hope

Lecture not archived.

 
Immunotherapy label
 
 

September 24

 

Cognitive Outcomes of Childhood Cancer: Neurophysiology, Biomarkers and Interventions

Kevin R. Krull, PhD

Endowed Chair, Cancer Survivorship
Faculty Member, Departments of Epidemiology and Cancer Control, and Psychology
St. Jude Children's Research Hospital

Watch presentation

 
Survivorship label
 
 

October 1

 

3D Chromosomal Organization in Pediatric Leukemia: Impact for Drug Response and Disease Progression

Iannis Aifantis, PhD

Professor and Chair
Department of Pathology and Perlmutter Cancer Center
NYU Grossman School of Medicine

Watch presentation

 
Chromatin and Transcription label
 
 

October 8

 

Medulloblastomics 2020: Biological & Clinical Insights From 1,000s of Patients

Paul A. Northcott, PhD

Associate Faculty Member, Department of Developmental Neurobiology
Division of Brain Tumor Research
St. Jude Children's Research Hospital

Watch presentation

 
Chromatin and Transcription label
 
 

October 15

 

CAR T Cells for Pediatric Cancers: Progress and Challenges

Crystal Mackall, MD

Ernest and Amelia Gallo Family Professor of Pediatrics and Internal Medicine
Founding Director, Stanford Center for Cancer Cell Therapy
Director, Parker Institute for Cancer Immunotherapy at Stanford
Associate Director, Stanford Cancer Institute
Leader, Cancer Immunology and Immunotherapy Program
Director, Cancer Immunotherapy Program
Department of Pediatrics - Hematology & Oncology
Department of Medicine - Blood & Marrow Transplantation
Stanford University

Watch presentation

 
Survivorship label
 
 

October 22

 

Partitioning of Cancer Therapeutics in Nuclear Condensates

Richard A. Young, PhD

Professor, Department of Biology
Member, Whitehead Institute
Massachusetts Institute of Technology (MIT)

Isaac A. Klein, MD, PhD

Dana-Farber Cancer Institute
Whitehead Institute

Watch presentation

 
Targeted Molecular Therapies label
 
 

October 29

 

Harnessing Lineage Plasticity for the Treatment of Neuroblastoma

Rani George, MD, PhD

Associate Professor of Pediatrics, Harvard Medical School
Dept. of Pediatric Hematology/Oncology
Dana-Farber Cancer Institute/Boston Children's Hospital

Watch presentation

 
Targeted Molecular Therapies label
 
 

November 5

 

Organized Destruction and Destructive Organization: The Diversity of Immune Responses Towards Tumors and Pathogens

Paul G. Thomas, PhD

Faculty Member, Department of Immunology
St. Jude Children's Research Hospital

Watch presentation

 
Targeted Molecular Therapies label
 
 

November 12

 

Targeting Neuron-Glial Interactions in Childhood Brain Cancer

Michelle Monje, MD, PhD

Associate Professor, Neurology & Neurological Sciences
Stanford University

Watch presentation

 
Targeted Molecular Therapies label
 
 

November 19

 

Emerging Late Effects of Targeted Molecular Therapies

Eric Chow, MD, MPH

Associate Professor, Clinical Research Division
Associate Professor, Public Health Sciences Division
Director, Prevention Center Shared Resource
Fred Hutchinson Cancer Research Center
Medical Director, Cancer Survivorship Program
Seattle Children's Hospital
Associate Professor, Pediatrics
University of Washington

Watch presentation

 
Survivorship label
 
 

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