The Science of Childhood Cancer lecture series is designed to engage the scientific community on key questions in pediatric cancer research. The initial 15-week series, which ran from August to November 2020, focused on four themes: Immunotherapy, Chromatin and Transcription in Pediatric Cancer, Novel Approaches to Targeted Molecular Therapies in Pediatric Cancer, and Pediatric Cancer Survivorship.
View archived recordings below, or visit our home page to see upcoming live lectures.
August 13
2020
CAR T Cells: On the Road to Synthetic Immunity
Michel Sadelain, MD, PhD
Director, Center for Cell Engineering
Stephen and Barbara Friedman Chair
Member, Immunology Program
Member, Departments of Medicine and Pediatrics
Memorial Sloan-Kettering Cancer Center

August 20
2020
Chromatin Remodeler Mutations in Cancer: Mechanisms and Therapeutic Vulnerabilities
Charles W.M. Roberts, MD, PhD
Member, St. Jude Faculty
Executive Vice President
Director, Comprehensive Cancer Center
Director, Division of Molecular Oncology
Department of Oncology
St. Jude Children's Research Hospital

August 27
2020
The Future of CAR T Cells for Hematologic Malignancies: Beyond Antigen Targeting
Terry J. Fry, MD
Professor of Pediatrics, Hematology and Immunology
Co-Director, Human Immunology and Immunotherapy Initiative and Director of Cancer Immunotherapy
University of Colorado School of Medicine
Robert and Kathleen Clark Endowed Chair in Pediatric Cancer Therapeutics
Children’s Hospital Colorado, Center for Cancer and Blood Disorders

September 3
2020
Phase Separation in Gene Transcription: From the Nucleolus to Aberrant Transcription in Leukemia
Richard W. Kriwacki, PhD
Co-Leader, Cancer Biology Program
Department of Structural Biology
St. Jude Children's Research Hospital

September 10
2020
Late Effects Among Survivors of Blood or Marrow Transplantation
Smita Bhatia, MD, MPH
Director, Institute for Cancer Outcomes and Survivorship
Gay and Bew White Endowed Chair in Pediatric Oncology
Professor and Vice Chair, Dept. of Pediatrics
School of Medicine, University of Alabama at Birmingham

September 17
2020
Advancing CAR T Cells for the Treatment of Glioblastoma: Progress and Challenges
Christine Brown, PhD
Heritage Provider Network Professor of Immunotherapy
Deputy Director, T Cell Therapeutics Research Laboratory
City of Hope
Lecture not archived.

September 24
2020
Cognitive Outcomes of Childhood Cancer: Neurophysiology, Biomarkers and Interventions
Kevin R. Krull, PhD
Endowed Chair, Cancer Survivorship
Faculty Member, Departments of Epidemiology and Cancer Control, and Psychology
St. Jude Children's Research Hospital

October 1
2020
3D Chromosomal Organization in Pediatric Leukemia: Impact for Drug Response and Disease Progression
Iannis Aifantis, PhD
Professor and Chair
Department of Pathology and Perlmutter Cancer Center
NYU Grossman School of Medicine

October 8
2020
Medulloblastomics 2020: Biological & Clinical Insights From 1,000s of Patients
Paul A. Northcott, PhD
Associate Faculty Member, Department of Developmental Neurobiology
Division of Brain Tumor Research
St. Jude Children's Research Hospital

October 15
2020
CAR T Cells for Pediatric Cancers: Progress and Challenges
Crystal Mackall, MD
Ernest and Amelia Gallo Family Professor of Pediatrics and Internal Medicine
Founding Director, Stanford Center for Cancer Cell Therapy
Director, Parker Institute for Cancer Immunotherapy at Stanford
Associate Director, Stanford Cancer Institute
Leader, Cancer Immunology and Immunotherapy Program
Director, Cancer Immunotherapy Program
Department of Pediatrics - Hematology & Oncology
Department of Medicine - Blood & Marrow Transplantation
Stanford University

October 22
2020
Partitioning of Cancer Therapeutics in Nuclear Condensates
Richard A. Young, PhD
Professor, Department of Biology
Member, Whitehead Institute
Massachusetts Institute of Technology (MIT)
Isaac A. Klein, MD, PhD
Dana-Farber Cancer Institute
Whitehead Institute

October 29
2020
Harnessing Lineage Plasticity for the Treatment of Neuroblastoma
Rani George, MD, PhD
Associate Professor of Pediatrics, Harvard Medical School
Dept. of Pediatric Hematology/Oncology
Dana-Farber Cancer Institute/Boston Children's Hospital

November 5
2020
Organized Destruction and Destructive Organization: The Diversity of Immune Responses Towards Tumors and Pathogens
Paul G. Thomas, PhD
Faculty Member, Department of Immunology
St. Jude Children's Research Hospital

November 12
2020
Targeting Neuron-Glial Interactions in Childhood Brain Cancer
Michelle Monje, MD, PhD
Associate Professor, Neurology & Neurological Sciences
Stanford University

November 19
2020
Emerging Late Effects of Targeted Molecular Therapies
Eric Chow, MD, MPH
Associate Professor, Clinical Research Division
Associate Professor, Public Health Sciences Division
Director, Prevention Center Shared Resource
Fred Hutchinson Cancer Research Center
Medical Director, Cancer Survivorship Program
Seattle Children's Hospital
Associate Professor, Pediatrics
University of Washington
