The Science of Childhood Cancer

Lecture Archives

The Science of Childhood Cancer is an interactive, weekly lecture series designed to engage the scientific community on key questions in pediatric cancer research. The series, hosted by the St. Jude Comprehensive Cancer Center, originally launched in August 2020 and features leading experts across the spectrum of basic, translational, clinical and population science. Explore our library of archived lectures below, and visit our registration page to receive updates about upcoming live events.

Prior Lectures: 2020-2024

Date	Speaker	Lecture Title
02.08.2024	Bing Ren, PhD Director, Center for Epigenomics; Professor, Cellular and Molecular Medicine University of California, San Diego	Single-cell epigenome analysis: methods and applications Lecture not archived
02.15.2024	Jian Xu, PhD Member, Center of Excellence for Leukemia Studies, Department of Pathology St. Jude Children’s Research Hospital	Understanding and targeting the non-coding regulatory genome Watch video
02.22.2024	Marcel Kool, PhD Group leader, deputy division head, Division of Pediatric Neuro-oncology, Hopp Children’s Cancer Center (KiTZ) & German Cancer Research Center (DKFZ) Heidelberg, Germany Group leaders, Princess Máxima Center for pediatric oncology, Utrecht, the Netherlands Professor, pediatric brain tumors, University Medical Center Utrecht, Utrecht, the Netherlands	Molecular and clinical analyses of rare pediatric brain tumor types Lecture not archived
02.29.2024	Sharon Castellino, MD, MSc Professor of Pediatrics, Emory University School of Medicine Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta	Beyond owl eyes - advances in pediatric and AYA Hodgkin lymphoma Watch video
03.07.2024	Rising Stars of Cancer Research
	Adam Durbin, MD, PhD Assistant Member, Division of Molecular Oncology, Department of Oncology St. Jude Childrens Research Hospital	Dissecting epigenetic control of transcription in pediatric cancer Watch video
	Jarno Drost, PhD Group leader, Princess Máxima Center for Pediatric Oncology Group leader, Oncode Institute	Organoids in pediatric cancer research Watch video
03.14.2024	Mark Dawson, MBBS (Hons), BMedSci, FRACP, FRCPA, PhD Professor, Sir Peter MacCallum Department of Oncology & Centre for Cancer Research University of Melbourne HHMI International Research Scholar, CCV Sir Edward Dunlop Fellow, Associate Director for Research Translation, Consultant Haematologist (RMH / PMCC) Head, Cancer Biology & Therapeutics Program	Non-genetic mechanisms of clonal dominance in normal and malignant haematopoiesis Watch video
03.21.2024	Kara Davis, DO Stanford University	Understanding treatment resistance and relapse in ALL through single cell studies
03.28.2024	Kai Tan, PhD Professor of Pediatrics, Richard & Sheila Sanford Endowed Chair Children’s Hospital of Philadelphia University of Pennsylvania Perelman School of Medicine	Stem cell programs in high risk leukemias
04.04.2024	Jenny Mack, MD, MPH Associate Professor of Pediatrics Harvard Medical School Associate Chief, Division of Population Sciences, Division of Population Sciences, Faculty Vice President for the Office for Faculty Development, Professionalism, and Inclusion Dana-Farber Cancer Institute	Quality of care for adolescents and young adults with advanced cancer
04.11.2024	Poul Sorensen, BSc, MD, PhD, FRCPC Professor, Department of Pathology & Laboratory Medicine The University of British Columbia	Targeting metabolic vulnerabilities in high-risk childhood cancer using immunotherapy (and other modalities)

Date	Speaker	Lecture Title
08.10.2023	Catherine Bollard, MBChB, MD Children's National Hospital, Children's National Research Institute The George Washington University School of Medicine & Health Services	Cell therapies for pediatric solid tumors – Beyond conventional CAR-T Lecture not archived
08.17.2023	Seth Karol, MD St. Jude Children's Research Hospital Rising Stars of Cancer Research	Novel venetoclax combinations for relapsed pediatric leukemia Watch lecture
08.17.2023	Brian Crompton, MD Dana-Farber Cancer Institute Rising Stars of Cancer Research	Liquid biopsies in pediatric solid tumors: refining treatment and studying tumor evolution Lecture not archived
08.24.2023	Benjamin Greenbaum, PhD Memorial Sloan Kettering Cancer Center Weill Cornell Medicine	Translating the self/nonself discrimination problem in cancer Watch lecture
08.31.2023	Judy Lieberman, MD, PhD Harvard Medical School	Sounding an alarm: Innate immunity makes cancer immunogenic Watch lecture
09.07.2023	David Langenau, PhD Harvard Medical School Mass General Cancer Center	Pushing for new biology and cancer therapies in rhabdomyosarcoma Watch lecture
09.14.2023	Frank Westermann, MD German Cancer Research Center (DKFZ), Heidelberg, Germany	Childhood neuroblastoma: evolution and malignant progression Watch lecture
09.21.2023	Sara Federico, MD St. Jude Children's Research Hospital	Advancing Outcomes for Patients with Neuroblastoma Watch lecture
09.28.2023	Paul Nathan, MD, MSc The Hospital for Sick Children University of Toronto	The financial burden of surviving childhood cancer Watch lecture
10.05.2023	Alejandro Sweet-Cordero, MD University of California-San Francisco	Genomic analysis of osteosarcoma: Making sense of a complex genome to advance translational research and targeted therapy Watch lecture
10.12.2023	Sam Blackman, MD, PhD Day One Biopharmaceuticals	Opportunities and challenges in pediatric oncology drug development: Lessons learned from the biopharmaceutical industry Watch lecture
10.19.2023	Feng Yue, PhD Northwestern University Feinberg School of Medicine	Epigenetic and 3D genome alteration in cancer Lecture not archived
10.26.2023	Annie Huang, MD, PhD, FRCP(C) Hospital for Sick Children University of Toronto	Drivers of transformation in embryonal tumors with multi-layered rosettes (ETMRs) Watch lecture
11.02.2023	Julie Park, MD St. Jude Children's Research Hospital	Neuroblastoma: The power of immunotherapy in pediatric malignancy Watch lecture
11.09.2023	Saro Armenian, DO, MPH City of Hope Comprehensive Cancer Center	Emerging paradigms in cancer survivorship across the lifespan Watch lecture
11.16.2023	Sam Behjati, BMBCh, PhD Wellcome Sanger Institute University of Cambridge, UK	The origins of childhood cancer Watch lecture

Date	Speaker	Lecture Title
02.16.2023	Benjamin Ebert, MD, PhD Harvard Medical School Dana-Farber Cancer Institute	Clonal Hematopoiesis and the Origins of Blood Cancers Watch lecture
02.23.2023	Leontien CM Kremer, MD, PhD Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands	The Dutch Childhood Cancer Survivor Study LATER; Results and Implications Lecture not archived
03.02.2023	Trey Ideker, PhD University of California, San Diego	Building a Mind for Cancer Lecture not archived
03.09.2023	Tara M. Brinkman, PhD St. Jude Children’s Research Hospital	Psychological and Biobehavioral Health Outcomes in Survivors of Childhood Cancer Watch lecture
03.16.2023	Mario Suva, MD, PhD Mass General Hospital Harvard Medical School	Dissecting Adult and Pediatric Gliomas by Single-cell Genomics Lecture not archived
03.23.2023	Giedre Krenciute, PhD St Jude Children’s Research Hospital Rising Stars of Cancer Research	What will it take to make CARTs effective for pediatric brain tumors? Watch lecture
03.23.2023	Maksim Mamonkin, PhD Baylor College of Medicine Rising Stars of Cancer Research	CAR T-cells for T-cell Malignancies: Proving and Improving Watch lecture
03.30.2023	Kathrin M. Bernt, MD The Children's Hospital of Philadelphia University of Pennsylvania	HOX-high Leukemias in Childhood Watch lecture
04.06.2023	Miguel N. Rivera, MD Harvard Medical School Mass General Hospital	Mechanisms of chromatin regulation by EWS fusion proteins Watch lecture
04.13.2023	Asya Agulnik, MD, MPH St. Jude Children's Research Hospital	Harnessing Implementation Science to Improve Outcomes for Children with Cancer who Develop Critical Illness Watch lecture
04.20.2023	Amar Gajjar, MD St. Jude Children's Research Hospital	Evolution of Our Understanding of WNT and SHH Medulloblastoma Watch lecture
04.27.2023	Fernando Camargo, PhD Harvard University	Lineage Histories and Function in the Hematopoietic System Lecture not archived
05.04.2023	Sarah K Tasian, MD Perelman School of Medicine at the University of Pennsylvania Children's Hospital of Philadelphia	Emerging Therapies for Pediatric Leukemia Watch lecture
05.11.2023	Gerald Crabtree, MD Stanford University	Rewiring Cancer Drivers to Activate Apoptosis Watch lecture
05.18.2023	Jeffery M. Klco, MD, PhD St. Jude Children's Research Hospital	New mechanistic insights into the development of pediatric myeloid tumors Watch lecture
05.25.2023	Kim E. Nichols, MD St. Jude Children's Research Hospital	Hereditary Predisposition to Cancer: At the Tip of the Iceberg Watch lecture
06.08.2023	Jinghui Zhang, PhD Clay McLeod Kirsten K. Ness, PT, PhD, FAPTA Xin Zhou, PhD St. Jude Children's Research Hospital	New BIG data resources on St Jude Cloud: The Pediatric Cancer Knowledgebase (PeCanV2) and Survivorship Portal Special Event Watch lecture

Date	Speaker	Lecture Title
08.11.2022	Carl H. June, MD Perelman School of Medicine at the University of Pennsylvania	Engineered T Cells for Cancer Therapy Watch lecture
08.18.2022	Benjamin Youngblood, PhD St Jude Children’s Research Hospital	Identifying Epigenetic Mechanisms of Failure in T Cell-Based Immunotherapy Lecture not archived
08.25.2022	Nada Jabado, MD, PhD McGill University	Oncohistones Organize Chromatin Architecture to Regulate Developmental Programs Watch lecture
09.01.2022	Trever Bivona, MD, PhD University of California, San Francisco	A New Model of Oncogenic Kinase Signaling via Membraneless Cytoplasmic Protein Granules Watch lecture
09.08.2022	John M. Maris, MD Perelman School of Medicine at the University of Pennsylvania	Designing and Developing Pediatric Cancer-Specific Immunotherapies Watch lecture
09.15.2022	David Malkin, MD, FRCPC The Hospital for Sick Children University of Toronto	The Li-Fraumeni Syndrome Genomic Landscape: Harnessing p53 for Clinical Utility Lecture not archived
09.22.2022	Leslie S. Kean, MD, PhD Harvard Medical School Dana-Farber Cancer Institute	From Bedside to Bench and Back to Bedside: Travels in the Systems Biology of GVHD Watch lecture
09.29.2022	Malcolm A. Smith, MD, PhD National Cancer Institute	Pediatric Oncology Drug Development – Learning from Past Successes to Create a Better Future Watch lecture
10.06.2022	Marina Konopleva, MD, PhD University of Texas MD Anderson Cancer Center	Targeting Bcl-2 Family Proteins in Leukemia Watch lecture
10.13.2022	Carlos Rodriguez-Galindo, MD St. Jude Global St. Jude Children's Research Hospital	Curing Childhood Cancer and Curing Children with Cancer – Strategies to Address Global Inequities in Childhood Cancer Care and Control Watch lecture
10.20.2022	Jolanta Grembecka, PhD University of Michigan	Therapeutic Targeting of Epigenetic Modifiers in Leukemia Lecture not archived
10.27.2022	Greg Armstrong, MD, MSCE St. Jude Children's Research Hospital	The Lifetime Impact of Childhood Cancer and Cancer Therapy: The Childhood Cancer Survivor Study Watch lecture
11.03.2022	Dr. Geneviève Almouzni Institut Curie - Research Center / CNRS	Histone Variants and Chaperones in Shaping Chromatin and Cell Fate Lecture not archived
11.10.2022	Robbie Majzner, MD Stanford University Rising Stars of Cancer Research	Co-opting the TCR Machinery to Enhance CAR T Cell Efficacy and Specificity Watch lecture
11.10.2022	Pratiti (Mimi) Bandopadhayay, MBBS, PhD Dana-Farber/Boston Childen's Cancer and Blood Disorders Center Rising Stars of Cancer Research	The Evolution of Pediatric Gliomas Watch lecture
11.17.2022	Sogol Mostoufi-Moab, MD, MSCE Perelman School of Medicine at the University of Pennsylvania	Prognostic Significance of Aberrant Body Composition and Musculoskeletal Deficits in Childhood Cancer Survivors Watch lecture

Date	Speaker	Lecture Title
02.10.2022	Kevin Oeffinger, MD Duke University	Secondary Breast Cancer: A Paradigm for Survivorship Research Watch lecture
02.17.2022	Akiko Shimamura, MD, PhD Harvard Medical School Dana-Farber/Boston Children’s Cancer and Blood Disorders Center	Clonal Evolution and Somatic Reversion in Genetic Predisposition to TP53-Mutated MDS Watch lecture
02.24.2022	Ralph J. DeBerardinis, MD, PhD Children’s Medical Center Research Institute at UT Southwestern	Human Metabolic Outliers Lecture not archived
03.03.2022	Yaël Mossé, MD Children's Hospital of Philadelphia	Discovering and Targeting Neuroblastoma Vulnerabilities: ALK Inhibition as a Paradigm Watch lecture
03.10.2022	Hongbo Chi, PhD St. Jude Children's Research Hospital	Functional Genomics of T-Cell Metabolism and Immuno-oncology Watch lecture
03.17.2022	Prof. Dr. Stefan M. Pfister Hopp Children's Cancer Center Heidelberg University Hospital	Mapping Childhood Brain Tumor Profiles Onto Normal Development Identifies Novel Therapeutic Vulnerabilities Watch lecture
03.24.2022	Jiyang Yu, PhD St. Jude Children's Research Hospital	Targeting Hidden Drivers Toward Precision Oncology Watch lecture
03.31.2022	Katherine A. Janeway, MD, MMSc Harvard Medical School Dana-Farber Cancer Institute	Learning From Children: Designing Better Clinical Trials with Their Data Watch lecture
04.07.2022	Alejandro Gutierrez, MD Dana-Farber Cancer Institute.	Pathobiology of asparaginase resistance Lecture not archived
04.14.2022	Yutaka Yasui, PhD St. Jude Children's Research Hospital	What Can We Learn From GWAS Data? Genetic Heterogeneity and Rare Variant Hypothesis of Cancer Risk Watch lecture
04.21.2022	Suzanne J. Baker, PhD St. Jude Children's Research Hospital	Disrupted Development in Pediatric High-Grade Glioma Lecture not archived
04.28.2022	Liling Wan, PhD Perelman School of Medicine, University of Pennsylvania Rising Stars of Cancer Research	Reading Epigenetic Landscape: New Mechanisms and Therapeutic Opportunities Lecture not archived
04.29.2022	David Chen, PhD City of Hope Cancer Center	Identify Novel Therapeutic Opportunities in Pediatric Cancers Using High-Resolution CRISPR Tiling Scans Watch lecture
05.05.2022	Jun J. Yang, PhD St. Jude Children's Research Hospital	Unraveling the Heterogeneity of Acute Lymphoblastic Leukemia Through the Lens of Pharmacogenomics Watch lecture
05.12.2022	Lindsay M. Morton, PhD National Cancer Institute	Genetic Susceptibility to Subsequent Neoplasms Following Childhood Cancer Watch lecture
05.19.2022	Charalampos Kalodimos, PhD St. Jude Children's Research Hospital	The Conformational Landscape of Protein Kinases in Physiology and Disease Watch lecture

Date	Speaker	Lecture title
08.12.2021	Charles G. Mullighan, MBBS (Hons), MSc, MD St. Jude Children’s Research Hospital	Deconvoluting the Origins of Acute Leukemia Watch lecture
08.19.2021	Meredith Irwin, MD The Hospital for Sick Children	Identification of Biomarkers, Models and Targets to Improve Outcomes and Precision Approaches for Neuroblastoma Watch lecture
08.26.2021	Olivier Delattre, MD, PhD Institut Curie, Paris, France	Modulation of the Activity of the Dominant Oncogene EWS-FLI1 by Germline Polymorphisms and Cohesin Mutations Watch lecture
09.02.2021	Melissa M. Hudson, MD St. Jude Children’s Research Hospital	The Role of Survivorship Research in Advancing Childhood Cancer Care and Quality of Survival Watch lecture
09.09.2021	Dan A. Landau, MD, PhD Weill Cornell Medical College	Deciphering Somatic Evolution with Single-Cell Multi-Omics Lecture not archived
09.16.2021	David T. Teachey, MD University of Pennsylvania Perelman School of Medicine	The Biology, Diagnosis, and Management of T-Cell Acute Lymphoblastic Leukemia and Lymphoma Watch lecture
09.23.2021	David E. Fisher, MD, PhD Mass General Hospital & Harvard Medical School	Sunlight and Skin: Lessons for Melanoma Therapeutics From Its Unique Pathogenesis Watch lecture
09.30.2021	Matt Vander Heiden, MD, PhD Koch Institute for Integrative Cancer Research at MIT	Influence of Metabolism on Cancer Progression Watch lecture
10.07.2021	Saar Gill, MBBS, PhD, FRACP University of Pennsylvania Perelman School of Medicine Rising Stars of Cancer Research	Chimeric Antigen Receptor-Redirected Macrophages for the Treatement of Solid Tumors Watch lecture
10.07.2021	Yvonne Chen, PhD University of California, Los Angeles Rising Stars of Cancer Research	Engineering Next-Generation CAR-T Cells for Cancer Immunotherapy Lecture not archived
10.14.2021	Bradley Bernstein, MD, PhD Dana-Farber Cancer Institute	Epigenetic Mechanisms of Tumorigenesis Watch lecture
10.21.2021	Mignon Loh, MD Benioff Children’s Hospital, UCSF, San Francisco, CA	What Will it Take To Cure Every Child with Acute Lymphoblastic Leukemia? Watch lecture
10.28.2021	Martin Pule, MB, FRCPath University College London	CAR T Cell Therapies for Childhood Cancer, the University College London Experience Watch lecture
11.04.2021	Kirsten K. Ness, PT, PhD, FAPTA St. Jude Children’s Research Hospital	Interventions to Prevent or Remediate Frailty in Childhood Cancer Survivors Watch lecture
11.11.2021	Giles Robinson, MD St. Jude Children’s Research Hospital Rising Stars of Cancer Research	Tailoring Medulloblastoma Therapy to Fit the Evolving Molecular Landscape Watch lecture
11.11.2021	Mariella Filbin, MD, PhD Dana-Farber Cancer Institute Rising Stars of Cancer Research	Developmental Pathways, Plasticity and Novel Treatment Opportunities in Pediatric High-Grade Brain Tumors Lecture not archived
11.18.2021	Douglas R. Green, PhD St. Jude Children's Research Hospital	Persister Act: Near-Death Experiences in Cancer Cells Lecture not archived

Date	Speaker	Lecture Title
01.28.2021	Jinghui Zhang, PhD St. Jude Children’s Research Hospital	Genomic Variants in Pediatric Cancer: Landscape, Precision Oncology, and Data Sharing Ecosystem Watch lecture
02.04.2021	Richard Gilbertson, MD, PhD University of Cambridge, England	Will We Ever Cure Cancer? Watch lecture
02.11.2021	Scott Armstrong, MD, PhD Dana-Farber/Boston Children’s Cancer and Blood Disorders Center	Chromatin Complexes as Therapeutic Opportunities in Cancer Watch lecture
02.18.2021	Robin Yabroff, PhD, MBA American Cancer Society	Financial Hardship After Childhood Cancer Watch lecture
02.25.2021	John Crispino, PhD, MBA St. Jude Children’s Research Hospital	Mechanisms of Leukemogenesis in Children with Down Syndrome Watch lecture
03.04.2021	Sheila Singh, MD, PhD, FRCS(C) McMaster Children's Hospital, McMaster University	Therapeutic Targeting of Self-Renewal of Medulloblastoma Stem Cells: Strategies for Blocking Recurrence Watch lecture
03.11.2021	Aviv Regev, PhD Genentech	Single Cell Atlases as Roadmaps in Pediatric Cancer Watch lecture
03.18.2021	Douglas S. Hawkins, MD University of Washington School of Medicine	Successes and Challenges in Pediatric Cancer: The COG Perspective Watch lecture
03.25.2021	David T.W. Jones, PhD Hopp Children’s Cancer Center (KiTZ) German Cancer Research Center (DKFZ)	Pediatric High-grade Glioma – Novel Drivers Define a Spectrum of New Tumor Subgroups Watch lecture
04.01.2021	Karen Vousden, PhD The Francis Crick Institute	A Role for Metabolism in Cancer Development and Progression Lecture not archived
04.08.2021	Anne Kirchhoff, PhD, MPH University of Utah/Huntsman Cancer Institute	Identifying Strategies to Improve HPV Vaccination Among Childhood Cancer Survivors Watch lecture
04.15.2021	Madan Babu, PhD, FRSC St. Jude Children’s Research Hospital	Data Science Approaches to GPCR Signaling and Personalized Medicine Watch lecture
04.22.2021	Zhaoming Wang, PhD St. Jude Children’s Research Hospital	Genetic and Epigenetic Approaches Towards Understanding Risk of Chronic Health Conditions Among Survivors of Childhood Cancer Watch lecture
04.29.2021	Kimberly Stegmaier, MD Harvard Medical School Dana-Farber Cancer Institute	A First-generation Pediatric Cancer Dependency Map Watch lecture
05.06.2021	Cigall Kadoch, PhD Harvard Medical School Dana-Farber Cancer Institute	Structure and Function of Mammalian SWI/SNF Chromatin Remodeling Complexes in Human Cancer Watch Lecture

Date	Speaker	Lecture Title
08.14.2020	Michel Sadelain, MD, PhD Memorial Sloan-Kettering Cancer Center	CAR T Cells: On the Road to Synthetic Immunity Watch lecture
08.20.2020	Charles W.M. Roberts, MD, PhD St. Jude Children's Research Hospital	Chromatin Remodeler Mutations in Cancer: Mechanisms and Therapeutic Vulnerabilities Watch lecture
08.27.2020	Terry J. Fry, MD University of Colorado School of Medicine	The Future of CAR T Cells for Hematologic Malignancies: Beyond Antigen Targeting Watch lecture
09.03..2020	Richard W. Kriwacki, PhD St. Jude Children's REsearch Hospital	Phase Separation in Gene Transcription: From the Nucleolus to Aberrant Transcription in Leukemia Watch lecture
09.10.2020	Smita Bhatia, MD, MPH School of Medicine, University of Alabama at Birmingham	Late Effects Among Survivors of Blood or Marrow Transplantation Watch lecture
09.17.2020	Christine Brown, PhD City of Hope	Advancing CAR T Cells for the Treatment of Glioblastoma: Progress and Challenges Lecture not archived
09.24.2020	Kevin R. Krull, PhD St. Jude Children's Research Hospital	Cognitive Outcomes of Childhood Cancer: Neurophysiology, Biomarkers and Interventions Watch lecture
10.01.2020	Iannis Aifantis, PhD New York University Grossman School of Medicine	3D Chromosomal Organization in Pediatric Leukemia: Impact for Drug Response and Disease Progression Watch lecture
10.08.2020	Paul A. Northcott, PhD St. Jude Children's Research Hospital	Medulloblastomics 2020: Biological & Clinical Insights From 1,000s of Patients Watch lecture
10.15.2020	Crystal Mackall, MD Stanford University	CAR T Cells for Pediatric Cancers: Progress and Challenges Watch lecture
10.22.2020	Richard A. Young, PhD Massachusetts Institute of Technology Isaac A. Klein, MD, PhD Dana-Farber Cancer Institute	Partitioning of Cancer Therapeutics in Nuclear Condensates Watch lecture
10.29.2020	Rani George, MD, PhD Harvard Medical School Dana-Farber Cancer Institute	Harnessing Lineage Plasticity for the Treatment of Neuroblastoma Watch lecture
11.05.2020	Paul G. Thomas, PhD St. Jude Children's Research Hospital	Organized Destruction and Destructive Organization: The Diversity of Immune Responses Towards Tumors and Pathogens Watch lecture
11.12.2020	Michelle Monje, MD, PhD Stanford University	Targeting Neuron-Glial Interactions in Childhood Brain Cancer Watch lecture
11.19.2020	Eric Chow, MD, MPH Fred Hutchinson Cancer Research Center	Emerging Late Effects of Targeted Molecular Therapies Watch lecture

Register for the lecture series

Full Name*

Email*

Institution*

Country*

Position*

Comprehensive Cancer Center

St. Jude is the first and only National Cancer Institute-designated Comprehensive Cancer Center devoted solely to children.

Explore the center

Close