The Department of Immunology at St. Jude is committed to understanding the fundamental cell biology of the immune system. This complex network of processes and players is key to defending the body from infection and disease. By deciphering the identity, development, and regulation of the immune system, our researchers are able to build a deeper understanding of normal and pathologic function.
Led by Dr. Doug Green, the Department of Immunology is home to venerated icons, rising stars, and pivotal players in the field. Our investigators are world leaders in innate and adaptive immunity with access to outstanding departmental cores and cutting-edge technologies. We leverage close ties to clinical scientists and experts in human cancer and immunotherapy forming collaborative and innovative teams. The Department also benefits from highlight skilled computational support that maintains an in depth understanding of immunology.
Investigating the mechanisms of immune cell metabolism in T cell biology, systems immunology and human disease
Deciphering epigenetic control of T cell repertoire diversity and function
Discovering key processes of cell death, survival, and regulation of immune responses
Investigating inflammasomes and inflammatory cell death, PANoptosis, in infectious and inflammatory disease and cancer
Dissecting the regulation of the immune system and optimizing its context-specific response
Decoding the immune response to explain human health and disease
Exploring epigenetic regulation of T cell adaptive immunity
The Immunologic Imaging center offers a range of microscopic techniques, including super resolution microscopy (STORM and SoRa), live cell microscopy, expansion microscopy, and other methodologies.
Cliff Guy, PhD - Director of Lab Operations
The Department of Immunology houses a fully equipped flow cytometry facility with extensive capability for fluorescent sorting and analysis with high dimensionality.
Richard Cross, PhD – Director of Lab Operations
Greig Lennon, PhD – Scientist
Katie Hays – Researcher
Soghra Fatima, PhD – Lead Researcher
The Immunological Reagents core is a fully equipped facility for monoclonal antibody and tetramer preparation and provides assistance in genetic engineering of cells and mice.
Scott Brown, PhD – Director of Lab Operations
Emin Kuliyev, PhD – Lead Researcher
The Immunometabolism core offers targeted metabolomics, metabolic tracing, and mitochondrial metabolism assays with a focus on the cells of the immune system.
Gustavo Palacios, PhD – Research Operations Manager
The Administrative Core oversees the daily functions of the Department of Immunology. Responsibilities include coordination of departmental activities, grant preparation and management, and the purchase and maintenance of common equipment.
Elvia Oliva, MBA – Administrative Director
Mitzi Atchison – Senior Administrative Assistant
Casey Deakins – Grants and Contracts Coordinator
Akiah Jones, MBA – Administrative Specialist
Shandy Lewis, MA – Senior Administrative Specialist
Linda Orman – Administrative Specialist
St. Jude investigators have the freedom to focus on making big discoveries, backed by extraordinary resources and support teams. We are always looking for highly motivated scientists and engineers with passion and talent to join us!