2021 Archive

Pharmaceutical Sciences

The circuitous path from chemical compound to clinical trial

Heather Johnson

St. Jude scientists are making progress in the treatment of pediatric cancer by translating new drug findings from the lab to the clinic.

Profiles

5 Questions for Andrew Kleist, MD, PhD

Andrew Kleist, MD, PhD and Alex Generous, PhD

Meet Andew Kleist, MD, PhD, a 2025 STAT Wunderkind early career scientist.

Research

Genomic Medicine Initiative (GEMINI) targets unmet needs in rare disease treatment

Jake Hopkins, MBA and Brian O'Flynn, PhD

Learn how GEMINI addresses the challenges of rare genetic diseases

Profiles

Navigating a non-traditional path to becoming a scientist

Matthew Fisher

Meet graduate student Matthew Fisher to learn about his atypical scientific career progression.

Survivorship

St. Jude calculators crunch the numbers to empower survivors of childhood cancer

Alex Generous, PhD

Find about these free resources, which scientists keep current with the most current survivorship research.

Profiles

Finding my path from baseball to biomedical science

Jordan Bondrowski

A chance encounter at a baseball game as a child set Jordan Bondrowski on the path toward becoming a student in the St. Jude Graduate School of Biomedical Sciences.

Research

Demystifying a methylation mystery at the fetal hemoglobin gene promoter

Alex Generous, PhD

Learn how St. Jude scientists answered a decades-old mystery with implications for sickle cell anemia and beta thalassemia treatment.

Imaging

Harnessing the power of PET to diagnose infectious disease

Kathryn J. McCullough, MA

In a first-in-human trial, investigators at St. Jude are using the power of PET paired with novel radiotracer, [18F]fluoromannitol, to diagnose bacterial infections in patients.

Profiles

5 Questions for Vivian Lawrence, RN

Vivian Lawrence, RN and Kathryn J. McCullough, MA

Meet Vivian Lawrence, RN, Department of Pediatric Medicine, and learn about her career path in clinical research at St. Jude.

Immunotherapy

Center of Excellence in Pediatric Immuno-Oncology fast-tracks progress from the lab to the clinic

Alex Generous, PhD

Learn how St. Jude is accelerating immunotherapy research through communication.

Research

The heart of the matter – cancer survivors and heart disease

Matthew J. Ehrhardt, MD

Cancer treatments can result in damage to the heart both during treatment and years following completion of therapy. As many cancer survivors are now living longer into adulthood, we’re gaining a better understanding of some of the late effects of cancer treatments that we weren’t able to observe before.

Research

Immune markers offer clues to antibody production in response to flu

Mary Powers

Scientists are learning more about antibody production in response to flu, including how they develop from helper T cells and monocytes.

Clinical

Cancer care during a pandemic: What we learned prepares us for the next emergency

Dylan Graetz, MD, MPH

The pandemic exposed shortcomings in health care. But this study revealed more than expected in this type of children’s treatment.

Outreach

Learning the value of mentors, champions and building a strong network

St. Jude Progress

Tangie Thomas, MPH, is vice president of Clinical Trials Operations at St. Jude Children’s Research Hospital.

Investigator Insights

Jasmine Turner: Overcoming obstacles, rising to meet challenges

Mike O’Kelly

For Jasmine Turner, resilience and tenacity were required to enter a field with very few Black women. There weren’t many women or teachers of color in her scientific courses—no one with similar experiences to help guide her or focus her talents. She turned to her mother for encouragement and inspiration.

Clinical

What we’ve found out about hearing loss and cognitive function in children

Johnnie Bass, AuD, PhD

This study, to our knowledge, is the first to objectively measure hearing and neurocognitive function in a large cohort of long-term survivors of childhood cancer stratified by treatment exposures.

Investigator Insights

Making purposeful connections to help others grow and develop

Chris Pennington

Andrea Stubbs shares her experiences that shaped her career in community outreach to raise awareness for both HIV and HPV.

Investigator Insights

Leadership begins where the comfort zone ends

St. Jude Progress

Women of St. Jude highlights the influences and events that shaped the career of Pat Keel, who shares lessons she’s learned about teamwork and leadership.

Clinical

The global burden of sickle cell disease: The quality of treatment shouldn’t depend upon where you live

Ayobami Olanrewaju, MD

Survival and quality of life for many with sickle cell disease depends upon where they live. Here’s what a doctor wants to do to fix that.

Clinical

How do fathers grieve the loss of a child?

Michael J. McNeil, MD

Fathers express grief through keeping busy or focusing on work – different than a mother’s grief. But fathers may not be getting the support they need after the loss of a child.