St. Jude Clinical Trials
BMR: Bone Marrow Collection for Sickle Cell and Thalassemia Research
Diseases Treated:
Sickle cell anemia, thalassemia
Eligibility:
This is a non-therapeutic clinical trial that is only open to St. Jude patients.
- At least 2 years old
- Diagnosed with sickle cell anemia or thalassemia
- No active disease, including painful crisis or active infection
- Adequate blood counts
ExAMS: Medication Adherence in Children with Sickle Cell Disease
Diseases Treated:
Non-therapeutic
Eligibility:
This clinical trial is open only to patients at the St. Jude Children’s Research Hospital Hematology Clinic.
- Diagnosis of sickle cell disease (SCD)
- At least 12 years old and younger than 18 years old
- On a stable hydroxyurea dose in pill formation for 6 months or longer
- Lives with legal guardian
- Able to return to clinic at 4-week intervals
INSIGHT-HD: Investigating the Genetics of Hematologic Diseases
Diseases Treated:
Non-malignant blood diseases (non-therapeutic)
Eligibility:
- Receiving therapy or a consultation for a non-malignant blood disorder
- Biological relatives (with or without a non-malignant blood disorder) who agree to undergo genetic testing
LEAPS: Understanding Sickle Cell Disease Transition to Adult Care
Diseases Treated:
Eligibility:
This is a non-therapeutic study for patients at St. Jude Children’s Research Hospital and Methodist Adult Comprehensive Sickle Cell Center.
- Diagnosis of sickle cell disease (SCD)
- 16 to 20 years old
- English is primary language
PMVOCVR: Virtual Reality Therapy for Vaso-Occlusive Crisis in Patients with Sickle Cell Disease
Diseases Treated:
Eligibility:
This is a non-therapeutic clinical trial that is open only to patients at St. Jude or Methodist Healthcare.
- Between 6 and 25 years old
- Diagnosed with sickle cell disease
- Seeking care for acute vaso-occlusive crisis pain at St. Jude Children’s Research Hospital or Methodist Healthcare
- Speaks English
SCCRIP: Sickle Cell Research and Intervention Program
Diseases Treated:
Eligibility:
This is a non-therapeutic clinical trial that is only open to St. Jude patients.
- Participant has a diagnosis of Sickle Cell Disease of any genotype.
Collaborative Clinical Trials
BHEEM: Study of BEAM-101 in Patients with Severe Sickle Cell Disease
Diseases Treated:
Eligibility:
- 18 to 35 years old
- Diagnosed with severe sickle cell disease