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Sickle Cell Disease Clinical Trials

 

St. Jude Clinical Trials

BMR : Bone Marrow Collection for Sickle Cell and Thalassemia Research (closed to accrual)

Diseases Treated:

Sickle cell anemia, thalassemia

Eligibility:

This is a non-therapeutic clinical trial that is only open to St. Jude patients.

  • At least 2 years old
  • Diagnosed with sickle cell anemia or thalassemia
  • No active disease, including painful crisis or active infection
  • Adequate blood counts
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INSIGHT-HD: Investigating the Genetics of Hematologic Diseases

Diseases Treated:

Non-malignant blood diseases (non-therapeutic)

Eligibility:

  • Receiving therapy or a consultation for a non-malignant blood disorder
  • Biological relatives (with or without a non-malignant blood disorder) who agree to undergo genetic testing
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LEAPS: Understanding Sickle Cell Disease Transition to Adult Care

Diseases Treated:

Sickle Cell Disease

Eligibility:

This is a non-therapeutic study for patients at St. Jude Children’s Research Hospital and Methodist Adult Comprehensive Sickle Cell Center.

  • Diagnosis of sickle cell disease (SCD)
  • 16 to 20 years old
  • English is primary language
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PMVOCVR: Virtual Reality Therapy for Vaso-Occlusive Crisis in Patients with Sickle Cell Disease

Diseases Treated:

Sickle cell disease

Eligibility:

This is a non-therapeutic clinical trial that is open only to patients at St. Jude or Methodist Healthcare.

  • Between 6 and 25 years old
  • Diagnosed with sickle cell disease
  • Seeking care for acute vaso-occlusive crisis pain at St. Jude Children’s Research Hospital or Methodist Healthcare
  • Speaks English
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SCCRIP: Sickle Cell Research and Intervention Program

Diseases Treated:

Sickle cell disease

Eligibility:

This is a non-therapeutic clinical trial that is only open to St. Jude patients.
  • Participant has a diagnosis of Sickle Cell Disease of any genotype.
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SCDCogO2: Analyzing Oxygen Saturation and Neurocognitive Functioning in Patients with Sickle Cell Disease

Diseases Treated:

Non-therapeutic

Eligibility:

This is a non-therapeutic clinical trial that is only open to St. Jude patients.

St. Jude Patients

  • 8 to 17 years old 
  • Sickle cell anemia 
  • Enrolled on the Sickle Cell Clinical Research Intervention Program (SCCRIP) clinical trial 
  • Completed Sickle Cell Assessment of Neuropsychology Skills (SCANS) assessment 
  • Being treated with hydroxyurea
  • Read and speak English

Siblings

  • Siblings of St. Jude patients with sickle cell disease 
  • Do not have sickle cell disease 
  • 8 to 17 years old 
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Collaborative Clinical Trials

BHEEM: Study of BEAM-101 in Patients with Severe Sickle Cell Disease

Diseases Treated:

Sickle Cell Disease

Eligibility:

  •  18 to 35 years old
  • Diagnosed with severe sickle cell disease
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