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BMR: Bone Marrow Collection for Sickle Cell and Thalassemia Research

About this study

Sickle cell anemia is an inherited disease primarily affecting individuals of African American descent. It can both shorten and reduce the quality of life by creating risk for strokes and causing chronic organ damage.

Gene therapy may potentially address the lack of available healing therapy. This study will use bone marrow stem cells from patients with sickle cell disease or thalassemia. Stem cells are able to become any type of blood cell. They usually live in the bone marrow.

If you participate in this study, you will be asked to donate stem cells. Researchers will collect your cells by taking a sample of your liquid marrow through a needle. This procedure is known as bone marrow aspiration.

Eligibility overview

  • At least 2 years old
  • Diagnosed with sickle cell anemia or thalassemia
  • No active disease, including painful crisis or active infection
  • Adequate blood counts

The above information is intended to provide only a basic description about a research protocol that may be currently active at St. Jude. The details made available here may not be the most up-to-date information on protocols used by St. Jude. To receive full details about a protocol and its status and or use at St. Jude, a physician must contact St. Jude directly.


Full title:

Bone Marrow for Hemoglobinopathy Research

Study goal:

The main goal of this study is to explore new treatments for sickle cell disease and thalassemia.


At least 2 years old

For physicians and researchers

Patients accepted to St. Jude must be referred by a physician or other qualified medical professional. Learn how St. Jude can partner with you to care for your patient.


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