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CATCHASCVD: Heart Health in Childhood Cancer Survivors

About this study 

Childhood cancer survivors can have heart and blood vessel problems after treatment ends. Radiation therapy and chemotherapy can increase this risk. But current tests may not identify younger survivors who are more likely to develop these problems. 

The CATCHASCVD study looks for early signs of heart and blood vessel disease. Those who take part will have: 

  • A computed tomography (CT) scan of the chest to look for early signs of blood vessel disease 
  • A blood test 
  • An ultrasound of their neck to look for narrowing of the vessels 
  • Tests to see how well their blood vessels work 

People in this study are also part of the St. Jude Lifetime Cohort (SJLIFE). Researchers will compare results from childhood cancer survivors with results from those who have not had cancer. 

We hope to learn which tests can help find survivors at higher risk for heart and blood vessel disease. This information may help improve future screening and care. 

Eligibility overview 

  • Age 18 or older 
  • Enrolled in SJLIFE 
  • Childhood cancer survivor who had chest or neck radiation and certain chemotherapy 
  • No previous heart attack or stroke 
  • No previous treatment for severe heart or blood vessel disease 

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The above information is intended to provide only a basic description about a research protocol that may be currently active at St. Jude. The details made available here may not be the most up-to-date information on protocols used by St. Jude. To receive full details about a protocol and its status and or use at St. Jude, a physician must contact St. Jude directly.

Overview

Full title:

CATCHASCVD: Clinical Assessment and Targeted Imaging to Characterize High-risk Atherosclerotic Cardiovascular Disease of Survivors in SJLIFE

Study goal:

To study heart and blood vessel health and improve the early detection of heart disease in childhood cancer survivors

Diagnosis:

Childhood cancer

Age:

18 years and older

Clinical trial categories:

Childhood Cancer

For physicians and researchers

Patients accepted to St. Jude must be referred by a physician or other qualified medical professional. Learn how St. Jude can partner with you to care for your patient.

 

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