St. Jude Care & Treatment

Menu

Close

Recruiting

CRIMSON2: Cardiac MRI Predictors for Sepsis in Cancer

About this study

Some cancer patients may develop a serious condition called sepsis. Sepsis happens when the body reacts to an infection in a way that harms its own organs. One of the organs that sepsis may affect is the heart.

The usual way of detecting heart issues in patients with sepsis is to give them a physical exam, blood tests, an electrocardiogram (EKG or a picture of the heart), and an echocardiogram (ultrasound of the heart).

This study will use another way to take pictures of the heart known as a cardiac magnetic resonance (CMR), also known as cardiac MRI. This method does not use radiation and may better detect changes in the heart and the way it works.

Young patients with cancer who have sepsis will be studied with CMR. The first phase of the study will take pictures of their hearts shortly after they develop sepsis. The next phase will follow the patients to watch for changes in their heart and the way it works. Patients will have a repeat CMR months later.

This study may help doctors better understand the effects of sepsis on heart function in children with cancer and may help predict who is at risk for heart problems from sepsis.

Eligibility overview

  • 9–25 years old
  • St. Jude cancer patient
  • Diagnosed with sepsis

Request a referral

The above information is intended to provide only a basic description about a research protocol that may be currently active at St. Jude. The details made available here may not be the most up-to-date information on protocols used by St. Jude. To receive full details about a protocol and its status and or use at St. Jude, a physician must contact St. Jude directly.

Overview

Full title:

Cardiovascular Magnetic Resonance Prognosticators in Pediatric Oncology Patients with Sepsis: A Pilot Study (CRIMSON2)

Study goal:

To study the use of cardiac MRI to detect changes in the heart and its function in pediatric cancer patients with sepsis.

Diagnosis:

Cancer and sepsis

Age:

9–25 years

Clinical trials categories:

Childhood Cancer

For physicians and researchers

Patients accepted to St. Jude must be referred by a physician or other qualified medical professional. Learn how St. Jude can partner with you to care for your patient.

 

Learn more