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NEUFEED: Brain Training for Medulloblastoma Survivors

About this study 

Medulloblastoma survivors can have problems with memory, attention, and learning after cancer treatment. These problems can make school and daily life harder. This study looks at a new way to improve memory and thinking skills in medulloblastoma survivors. 

NEUFEED tests a type of brain training that allows researchers to study brain function while people do memory tasks. Researchers hope this training can help improve working memory. Working memory is a type of memory that helps people remember and use information for a short time. For example, it helps a person follow directions with several steps. 

Children and young adults in the study are placed into 1 of 2 groups by chance. One group gets brain training for memory while the other gets a different type of brain training. 

Participants have 3 study visits over about 10 days to 3 weeks. They complete memory and thinking tests and answer questions about side effects. During the first 2 visits, they do training while inside an MRI scanner. During the third visit, they do brain training with a cap with sensors that measure brain activity. Parents or caregivers will also answer questions about the participant’s daily thinking and behavior. 

Researchers want to learn whether:  

  • This type of brain training is well tolerated 
  • People can complete it 
  • It increases brain activity to improve thinking 
  • It can help medulloblastoma survivors improve memory and thinking skills  
  • It should be tested in a larger study 

Eligibility overview 

  • 10–25 years old 
  • Current or former St. Jude patient treated with craniospinal radiation for medulloblastoma 
  • Completed medulloblastoma treatment at least 2 years ago 
  • Has working-memory problems based on a screening questionnaire 

Request a referral

The above information is intended to provide only a basic description about a research protocol that may be currently active at St. Jude. The details made available here may not be the most up-to-date information on protocols used by St. Jude. To receive full details about a protocol and its status and or use at St. Jude, a physician must contact St. Jude directly.

Overview

Full title:

NEUFEED: Cognitive Rehabilitation for Survivors of Childhood Medulloblastoma Using Real-time Hemodynamic Neurofeedback

Study goal:

To study neurofeedback training to improve memory and thinking skills in survivors of childhood medulloblastoma

Diagnosis:

Medulloblastoma

Age:

10–25 years

Clinical trial categories:

Medulloblastoma Brain Tumors Childhood Cancer

For physicians and researchers

Patients accepted to St. Jude must be referred by a physician or other qualified medical professional. Learn how St. Jude can partner with you to care for your patient.

 

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