Clinical trials are a type of scientific research. They can help scientists learn about diseases and treatments in people. Patients who take part in our clinical trials, and their families, should have access to the results of that research.
Research often takes a long time, so many years may pass before results are known.
Learn more about taking part in clinical research >
Study results are often published in scientific and medical journals. St. Jude or another organization may also publish a notice about the results. If your clinical trial is not listed here, the study results may not yet be available. Be sure and check back later. After study results are published, the summaries will be posted here.
We offer our patients a simple summary that shows what we learned from the study. You can also ask your doctor or research participant advocate about the study. To reach the advocate, call 901-595-4644. If you are outside the Memphis area, dial 1-866-JUDE IRB (1-866-583-3472).
Each summary includes the name of the study, why the study was done, when the study took place and what we learned. It also gives details on the next research steps, how the study affected your child and where to learn more.
View recent clinical trial results below:
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Brain Tumor Clinical Trials
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SJHG12
Study of the Combination of Crizotinib and Dasatinib in Pediatric Research Participants with Diffuse Pontine Glioma and High-Grade Glioma
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SJMB03
Treatment of patients with newly diagnosed medulloblastoma, supratentorial primitive neuroectodermal tumor, or atypical teratoid rhabdoid tumor.
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SJMB12
A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma.
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SJPDGF
PDGFR Inhibitor Crenolanib in Children/ Young Adults with Diffuse Intrinsic Pontine Glioma or Recurrent High-Grade Glioma (SJPDGF)
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SJYC07
Risk-adapted therapy for young children with medulloblastoma.
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Infectious Diseases Clinical Trials
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BUZZOFF
Phase 1a, First-in-human, Dose-escalation Study of (+)-SJ000557733 (SJ733), an Oral, Novel Inhibitor of Plasmodium Falciparum Plasma Membrane Protein PFATP4.
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ETHEL
Ethanol Lock Therapy for Treatment and Secondary Prophylaxis of Central Line-Associated Bloodstream Infection.
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CARMA
Catheter Resistance Monitoring to Predict Catheter-Associated Adverse Events in Children and Adolescents.
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Leukemia Clinical Trials
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AML02
A Collaborative Trial for the Treatment of Patients with Newly Diagnosed Acute Myeloid Leukemia or Myelodysplasia.
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AML08
A Phase III Randomized Trial of Clofarabine Plus Cytarabine Versus Conventional Induction Therapy and A Phase II Study of Natural Killer Cell Transplantation in Patients with Newly Diagnosed Acute Myeloid Leukemia
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BECHEM
A Phase I Trial of Bendamustine in Combination with Clofarabine and Etoposide in Pediatric Patients with Relapsed or Refractory Hematologic Malignancies.
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Genomes for Kids G4K
Genomes for Kids, or G4K, is a research study for children with cancer. The main goal of the study was to see if doctors at St. Jude could use NGS to learn more about the genes in children’s cancer and also in their healthy cells.
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HLHR13
Adcetris (Brentuximab Vedotin), Combination Chemotherapy, and Radiation Therapy in Treating Younger Patients With Stage IIB, IIIB and IV Hodgkin Lymphoma.
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REFLEX
Haploidentical Hematopoietic Stem Cell Transplantation Using A Novel Clofarabine Containing Conditioning Regimen For Patients With Refractory Hematologic Malignancies.
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SELHEM
Testing the addition of a new drug, selinexor (KPT-330), to chemotherapy in patients with advanced leukemia or myelodysplastic syndrome.
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SJCAR19
A Phase I/II Study Evaluating SJCAR19 (CD19-Specific CAR Engineered Autologous T-Cells) in Pediatric and Young Adult Patients ≤ 21 Years of Age With Relapsed or Refractory CD19+ Acute Lymphoblastic Leukemia (SJCAR19)
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TOTXV
TOTAL Therapy Study XV for Newly Diagnosed Patients with Acute Lymphoblastic Leukemia.
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TOTXVI
TOTAL Therapy Study XVI for Newly Diagnosed Patients with Acute Lymphoblastic Leukemia.
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VENAML
A Phase I and Expansion Cohort Study of Venetoclax in Combination with Chemotherapy in Pediatric Patients with Refractory or Relapsed Acute Myeloid Leukemia.
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Sickle Cell Disease Clinical Trials
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Solid Tumor Clinical Trials
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Genomes for Kids G4K
Genomes for Kids, or G4K, is a research study for children with cancer. The main goal of the study was to see if doctors at St. Jude could use NGS to learn more about the genes in children’s cancer and also in their healthy cells.
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NB2012
Neuroblastoma Protocol 2012: Therapy for Children with Advanced Stage High-Risk Neuroblastoma
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OS2008
A study of bevacizumab, a humanized monoclonal antibody against vascular endothelial growth factor (VEGF), in combination with chemotherapy for treatment of osteosarcoma.
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RADBEV
A Phase I Trial of RAD001 (Everolimus) and Avastin (Bevacizumab) in Children with Recurrent Solid Tumors.
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RET5
Study of Treatment for Patients with Cancer of the Eye—Retinoblastoma.
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SJGD2NK & PATA
A safety/feasibility trial of the addition of the humanized anti-GD2 antibody (HU14.18K322A) with and without natural killer cells to chemotherapy in children and adolescents with recurrent/refractory neuroblastoma (SJGD2NK) and pretreatment anti-therapeutic antibodies (PATA) in patients treated with HU14.18K322A antibody.
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