Bone Marrow Transplant Clinical Trials

Diseases Treated:

• Acute lymphoblastic leukemia
• Acute myeloid leukemia
• Myelodysplasia
• Hodgkin lymphoma
• Non-Hodgkin lymphoma
• Juvenile myelomonocytic leukemia

Eligibility:

For transplant recipient:

• 21 years or younger
• Does not have a suitable sibling donor or volunteer unrelated donor
• Has a suitable single haplotype matched family member donor
• Diagnosed with high risk hematologic malignancy
• No prior allogeneic hematopoietic cell transplant

Diseases Treated:

• Leukemia
• Lymphoma
• Myeloid sarcoma
• Myelodysplastic syndrome

Eligibility:

• 21 years old and younger
• Diagnosed with one of the following that has come back or did not improve after bone marrow transplant
  • Acute lymphoblastic leukemia (ALL)
  • Acute myeloid leukemia
  • Myeloid sarcoma
  • Chronic myeloid leukemia (CML)
  • Juvenile myelomonocytic leukemia (JMML)
  • Myelodysplastic syndrome (MDS)
  • Non-Hodgkin lymphoma (NHL)
• Has a family member who is a suitable stem cell donor

Diseases Treated:

Severe combined immunodeficiency (SCID)

Eligibility:

• Infant at least 2 months old with severe combined immunodeficiency (SCID)
• Has suitable matched sibling donor or matched unrelated donor or a single haplotype matched family member donor

Diseases Treated:

Acute lymphoblastic leukemia

Eligibility:

• Children and young adults up to 21 years old
• Refractory or relapsed CD19+ acute lymphoblastic leukemia (ALL)