Bone Marrow Transplant Clinical Trials

Diseases Treated:

Acute myeloid leukemia (AML)

Eligibility:

• 21 years of age or younger at the time of study entry
• No prior therapy for AML except for one dose of intrathecal therapy and the use of hydroxyurea or low-dose cytarabine for hyperleukocytosis
• Must not have Down syndrome, acute promyelocytic leukemia (APL), juvenile myelomonocytic leukemia (JMML), Fanconi anemia (FA), Kostmann syndrome, Shwachman syndrome and other  bone marrow failure syndromes

Diseases Treated:

High-risk solid tumors and lymphomas

Eligibility:

• Has a type of high-risk cancer including
  • Neuroblastoma
  • Solid tumors
    
  • Lymphomas
• 21 years of age or younger
• Has not received a prior hematopoietic (blood cells from bone marrow) stem cell transplant within the previous three months

Diseases Treated:

Relapsed or refractory solid tumors or lymphomas

Eligibility:

• Between the ages of 2 and 21 years
• Solid tumor or lymphoma as primary cancer
• Cancer that has come back or did not respond to previous chemotherapy
• No heart, kidney or liver problems

Diseases Treated:

• Leukemia
• Lymphoma
• Myeloid sarcoma
• Myelodysplastic syndrome

Eligibility:

• 21 years old and younger
• Diagnosed with one of the following that has come back or did not improve after bone marrow transplant
  • Acute lymphoblastic leukemia (ALL)
  • Acute myeloid leukemia
  • Myeloid sarcoma
  • Chronic myeloid leukemia (CML)
  • Juvenile myelomonocytic leukemia (JMML)
  • Myelodysplastic syndrome (MDS)
  • Non-Hodgkin lymphoma (NHL)
• Has a family member who is a suitable stem cell donor