Infectious Diseases Clinical Trials

Diseases Treated:

Infectious Disease

Eligibility:

• 2 months old or older
• Diagnosed with adenovirus (AdV) infection
• Has symptoms related to AdV infection
• Able to take and absorb oral medication
• No previous treatment with brincidofovir (BCV)

Diseases Treated:

HIV Infection

Eligibility:

• Participant does not have life expectancy of less than 1 year.
• Participant does not have history of significant drug sensitivity or drug allergy.
• Participant is not participating in any other clinical trial without prior approval from sponsor while participating in this trial.
• Participant does not have an ongoing serious infection requiring systemic antibiotic therapy at the time of screening.

Diseases Treated:

Influenza

Eligibility:

• At least 3 years old and younger than 17
• Allogeneic hematopoietic stem cell transplant recipient
• At least 3 and not more than 35 months after transplant
• Platelet count of at least 30,000

Diseases Treated:

HIV/AIDS

Eligibility:

• Participant is HIV-1 infected male or female aged six (6) to less than eight-teen (18) years of age at Baseline.
• Participant is currently on a stable 2-NRTI (TDF containing) regimen that includes a protocol specified 3rd ARV agent for greater than or equal to six (6) consecutive months prior to screening.
• Participant does not have an acquired immunodeficiency syndrome (AIDS) indicator condition with onset within thirty (30) days prior to screening.

Diseases Treated:

Human Immunodeficiency Virus

Eligibility:

• At least 4 weeks old but younger than 18 years old
• Confirmed HIV-1 infection
• Current or past treatment with HIV medications (Children younger than 2 years old may be eligible even if they have not been treated with HIV medications.)

Eligibility:

• Child is greater than or equal to twelve (12) months and less than twenty-four (24) months.
• Child has adequate blood, liver and kidney function.
• Child has no history of lung disease, asthma, and hospitalization for respiratory illness, immunodeficiency, sickle cell disease, or any other serious underlying condition.