Long-term Effects Clinical Trials

Non-therapeutic protocols address such issues as side effects or long-term effects of therapy, quality of life, making testing easier on the children, prevention of pain, and issues related to nutrition and stress. There are also tissue and blood banking protocols for laboratory researchers who are studying diseases and searching for underlying causes and cures. The research at St. Jude is designed to include all aspects related to the care of sick children and their families.

BMTFU: Protocol for Collecting Long-Term Follow-Up Data on Recipients of Hematopoietic Stem Cell Transplant

Eligibility:

This is a non-therapeutic clinical trial that is only open to St. Jude patients.

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CCSS: Childhood Cancer Survivor Study

Diseases Treated:

Childhood cancer incidence and survival

Eligibility:

This is a non-therapeutic clinical trial that is only open to St. Jude patients.

  • Newly diagnosed with cancer between January 1, 1970, and December 31, 1996
  • Survival five years from diagnosis
  • Age less than 21 years at the time of diagnosis of cancer
  • English or Spanish speaking and living in the United States or Canada at the time of diagnosis
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LTE1621: Pharmacologic Reversal of Ventricular Remodeling in Childhood Cancer Survivors at Risk for Heart Failure (PREVENT-HF): A Phase 2B Randomized Placebo-Controlled (Carvedilol) Trial

Diseases Treated:

Cancer

Eligibility:

  • Younger than 21 years old at time of cancer diagnosis
  • Weigh ≥ 40 Kg
  • Lifetime cumulative anthracycline dose prior to age 22: total dose ≥ 250 mg/m2 DOXOrubicin equivalent without the protection of dexrazoxane (Zinecard) therapy
  • Completed cancer treatment at least 2 years prior to study enrollment
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SJLIFE: Establishment of a Lifetime Cohort of Adults Surviving Childhood Cancer

Eligibility:

This is a non-therapeutic clinical trial that is only open to St. Jude patients.

  • Participant was diagnosed with a childhood cancer which was treated or followed by St. Jude Children's Research Hospital
  • Participant completed treatment for disease at least ten years prior to entry in this study
  • Participant is willing to return to St. Jude for periodic evaluation
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SJLTFU: Protocol for Collecting Data on Childhood Cancer Survivors

Eligibility:

This is a non-therapeutic clinical trial that is only open to St. Jude patients.

  • All patients being followed or treated at St. Jude Children’s Research Hospital for the diagnosis of childhood cancer
  • Patient has not been permanently discharged from care and follow-up
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