St. Jude Clinical Trials
BMR: Bone Marrow Collection for Sickle Cell and Thalassemia Research
Diseases Treated:
Sickle cell anemia, thalassemia
Eligibility:
This is a non-therapeutic clinical trial that is only open to St. Jude patients.
- At least 2 years old
- Diagnosed with sickle cell anemia or thalassemia
- No active disease, including painful crisis or active infection
- Adequate blood counts
INSIGHT-HD: Investigating the Genetics of Hematologic Diseases
Diseases Treated:
Non-malignant blood diseases (non-therapeutic)
Eligibility:
- Receiving therapy or a consultation for a non-malignant blood disorder
- Biological relatives (with or without a non-malignant blood disorder) who agree to undergo genetic testing
LEAPS: Understanding Sickle Cell Disease Transition to Adult Care
Diseases Treated:
Eligibility:
This is a non-therapeutic study for patients at St. Jude Children’s Research Hospital and Methodist Adult Comprehensive Sickle Cell Center.
- Diagnosis of sickle cell disease (SCD)
- 16 to 20 years old
- English is primary language
PMVOCVR: Virtual Reality Therapy for Vaso-Occlusive Crisis in Patients with Sickle Cell Disease
Diseases Treated:
Eligibility:
This is a non-therapeutic clinical trial that is open only to patients at St. Jude or Methodist Healthcare.
- Between 6 and 25 years old
- Diagnosed with sickle cell disease
- Seeking care for acute vaso-occlusive crisis pain at St. Jude Children’s Research Hospital or Methodist Healthcare
- Speaks English
SCCRIP: Sickle Cell Research and Intervention Program
Diseases Treated:
Eligibility:
- Participant has a diagnosis of Sickle Cell Disease of any genotype.
SCDCogO2: Analyzing Oxygen Saturation and Neurocognitive Functioning in Patients with Sickle Cell Disease
Diseases Treated:
Non-therapeutic
Eligibility:
This is a non-therapeutic clinical trial that is only open to St. Jude patients.
St. Jude Patients
- 8 to 17 years old
- Sickle cell anemia
- Enrolled on the Sickle Cell Clinical Research Intervention Program (SCCRIP) clinical trial
- Completed Sickle Cell Assessment of Neuropsychology Skills (SCANS) assessment
- Being treated with hydroxyurea
- Read and speak English
Siblings
- Siblings of St. Jude patients with sickle cell disease
- Do not have sickle cell disease
- 8 to 17 years old
SCDHCT: Reduced Intensity Related Donor HCT for Patients with Severe Sickle Cell Disease
Diseases Treated:
Eligibility:
- 25 years old or younger
- Diagnosed with severe sickle cell disease
- Has a suitable HLA-matched sibling donor or single haplotype matched (half matched) family member donor (parents or siblings)
Collaborative Clinical Trials
BHEEM: Study of BEAM-101 in Patients with Severe Sickle Cell Disease
Diseases Treated:
Eligibility:
- 18 to 35 years old
- Diagnosed with severe sickle cell disease