Sickle Cell Disease Clinical Trials

 

St. Jude Clinical Trials

BMR: Bone Marrow Collection for Sickle Cell and Thalassemia Research

Diseases Treated:

Sickle cell anemia, thalassemia

Eligibility:

This is a non-therapeutic clinical trial that is only open to St. Jude patients.

  • At least 2 years old
  • Diagnosed with sickle cell anemia or thalassemia
  • No active disease, including painful crisis or active infection
  • Adequate blood counts
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INSIGHT-HD: Investigating the Genetics of Hematologic Diseases

Diseases Treated:

Non-malignant blood diseases (non-therapeutic)

Eligibility:

  • Receiving therapy or a consultation for a non-malignant blood disorder
  • Biological relatives (with or without a non-malignant blood disorder) who agree to undergo genetic testing
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LEAPS: Understanding Sickle Cell Disease Transition to Adult Care

Diseases Treated:

Sickle Cell Disease

Eligibility:

This is a non-therapeutic study for patients at St. Jude Children’s Research Hospital and Methodist Adult Comprehensive Sickle Cell Center.

  • Diagnosis of sickle cell disease (SCD)
  • 16 to 20 years old
  • English is primary language
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PMVOCVR: Virtual Reality Therapy for Vaso-Occlusive Crisis in Patients with Sickle Cell Disease

Diseases Treated:

Sickle cell disease

Eligibility:

This is a non-therapeutic clinical trial that is open only to patients at St. Jude or Methodist Healthcare.

  • Between 6 and 25 years old
  • Diagnosed with sickle cell disease
  • Seeking care for acute vaso-occlusive crisis pain at St. Jude Children’s Research Hospital or Methodist Healthcare
  • Speaks English
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SCCRIP: Sickle Cell Research and Intervention Program

Diseases Treated:

Sickle cell disease

Eligibility:

This is a non-therapeutic clinical trial that is only open to St. Jude patients.
  • Participant has a diagnosis of Sickle Cell Disease of any genotype.
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Collaborative Clinical Trials

TADO: A Study of Prasugrel in Pediatric Participants With Sickle Cell Disease (SCD)

Diseases Treated:

Sickle cell disease

Eligibility:

  • Participant with Sickle Cell Disease (laboratory determined HbSS or HbS beta zero thalassemia) who have had >2 episodes of Vaso-occlusive crisis in the past year. 
  • Participants >2 years of age and < 18 years of age.
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