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Supportive Leukemias / Lymphomas Studies

Non-therapeutic protocols address such issues as side effects or long-term effects of therapy, quality of life, making testing easier on the children, prevention of pain, and issues related to nutrition and stress. There are also tissue and blood banking protocols for laboratory researchers who are studying diseases and searching for underlying causes and cures. The research at St. Jude is designed to include all aspects related to the care of sick children and their families.

St. Jude Clinical Trials

APNEA: Sleep Apnea in Hodgkin Lymphoma Survivors Treated with Radiation to the Chest

Diseases Treated:

Hodgkin lymphoma

Eligibility:

Hodgkin lymphoma survivor

  • Patient eligible for the St. Jude LIFE study
  • Treated with thoracic radiation for Hodgkin lymphoma
  • At least 18 years old
  • At least 5 years from original diagnosis
  • If participating remotely, must have Wi-Fi access

Comparison group

  • Non-patient volunteer (Cannot be sibling, parent or child of the survivor participant)
  • At least 18 years old
  • Lives in the U.S.
  • If participating remotely, must have Wi-Fi access
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DSCOG: Learning, Behavior and Social Skills in Survivors of Childhood Leukemia with Down syndrome

Diseases Treated:

Leukemia

Eligibility:

This is a non-therapeutic clinical trial that is open only to patients who were treated at St. Jude Children’s Research Hospital since 1980 and are currently followed at the hospital.

  • St. Jude Children’s Research Hospital patient with acute leukemia (i.e., ALL or AML)
  • Trisomy 21 Down syndrome diagnosis
  • Completed all cancer therapy at St. Jude since 1980 and at least six months prior to study visit
  • English as the primary language
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G4K: Genomes for Kids

Diseases Treated:

Non-therapeutic

Eligibility:

This is a non-therapeutic clinical trial that is open to St. Jude patients.

  • Solid tumor or liquid tumor (cancerous or non-cancerous)
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Collaborative Clinical Trials

ALTE1631: Web-based Exercise Study for Children and Adolescents with Cancer

Diseases Treated:

leukemia, solid tumor, brain tumor, lymphoma, carcinoma

Eligibility:

This is a non-therapeutic clinical trial open to patients receiving treatment at a Children’s Oncology Group (COG)-affiliated institution.

  • At least 8 years old and younger than 16 years old
  • Diagnosed with childhood cancer, in remission
  • Completed therapy within the past 12 months
  • Performance status corresponding to ECOG scores of 0, 1, 2
  • Fewer than 420 minutes of moderate to vigorous physical activity (MVPA) over the last week
  • Able to write and read English, Spanish or French (patient and at least one parent/guardian)
  • Not pregnant
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NCBP01: Safety Study of Unlicensed, Investigational Cord Blood Units Manufactured by the NCBP for Unrelated Transplantation

Diseases Treated:

Leukemia and other blood diseases

Eligibility:

This is a non-therapeutic clinical trial that is only open to St. Jude patients.

  • Participant is receiving an allogeneic hematopoietic stem cell (HSC) transplant at St. Jude Children's Research Hospital using an unlicensed cord blood unit (CBU).
  • Participant may be of any age and either gender.
  • Participant has a medical disorder affecting the hematopoietic system that is inherited, acquired, or a result from myeloablative treatment.
  • Participant is receiving HPC-CORD BLOOD product manufactured by NCBP (at least one, if the graft contains more than one units).
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