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Supportive Solid Tumor Studies

Non-therapeutic protocols address such issues as side effects or long-term effects of therapy, quality of life, making testing easier on the children, prevention of pain, and issues related to nutrition and stress. There are also tissue and blood banking protocols for laboratory researchers who are studying diseases and searching for underlying causes and cures. The research at St. Jude is designed to include all aspects related to the care of sick children and their families.

St. Jude Clinical Trials

DWSARC: Diffusion Weighted Magnetic Resonance Imaging In Pediatric Sarcomas

Diseases Treated:

Solid tumors

Eligibility:

This is a non-therapeutic clinical trial that is only open to St. Jude patients.

  • Participant is under the care of a St. Jude physician with a known or suspected, newly diagnosed bone or soft tissue sarcoma who will be treated on or as per disease specific protocols and has not begun therapy OR participant has started therapy and the needed research imaging can be performed within 2-5 days of starting treatment. 
  • Participant has undergone or is scheduled for PET-CT, Bone Scan, or PET-CT and Bone Scan within two (2) weeks of the whole body and primary tumor DWI-MRI. 
  • Participant meets institutional MRI safety screening requirements. 
  • Participant has not undergone primary tumor resection prior to arrival to St. Jude
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G4K: Genomes for Kids

Diseases Treated:

Non-therapeutic

Eligibility:

This is a non-therapeutic clinical trial that is open to St. Jude patients.

  • Solid tumor or liquid tumor (cancerous or non-cancerous)
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IPACTR: International Pediatric Adrenocortical Tumor Registry

Diseases Treated:

Adrenocortical tumors (carcinoma and adenoma)

Eligibility:

  • Diagnosis of an adrenocortical tumor (ACT)
  • 21 years of age or younger at diagnosis
  • Relatives of patients with ACT
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U-CHAT: Understanding Communication in Health Care to Achieve Trust

Diseases Treated:

Non-therapeutic

Eligibility:

Primary oncologist:

  • Attending physician age 18 years or older who provides medical care to patients in the Solid Tumor or Neuro-Oncology Clinics at St. Jude Children’s Research Hospital
  • Primary hematology-oncology fellows age 18 or older (audio-recorded disease reevaluation only)

Parents of children with cancer:

  • Age 18 or older
  • Biological parent, step-parent or primary legal guardian
  • Reads and speaks English

Patients:

  • Primary oncologist is enrolled in the study.
  • 30 years old or younger
  • Diagnosed with a solid tumor and/or a brain tumor
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Collaborative Clinical Trials

MACMEL: A Study to Analyze Melanoma Lesions in Children and Teens

Diseases Treated:

Melanoma

Eligibility:

  • Diagnosed with a melanoma tumor that is malignant (cancerous) or that might be cancerous, including:
    • Conventional or “adult-type” melanoma
    • Spitzoid melanoma/atypical Spitz tumor
    • Congenital melanoma
    • Melanoma arising in a giant congenital nevus
    • Melanocytic lesions with indeterminate biological behavior (e.g., pigment-synthesizing melanomas)
  • Younger than 19 years of age 
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