St. Jude Research

Comprehensive Cancer Center

St. Jude Children’s Research Hospital has the first and only National Cancer Institute-designated Comprehensive Cancer Center devoted solely to children.

About us

Sara Federico

The mission of the St. Jude Comprehensive Cancer Center (SJCCC) is to advance cures for pediatric cancer through research and treatment. We are the nation’s only NCI-designated Cancer Center dedicated exclusively to pediatric cancer.

Our designation as a Comprehensive Cancer Center reflects leading excellence in laboratory, clinical and survivorship research, as well as leadership in education and community outreach. The center has received the highest possible score of “exceptional” in its three most recent NCI reviews.

Director Charles W. M. Roberts, MD, PhD, a long-standing advocate of team science, leads the Center with a strong vision: To bring about a future in which every child with cancer can look forward to a long and healthy life. The Center aims to improve outcomes and understanding of pediatric cancer to benefit patients and survivors in our catchment area, and to extend these findings to the nation and the world.

  • Research

    The Comprehensive Cancer Center aims to improve outcomes and understanding of pediatric cancer to benefit patients and survivors.

  • Clinical Care

    St. Jude is one of the world’s leading childhood cancer research and treatment centers. Learn how we are helping more children survive and thrive.

  • Education and Training

    The SJCCC is committed to efforts to develop a well-trained, diverse biomedical workforce and foster the next generation of pediatric cancer researchers

  • Community Outreach and Engagement

    St. Jude COE works with communities to increase access to cancer care, support survivors, and promote child health, ultimately improving the lives of children.

Leadership

Senior Leadership

Research Program Leaders

Cancer Biology

Cancer Control and Survivorship

Developmental Biology and Solid Tumor

Hematological Malignancies

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    Charles G. Mullighan, MBBS (Hons), MSc, MD

    Member, St. Jude Faculty

    Senior Deputy Director of Strategic Initiatives, Comprehensive Cancer Center

    Co-Leader, Hematological Malignancies Program

    Medical Director, St. Jude Biorepository

    William E. Evans Endowed Chair

    Charles G. Mullighan, MBBS (Hons), MSc, MD

    Member, St. Jude Faculty

    Senior Deputy Director of Strategic Initiatives, Comprehensive Cancer Center

    Co-Leader, Hematological Malignancies Program

    Medical Director, St. Jude Biorepository

    William E. Evans Endowed Chair

    View Full Profile Explore Charles Mullighan's research

    Affiliations

    Department of Pathology

    Center of Excellence for Leukemia Studies (CELS)

    Hematological Malignancies Program

    St. Jude Graduate School of Biomedical Sciences

    Research Interests

    • The use of integrated genomic and epigenomic approaches to understand the pathogenesis and evolution of acute lymphoblastic leukemia (ALL) and related disorders
    • Defining the interaction of inherited and somatic genetic alterations in leukemogenesis
    • The use of in vitro and in vivo experimental approaches to model genomic abnormalities in leukemogenesis
    • Preclinical therapeutic testing to translate genomic discoveries to new treatment approaches in ALL

    Contact Information

    Charles G. Mullighan, MBBS (Hons), MSc, MD

    Pathology

    MS 342, Room D4047D

    St. Jude Children's Research Hospital

    262 Danny Thomas Place

    Memphis, TN 38105-3678

    (901) 595-3387 (phone)

    (901) 595-5947 (fax)

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    Sarah Elitzur, MD

    Member, St. Jude Faculty

    Director, Leukemia/Lymphoma Division

    Co-Leader, Hematological Malignancies Program

    Sarah Elitzur, MD

    Member, St. Jude Faculty

    Director, Leukemia/Lymphoma Division

    Co-Leader, Hematological Malignancies Program

    View Full Profile

    Affiliations

    Department of Oncology

    Leukemia/Lymphoma Division

    Comprehensive Cancer Center

    Hematological Malignancies Program

    Research Interests

    • New therapeutic approaches to childhood acute leukemias
    • High-risk subgroups of childhood ALL
    • Tailored treatment strategies for hematological malignancies in patients with genetic predisposition disorders
    • Histiocytic disorders

    Contact Information

    Sarah Elitzur, MD

    Oncology

    MS 260, Room C6072

    St. Jude Children's Research Hospital

    262 Danny Thomas Place

    Memphis, TN 38105-3678

    (901) 595-2388 (phone)

Neurobiology and Brain Tumor

An NCI-Designated Cancer Center

NCI logo

NCI-designation as a comprehensive cancer center is a prestigious recognition awarded by the National Cancer Institute to institutions that demonstrate excellence in cancer research, treatment, prevention, and education. These centers are at the forefront of scientific discovery, translating cutting-edge research into advanced clinical care. They offer patients access to the latest therapies and clinical trials not widely available elsewhere. NCI-designated centers also play a crucial role in training the next generation of cancer researchers and clinicians, ensuring a continued commitment to reducing the burden of cancer through innovation and comprehensive care.

Join us

St. Jude investigators have the freedom to focus on making big discoveries, backed by extraordinary resources and support teams. We are always looking for highly motivated scientists and engineers with passion and talent to join us!

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