Psychology and Biobehavioral Medicine Clinical Trials

Diseases Treated:

Non-therapeutic

Eligibility:

This is a non-therapeutic research study open only to St. Jude patients and their caregivers.

• 15 to 22 years old 
• Primary oncology diagnosis 
• Read and speak English 

Diseases Treated:

Non-therapeutic

Eligibility:

This clinical trial is open only to patients at the St. Jude Children’s Research Hospital Hematology Clinic.

• Diagnosis of sickle cell disease (SCD)
• At least 12 years old and younger than 18 years old
• On a stable hydroxyurea dose in pill formation for 6 months or longer
• Lives with legal guardian
• Able to return to clinic at 4-week intervals

Diseases Treated:

Non-therapeutic

Eligibility:

This is a non-therapeutic research study open only to St. Jude patients and their caregivers.

• 5 to 17 years old 
• Diagnosed with malignancy or CNS neoplasm
• Identified by the St. Jude Transition Oncology Program as a patient transitioning off active cancer therapy

Diseases Treated:

Hemophilia

Eligibility:

• St. Jude hemophilia patients
• 6–18 years old
• Speak English 

Diseases Treated:

Sickle Cell Disease

Eligibility:

This is a non-therapeutic study for patients at St. Jude Children’s Research Hospital and Methodist Adult Comprehensive Sickle Cell Center.

• Diagnosis of sickle cell disease (SCD)
• 16 to 20 years old
• English is primary language

Diseases Treated:

Brain Tumors

Eligibility:

• Between 6 and 21 years old
• Diagnosis of localized low-grade glioma, craniopharyngioma, ependymoma, meningioma or germ cell tumor 
• Initiating focal cranial radiation therapy (photon or proton)
• Able to swallow pills
• Participant and parent/legal guardian speak, read and understand English
• Normal ECG and laboratory tests
• Adequate vision and hearing

Diseases Treated:

Craniopharyngioma

Eligibility:

• 21 years old or younger
• Diagnosis of craniopharyngioma

Diseases Treated:

Non-therapeutic

Eligibility:

This is a non-therapeutic clinical trial that is only open to St. Jude patients.

St. Jude Patients

• 8 to 17 years old 
• Sickle cell anemia 
• Enrolled on the Sickle Cell Clinical Research Intervention Program (SCCRIP) clinical trial 
• Completed Sickle Cell Assessment of Neuropsychology Skills (SCANS) assessment 
• Being treated with hydroxyurea (maximum tolerated dose) 
• Read and speak English

Siblings

• Siblings of St. Jude patients with sickle cell disease 
• Do not have sickle cell disease 
• 8 to 17 years old 

Diseases Treated:

Sickle Cell Disease

Eligibility:

• 25 years old or younger
• Diagnosed with severe sickle cell disease
• Has a suitable HLA-matched sibling donor or single haplotype matched (half matched) family member donor (parents or siblings)

Diseases Treated:

Non-therapeutic

Eligibility:

This is a non-therapeutic research study open only to St. Jude patients, their parents and patients' teachers.

• Patient between 4 and 6 years old
• Primary diagnosis of brain tumor or non-CNS solid tumor
• 6 to 12 months since therapy was completed (+/- 1 month) OR more than 18 months since therapy completion
• Chemotherapy was part of tumor treatment
• Able to speak and read English

Diseases Treated:

Medulloblastoma (includes all variants of medulloblastoma and posterior fossa PNET)

Eligibility:

• Diagnosis of newly medulloblastoma
• At least 3 years old and younger than 22 years old (Strata W, S or N) OR
• At least 22 years old and younger than 40 years old AND has SHH medulloblastoma (Stratum S)
• Has not received previous treatment with radiation therapy or chemotherapy
• Must start treatment within 36 days of surgery to remove the tumor

Diseases Treated:

Brain tumor

Eligibility:

This study is open only to patients at St. Jude Children’s Research Hospital.

• Diagnosis of medulloblastoma or other brain tumor
• Between 8 and 12 years old
• At least 2 years after completion of therapy
• Full-time student
• Speaks English