The Psychology Department conducts supportive care clinical trials for patients with cancer and blood disorders. These studies investigate long term effects of therapy, quality of life, and ways to improve health behaviors and psychological functioning.
St. Jude Clinical Trials
CONNECT: Social Experiences of Adolescents and Young Adults with Cancer
Diseases Treated:
Non-therapeutic
Eligibility:
This is a non-therapeutic research study open only to St. Jude patients and their caregivers.
- 15 to 22 years old
- Primary oncology diagnosis
- Read and speak English
ExAMS: Medication Adherence in Children with Sickle Cell Disease
Diseases Treated:
Non-therapeutic
Eligibility:
This clinical trial is open only to patients at the St. Jude Children’s Research Hospital Hematology Clinic.
- Diagnosis of sickle cell disease (SCD)
- At least 12 years old and younger than 18 years old
- On a stable hydroxyurea dose in pill formation for 6 months or longer
- Lives with legal guardian
- Able to return to clinic at 4-week intervals
HBTOP: Healthy Lifestyle Behaviors of Childhood Cancer Survivors
Diseases Treated:
Non-therapeutic
Eligibility:
This is a non-therapeutic research study open only to St. Jude patients and their caregivers.
- 5 to 17 years old
- Diagnosed with malignancy or CNS neoplasm
- Identified by the St. Jude Transition Oncology Program as a patient transitioning off active cancer therapy
HEMOCOG: Neurocognitive Functions, Health Literacy, and Transition Readiness in Pediatric Hemophiliacs
View TrialLEAPS: Understanding Sickle Cell Disease Transition to Adult Care
Diseases Treated:
Eligibility:
This is a non-therapeutic study for patients at St. Jude Children’s Research Hospital and Methodist Adult Comprehensive Sickle Cell Center.
- Diagnosis of sickle cell disease (SCD)
- 16 to 20 years old
- English is primary language
MEMCRT: Memantine to Prevent Thinking Problems in Children Receiving Radiation for Certain Brain Tumors
Diseases Treated:
Eligibility:
- Between 6 and 21 years old
- Diagnosis of localized low-grade glioma, craniopharyngioma, ependymoma, meningioma or germ cell tumor
- Initiating focal cranial radiation therapy (photon or proton)
- Able to swallow pills
- Participant and parent/legal guardian speak, read and understand English
- Normal ECG and laboratory tests
- Adequate vision and hearing
RT3CR: Proton Therapy for Pediatric Craniopharyngioma
Diseases Treated:
Eligibility:
- 21 years old or younger
- Diagnosis of craniopharyngioma
SCDCogO2: Analyzing Oxygen Saturation and Neurocognitive Functioning in Patients with Sickle Cell Disease
Diseases Treated:
Non-therapeutic
Eligibility:
This is a non-therapeutic clinical trial that is only open to St. Jude patients.
St. Jude Patients
- 8 to 17 years old
- Sickle cell anemia
- Enrolled on the Sickle Cell Clinical Research Intervention Program (SCCRIP) clinical trial
- Completed Sickle Cell Assessment of Neuropsychology Skills (SCANS) assessment
- Being treated with hydroxyurea (maximum tolerated dose)
- Read and speak English
Siblings
- Siblings of St. Jude patients with sickle cell disease
- Do not have sickle cell disease
- 8 to 17 years old
SCDHCT: Reduced Intensity Related Donor HCT for Patients with Severe Sickle Cell Disease
Diseases Treated:
Eligibility:
- 25 years old or younger
- Diagnosed with severe sickle cell disease
- Has a suitable HLA-matched sibling donor or single haplotype matched (half matched) family member donor (parents or siblings)
SEDYC: Social and Emotional Development in Children with Cancer
Diseases Treated:
Non-therapeutic
Eligibility:
This is a non-therapeutic research study open only to St. Jude patients, their parents and patients' teachers.
- Patient between 4 and 6 years old
- Primary diagnosis of brain tumor or non-CNS solid tumor
- 6 to 12 months since therapy was completed (+/- 1 month) OR more than 18 months since therapy completion
- Chemotherapy was part of tumor treatment
- Able to speak and read English
SJMB12: A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma/PNET
Diseases Treated:
Medulloblastoma (includes all variants of medulloblastoma and posterior fossa PNET)
Eligibility:
- Diagnosis of newly medulloblastoma
- At least 3 years old and younger than 22 years old (Strata W, S or N) OR
- At least 22 years old and younger than 40 years old AND has SHH medulloblastoma (Stratum S)
- Has not received previous treatment with radiation therapy or chemotherapy
- Must start treatment within 36 days of surgery to remove the tumor
SOCFUN: Social Functioning in Survivors of Pediatric Brain Tumors
Diseases Treated:
Brain tumor
Eligibility:
This study is open only to patients at St. Jude Children’s Research Hospital.
- Diagnosis of medulloblastoma or other brain tumor
- Between 8 and 12 years old
- At least 2 years after completion of therapy
- Full-time student
- Speaks English